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Amiodarone Producing Insidious Optic Neuropathy

Published online by Cambridge University Press:  04 January 2024

Ryan H. Mason ,
Armin Handzic Open the ORCID record for Armin Handzic [Opens in a new window] ,
Prem A. H. Nichani  and
Edward A. Margolin Open the ORCID record for Edward A. Margolin [Opens in a new window]
Ryan H. Mason
Affiliation:
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
Armin Handzic
Affiliation:
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
Prem A. H. Nichani
Affiliation:
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada
Edward A. Margolin*
Affiliation:
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada Department of Medicine, Division of Neurology, University of Toronto, Toronto, ON, Canada
*
Corresponding author: E. A. Margolin; Email: edward.margolin@uhn.ca
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Abstract

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Keywords

Amiodarone-related optic neuropathytoxic optic neuropathyoptic disk swellingneuro-ophthamology
Type
Neuroimaging Highlight
Information
Canadian Journal of Neurological Sciences , Volume 51 , Issue 4 , July 2024 , pp. 564 - 565
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of Canadian Neurological Sciences Federation

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References

Raeder, EA, Podrid, PJ, Lown, B. Side effects and complications of amiodarone therapy. Am Heart J. 1985;109:97–83. DOI: 10.1016/0002-8703(85)90238-8.CrossRefGoogle ScholarPubMed
Feiner, LA, Younge, BR, Kazmier, FJ, Stricker, BH, Fraunfelder, FT. Optic neuropathy and amiodarone therapy. Mayo Clin Proc. 1987;62:702–17. DOI: 10.1016/s0025-6196(12)65224-0.CrossRefGoogle ScholarPubMed
Murphy, MA, Murphy, JF. Amiodarone and optic neuropathy: the heart of the matter. J Neuroophthalmol. 2005;25:232–6. DOI: 10.1097/01.wno.0000177290.09649.38.CrossRefGoogle ScholarPubMed
Latini, R, Tognoni, G, Kates, RE. Clinical pharmacokinetics of amiodarone. Clin Pharmacokinet. 1984;9:136–56. DOI: 10.2165/00003088-198409020-00002.CrossRefGoogle ScholarPubMed
Mansour, AM, Puklin, JE, O’Grady, R. Optic nerve ultrastructure following amiodarone therapy. J Clin Neuroophthalmol. 1988;8:231–7.Google ScholarPubMed
Costa-Jussa, FR, Jacobs, JM. The pathology of amiodarone neurotoxicity, I: experimental studies with reference to changes in other tissues. Brain. 1985;108:735–52. DOI: 10.1093/brain/108.3.735.Google ScholarPubMed
Passman, RS, Bennett, CL, Purpura, JM, et al. Amiodarone-associated optic neuropathy: a critical review. Am J Med. 2012;125:447–53 DOI: 10.1016/j.amjmed.2011.09.020.CrossRefGoogle ScholarPubMed