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Early life undernutrition in rats

3. Motor performance in adulthood

Published online by Cambridge University Press:  04 June 2009

J. L. Smart  and
K. S. Bedi
J. L. Smart
Affiliation:
Department of Child Health, University of Manchester, The Medical School, Oxford Road, Manchester M13 9PT
K. S. Bedi
Affiliation:
Department of Child Health, University of Manchester, The Medical School, Oxford Road, Manchester M13 9PT
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Abstract

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1. A detailed investigation was made of the motor performance of rats which had impaired cerebellar and muscular growth resulting from early-life undernutrition.

2. Developing rats were growth-retarded by underfeeding their mothers during pregnancy and lactation. They were fed ad lib. from 25 d of age.

3. Adult male previously-undernourished (PU) and well-fed control rats were given tests of motor behaviour commencing at 5 months of age. They were required to run backwards to maintain their position on a revolving drum. Aspects of the test situation were varied systematically: visual environment, interval between trials, test duration and drum speed.

4. PU rats had a 29% body-weight deficit compared with controls at 5 months.

5. There was no evidence of impaired motor performance by the PU rats under any of the test conditions.

Information

Type
Papers of direct reference to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 47 , Issue 3 , May 1982 , pp. 439 - 444
Copyright
Copyright © The Nutrition Society 1982

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