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Effect of disturbance of the gastrointestinal microflora on the faecal excretion of Fusobacterium necrophorum biovar A

Published online by Cambridge University Press:  19 October 2009

G. R. Smith  and
E. A. Thornton
G. R. Smith
Affiliation:
Institute of Zoology, The Zoological Society of London, Regent's Park. London NW1 4RY
E. A. Thornton
Affiliation:
Institute of Zoology, The Zoological Society of London, Regent's Park. London NW1 4RY
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Oral pretreatment of mice with either a mixture of kanamycin and erythromycin or metronidazole to modify the gut microflora greatly enhanced the faecal excretion of Fusobacterium necrophorum biovar A given by mouth. This lends support to the suggestion that disturbance of the gastrointestinal microflora in animals such as cattle, which often carry the organism in the rumen, may lead to intestinal multiplication and faecal excretion, thereby providing a source of infection that may lead to necrobacillosis of the body surface.

Information

Type
Research Article
Information
Epidemiology & Infection , Volume 110 , Issue 2 , April 1993 , pp. 333 - 337
Copyright
Copyright © Cambridge University Press 1993

References

REFERENCES

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