Hostname: page-component-7dd5485656-7jgsp Total loading time: 0 Render date: 2025-10-31T03:31:51.048Z Has data issue: false hasContentIssue false
  • English
  • Français

Hepatoblastoma diagnosed in infancy occurring in single-ventricle patients: a case series

Published online by Cambridge University Press:  30 September 2020

McAllister O. Windom Open the ORCID record for McAllister O. Windom [Opens in a new window]  and
M. Jay Campbell
McAllister O. Windom
Affiliation:
Department of Pediatric Cardiology, Duke University Medical Center, Durham, NC 27710, USA
M. Jay Campbell
Affiliation:
Department of Pediatric Cardiology, Duke University Medical Center, Durham, NC 27710, USA
Get access Rights & Permissions [Opens in a new window]

Abstract

Hepatoblastoma is the most common primary liver tumour in children; however, there are no reported incidences in the single-ventricle congenital heart disease population. We present three cases in patients with single-ventricle heart disease with a mean age at diagnosis of 19.7 (±4) months. The diagnosis was made prior to Fontan completion in all three cases. These represent the only documented hepatoblastoma cases in single-ventricle patients.

Keywords

Single ventriclehepatoblastomacongenital heart disease

Information

Type
Brief Report
Information
Cardiology in the Young , Volume 30 , Issue 12 , December 2020 , pp. 1967 - 1969
Check for updates
Copyright
© The Author(s), 2020. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Hiyama, E. Pediatric hepatoblastoma: diagnosis and treatment. Transl Pediatrics 2014; 3: 293–299.Google ScholarPubMed
Sharma, D, Subbarao, G, Saxena, R. Hepatoblastoma. Semin Diagn Pathol 2017; 34: 192–200.CrossRefGoogle ScholarPubMed
Howlader, N, Noone, AM, Krapcho, M, et al. SEER Cancer Statistics Review, 1975–2008. National Cancer Institute, Bethesda, MD, 2011.Google Scholar
Linabery, AM, Ross, JA. Trends in childhood cancer incidence in the U.S. (1992–2004). Cancer 2008; 112: 416–432.CrossRefGoogle Scholar
Maruyama, K, Ikeda, H, Koizumi, T, et al. Case-control study of perinatal factors and hepatoblastoma in children with an extremely low birthweight. Pediatr Int 2000; 42: 492–498. CrossRefGoogle ScholarPubMed
Feusner, J, Plaschkes, J. Hepatoblastoma and low birth weight: a trend or chance observation? Med Pediatr Oncol 2002; 39: 508–509.CrossRefGoogle ScholarPubMed
Ansell, P, Mitchell, CD, Roman, E, Simpson, J, Birch, JM, Eden, TO. Relationships between perinatal and maternal characteristics and hepatoblastoma: a report from the UKCCS. Eur J Cancer 2005; 41: 741–748.CrossRefGoogle ScholarPubMed
Egbe, AC, Poterucha, JT, Warnes, CA, et al. Hepatocellular carcinoma after Fontan operation. Circulation 2018; 138: 746–748.CrossRefGoogle ScholarPubMed
Tan, ZH, Lai, A, Chen, CK, et al. Association of trisomy 18 with hepatoblastoma and its implications. Eur J Pediatr 2014; 173: 1595–1598.CrossRefGoogle ScholarPubMed
Khairy, P, Poirier, NC, Mercier, LA. Univentricular heart. Circulation 2007; 115: 800–812.CrossRefGoogle ScholarPubMed
Asrani, SK, Asrani, NS, Freese, DK, et al. Congenital heart disease and the liver. Hepatology 2012; 56: 1160–1169.CrossRefGoogle ScholarPubMed