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Peroral xylitol increases the concentration levels of tissue iron in the rat

Published online by Cambridge University Press:  09 March 2007

Mauri M. Hämäläinen  and
Kauko K. Mäkinen
Mauri M. Hämäläinen
Affiliation:
Department of Biochemistry, Institute of Dentistry, University of Turku, SF-20520 Turku 52, Finland
Kauko K. Mäkinen
Affiliation:
Department of Biochemistry, Institute of Dentistry, University of Turku, SF-20520 Turku 52, Finland
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Abstract

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1. The effect of xylitol feeding on the iron content of rat tissues was studied.

2. Adult male rats were fed on the basal diet containing (g/kg) 200 glucose, or 50 or 200 xylitol, or the same diet containing no added carbohydrates for 8 weeks. Each feeding group comprised nine animals.

3. Xylitol at 200 g/kg diet retarded the growth rate of the rats, whereas 200 g glucose/kg increased the weight gains compared with animals given no added carbohydrates.

4. Xylitol at 50 g/kg did not affect the tissue Fe concentrations, but 200 g xylitol/kg increased the Fe content of the livers, duodenum wall, spleen, bone marrow and serum.

5. Cadmium and lead contents of the livers were similar in all groups.

6. Xylitol–Fe complexes are suggested to be responsible for the increased Fe absorption during xylitol feeding.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 50 , Issue 1 , July 1983 , pp. 109 - 112
Copyright
Copyright © The Nutrition Society 1983

References

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