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Herpes Zoster Ophthalmicus with Delayed Cerebral Infarction and Meningoencephalitis

Published online by Cambridge University Press:  18 September 2015

Mark S. Freedman  and
Ronald D. Macdonald
Mark S. Freedman
Affiliation:
Department of Neurology, The Wellesley Hospital and University of Toronto
Ronald D. Macdonald*
Affiliation:
Department of Neurology, The Wellesley Hospital and University of Toronto
*
The Wellesley Hospital, 160 Wellesley St. East, Toronto, Ontario M4Y 1J3 Canada
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Abstract:

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Herpes zoster ophthalmicus can be complicated by a delayed ipsilateral cerebral angiitis which may cause infarction and a smoldering meningoencephalitis. We describe such a case treated successfully with steroids and acyclovir. It is important to consider the diagnosis of this disorder early since therapeutic intervention may prevent an otherwise high morbidity and mortality. Steroids may have to be continued for some time after clinical resolution, using the ESR as a guideline for decreasing dosages.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 14 , Issue 3 , August 1987 , pp. 312 - 314
Copyright
Copyright © Canadian Neurological Sciences Federation 1987

References

REFERENCES

1.Womack, LW, Liesegang, TJ. Complications of herpes zoster ophthalmicus. Arch Ophthalmol 1983; 101: 42–45.CrossRefGoogle ScholarPubMed
2.Anastasopoulos, G, Routsonis, K, Ierodiakonow, CS. Ophthalmic herpes zoster with contralateral hemiplegia. J Neurol Neurosurg Psychiatry 1958; 21: 210–212.CrossRefGoogle ScholarPubMed
3.Acers, TE. Herpes zoster ophthalmicus with contralateral hemiplegia. Arch Ophthalmol 1964; 71: 371–376.CrossRefGoogle ScholarPubMed
4.Hilt, DC, Buchholz, D, Krumholz, A, Weiss, H, Worinsky, JS. Herpes zoster ophthalmicus and delayed contralateral hemiparesis caused by cerebral angiitis: diagnosis and management approaches. Ann Neurol 1983; 14: 543–553.CrossRefGoogle ScholarPubMed
5.Kuroiwa, Y, Furukowa, T. Hemispheric infarction after herpes zoster ophthalmicus: computed tomography and angiography. Neurology 1981; 31: 1030–1032.CrossRefGoogle ScholarPubMed
6.Menkes, DB, Bishara, SN, Corbett, AJ. Hemispheric infarction after herpes zoster ophthalmicus. J Neurol Neurosurg Psychiatry 1983; 46: 786–788.CrossRefGoogle ScholarPubMed
7.Bourdette, DN, Rosenberg, NL, Yatsu, FM. Herpes zoster ophthalmicus and delayed ipsilateral cerebral infarction. Neurology 1983; 33: 1428–1432.CrossRefGoogle ScholarPubMed
8.Reshef, E, Greenberg, SB, Jankovic, J. Herpes zoster ophthalmicus followed by contralateral hemiparesis: report of two cases and review of literature. J Neurol Neurosurg Psychiatry 1985; 48: 1221–127.CrossRefGoogle ScholarPubMed
9.Gasperetti, C, Song, SK. Contralateral hemiparesis following herpes zoster ophthalmicus. J Neurol Neurosurg Psychiatry 1985; 48: 338–341.CrossRefGoogle ScholarPubMed
10.Ehrensaft, DV, Safeni, MM. Acyclovir and disseminated varicella zoster and encephalitis. Ann Int Med 1985; 102: 421.CrossRefGoogle ScholarPubMed
11.Steele, RW, Keeney, RE, Bradsher, RW, Moses, EB, Soloff, BL. Treatment of varicella-zoster meningoencephalitis with acyclovir — demonstration of virus in cerebrospinal fluid by electron microscopy. Am J Clin Pathol 1983; 80: 57–60.CrossRefGoogle ScholarPubMed
12.Weller, TH. Varicella and herpes zoster. N Engl J Med 1983; 309: 1434–40.CrossRefGoogle ScholarPubMed
13.Balfour, HH Jr, Bean, B, Laskin, OL, et al. Burrows Wellcome collaborative acyclovir study group: acyclovir halts progression of herpes zoster in immunocompromised patients. N EngJ Med 1983; 308: 1448–53.CrossRefGoogle Scholar
14.Tabbaa, M, Selhorst, JB. Angiography in herpes zoster ophthalmicus and delayed contralateral hemiparesis. (Letter). Neurology 1985; 35: 442.CrossRefGoogle ScholarPubMed
15.Bourdette, DN, Yatsu, FM, Rosenberg, NL. Angiography in Herpes Zoster Ophthalmicus and delayed contralateral hemiparesis. (Reply to Letter). Neurology 1985; 35: 443.CrossRefGoogle Scholar
16.Vecht, CJ, Sande, JJ. Hemispheric infarction after herpes zoster ophthalmicus. Neurology 1982; 32: 914.CrossRefGoogle Scholar
17.Doyle, PW, Gibson, G, Dolman, CL. Herpes zoster ophthalmicus with contralateral hemiplegia: identification of cause. Ann Neurol 1983; 14: 84–85.CrossRefGoogle ScholarPubMed
18.Linnemann, CC Jr., Alvira, MM. Pathogenesis of varicella-zoster angiitis in theCNS. Arch Neurol 1980; 37: 239–240.CrossRefGoogle Scholar
19.Eidelberg, D, Sotrel, A, Horovpian, DS, et al. Thrombotic Cerebral Vasculopathy associated with Herpes Zoster.Ann Neurol 1986; 19: 7–14.CrossRefGoogle ScholarPubMed
20.McKenzie, RA, Forbes, GS, Karnes, WE. Angiographic findings in herpes zoster arteritis. Ann Neurol 1981; 10: 458–464.CrossRefGoogle Scholar
21.Moskowitz, MA, Henrikson, BM. Trigeminovascular neurons and the arteritis complicating herpes zoster ophthalmicus. (Letter). Neurology 1985; 35: 444.CrossRefGoogle ScholarPubMed
22.Filloux, F, Townsend, J. Herpes Zoster Ophthalmicus with ipsilateral cerebellar infarction. (Letter). Neurology 1985; 35: 1531.CrossRefGoogle ScholarPubMed
23.Moskowitz, MA, Henrikson, BM. Herpes Zoster Ophthalmicus with ipsilateral cerebellar infarction. (Reply to Letter). Neurology 1985; 35: 1531.CrossRefGoogle Scholar