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A comparative study of two live measles vaccines in Iran

Published online by Cambridge University Press:  15 May 2009

H. Mirchamsy ,
A. Shafyi ,
Y. Bassali ,
S. Bahrami  and
F. Nazari
H. Mirchamsy
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
A. Shafyi
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
Y. Bassali
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
S. Bahrami
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
F. Nazari
Affiliation:
Razi Serum Institute, P.O. Box 656, Tehran, Iran
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Summary

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The results of immunization of 523 children from 9 months to over 5 years of age with two attenuated measles vaccines, ‘Denken’ and ‘Biken’, are described. The clinical reactions following vaccination with both vaccines were mild, but Denken vaccine produced more rashes than the Biken vaccine. The serological conversion was satisfactory for both vaccines but a higher titre of neutralizing and haemagglutination-inhibiting antibodies was found in children immunized with Denken vaccine. The incidence of severe reactions or complications was negligible in this trial. The immunity to diphtheria or tetanus was not altered by vaccination with live measles vaccine.

Information

Type
Research Article
Information
Journal of Hygiene , Volume 68 , Issue 1 , March 1970 , pp. 101 - 110
Copyright
Copyright © Cambridge University Press 1970

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