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Self-harm before and during imprisonment: cohort study of males in prison linking population-based routinely collected data in Wales

Published online by Cambridge University Press:  12 December 2025

Marcos DelPozo-Banos
Affiliation:
Swansea University Medical School, Faculty of Medicine, Health & Life Science, Swansea University, Swansea, UK National Centre for Suicide Prevention and Self-Harm Research, Swansea, UK
Mark D. Atkinson
Affiliation:
Swansea University Medical School, Faculty of Medicine, Health & Life Science, Swansea University, Swansea, UK
Sze Chim Lee
Affiliation:
Swansea University Medical School, Faculty of Medicine, Health & Life Science, Swansea University, Swansea, UK
Ann John*
Affiliation:
Swansea University Medical School, Faculty of Medicine, Health & Life Science, Swansea University, Swansea, UK National Centre for Suicide Prevention and Self-Harm Research, Swansea, UK
*
Correspondence: Ann John. Email: a.john@swansea.ac.uk
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Abstract

Background

Self-harm among UK prisoners has risen over the past decade.

Aims

To explore self-harm risk factors and mental health conditions in prisoners, pre- and during imprisonment, compared with the general population.

Method

This retrospective cohort study linked electronic health records and Ministry of Justice data for Welsh male prisoners (2019), and a comparison general population cohort. We examined imprisonment likelihood based on prior self-harm and mental health conditions using logistic regression. We also studied self-harm risk up to three years during imprisonment through Generalised Estimating Equations and time-stratified Cox regression, using a pre-imprisonment comparator (3 years before).

Results

Prisoners (N = 6095) had higher rates of self-harm and mental health conditions pre-imprisonment compared with non-prisoners (e.g. self-harm odds ratio: 2.1 (1.9, 2.2)). Self-harm risk was 5.25–6.47 times higher in prisoners than non-prisoners, both pre- and during imprisonment. Risk was highest shortly after incarceration, then declined, becoming lower than pre-imprisonment after 7 months. While most conditions correlated with higher self-harm risk during imprisonment (e.g. drug use, hazard ratios: 1.5–3.0), some (e.g. depression and alcohol use) showed weaker links in prisoners than non-prisoners, particularly from 7 months after imprisonment. Self-harm risk was seemingly higher in prisoners on remand compared with those sentenced.

Conclusions

Pre-imprisonment, self-harm in male prisoners is already high compared with the general population, potentially driving a saturation effect, where known general population risk factors have a weaker effect in prisoners. Self-harm prevention should target people in contact with criminal justice, irrespective of imprisonment. In prisons, prevention efforts deployed at inception should target those with prior self-harm, drug use, learning difficulties, bipolar disorder and those on remand.

Information

Type
Paper
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of Royal College of Psychiatrists

Self-harm in people in prisons (for simplicity, from here on referred to as ‘prisoners’) is a major public health concern causing considerable morbidity. Reference Hawton, Linsell, Adeniji, Sariaslan and Fazel1 Historical examples suggest this has been the case for at least 400 years. Reference Wilkinson2 A range of risk factors, including past and present suicidal thoughts, previous self-harm and major depression were strongly associated with self-harm in prison. Reference Favril, Yu, Hawton and Fazel3 These are not dissimilar to risk factors in the general population, and, similarly to other mental (e.g. psychotic illness, alcohol and drug use) and physical (e.g. hepatitis C) health conditions, they are broadly more prevalent in the prison population. Reference Favril, Rich, Hard and Fazel4 However, in this population, society is more directly responsible for their safety while in prison and on discharge. Self-harm during imprisonment has been reported by 5–6% of male prisoners in the UK, Reference Hawton, Linsell, Adeniji, Sariaslan and Fazel1,Reference Favril, Rich, Hard and Fazel4 of whom almost half had a previous history of self-harm. Reference Knight, Coid and Ullrich5 Previous self-harm was associated with an increased risk of suicide in prison in a systematic review and meta-analysis across 27 countries. Reference Zhong, Senior, Yu, Perry, Hawton and Shaw6 Even after release from prison, there is a highly elevated risk of suicide among male ex-prisoners (4 times higher than in the general population) and of drug-related deaths (11 times higher). 7

Most existing literature relies on self-reported measures which may add bias. In an Australian study, only 38% of prisoners with a pre-sentence history of self-harm (established by data-linkage) disclosed it during an interview, and the metric derived from health data was suggested to be a better predictor of subsequent self-harm than the self-reported metric. Reference Borschmann, Young, Moran, Spittal, Snow and Mok8 Similar strengths of using routinely collected data over self-report were reported for anxiety, depression and drug and alcohol dependency in two prisons in the north of England. Reference Wright, Hearty and Allgar9 Thus, examining electronic health records (EHRs) can shed light on risk factors for self-harm in prisoners and, importantly, allow comparison with non-prisoners. In a data-linkage study of non-indigenous males in Western Australia, those in prison were 22 times more likely to have a mental health service contact for self-harm in the year before imprisonment, and 10 times more likely to have any mental health service contact than non-offenders. Reference Sodhi-Berry, Preen, Alan, Knuiman and Morgan10 A study based in New York City prisons linking EHRs and prison administrative data showed that serious mental illness, being under 18 and being in solitary confinement contributed significantly to self-harm in prisoners. Reference Kaba, Lewis, Glowa-Kollisch, Hadler, Lee and Alper11

In Welsh prisons, there was a 200% increase in recorded self-harm events between the periods 2010–2014 and 2015–2017. Reference Jones12 In 2017 alone, the number of recorded self-harm incidents increased by 16%, compared with a 10% rise in England. Reference Jones12 However, to the best of the authors’ knowledge, large-scale population-based/data-linkage studies on self-harm in prisons based on routinely collected data are scarce. Reference Borschmann, Young, Moran, Spittal, Snow and Mok8,Reference Kaba, Lewis, Glowa-Kollisch, Hadler, Lee and Alper11 Understanding the differences in risk factors compared with the wider population could inform comprehensive prevention approaches specifically for this group. We aimed to explore risk factors, mental health conditions and comorbidities associated with self-harm in the prison population, both before and during imprisonment, and compared with the general population. We achieved this by linking routinely collected primary care, emergency department and hospital in-patient data for the Wales population with Ministry of Justice data (MoJ) data from all Welsh prisoners in Wales in 2013–2019.

Method

This was a retrospective electronic cohort study. The SAIL (Secure Anonymised Information Linkage) Databank Information Governance Review Panel granted ethical approval (approval number 1311). SAIL’s information governance is such that additional individual participants consent is not necessary for research underpinned by routinely collected data. Members of the public are informed of data use, and they can opt-out of their data being provided to SAIL. This study is reported in accordance with the RECORD (REporting of studies Conducted using Observational Routinely-collected Data) statements Reference Benchimol, Smeeth, Guttmann, Harron, Moher and Petersen13 and checklist (Supplementary T1 available at https://doi.org/10.1192/bjo.2025.10898).

Data sources

Data from the MoJ consisting of the prison population in Wales including youth offenders, during 2019, with receptions, discharges and movements information, and the Safety in Custody database with deaths, self-harm and assault events within prisons in 2013–2019 was linked within the SAIL Databank, a national repository of health and administrative data for Wales. Reference Ford, Jones, Verplancke, Lyons, John and Brown14,Reference Lyons, Jones, John, Brooks, Verplancke and Ford15 A trusted third party (Digital Health and Care Wales) assigned each individual with an anonymised linkage field which allows individual-level linkage of data-sets without disclosing identifiable information. Wales has no female or category A (high security) prisons, and therefore our data was composed only of males in lower category prisons (See Supplementary Methods).

We used four data sources from SAIL in conjunction with the data provided by the MoJ. The Welsh Demographic Service Dataset (WDSD) contained demographic data of all those registered with a primary care practice (general practice, GP) in Wales, and was the spine of the population register within SAIL. The Wales Longitudinal GP (WLGP) database contained information about primary care contacts (symptoms, diagnoses, observations, test results, administrative procedures such as referrals and prescriptions) recorded as Read codes, Reference Chisholm16 covering around 80% of the population of Wales (periods of trustworthy WLGP data for each individual Reference Thayer, Rees, Kennedy, Collins, Harris and Halcox17 ). The Emergency Department Dataset (EDDS) had information about diagnoses, investigations and treatment. The Patient Episode Database for Wales recorded clinical data (diagnoses recorded by four-digit ICD-10 codes) and administrative variables of all hospital in-patient admissions in Wales. We used all records linked deterministically or probabilistically with a linkage score ≥0.9. Reference Lyons, Jones, John, Brooks, Verplancke and Ford15

Prisoner cohort

We included those in Welsh prisons during 2019 in the study if they were resident in Wales at the time of imprisonment and registered with a GP providing data to SAIL, at least, during the year before. We defined the imprisonment date for prisoners as the date they entered a Welsh prison, regardless of whether they were sentenced or on remand.

Non-prisoner cohort

The non-prisoner comparison group consisted of pseudo-randomly selected males born between 1930 and 2004 (exclusively matched to our prison cohort). We defined the index dates by pseudo-randomly generating dates to mirror the distributions of age at entry into the prison cohort. This two-step selection process for the non-prisoner cohort allowed us to compare cohorts with similar characteristics. We then retained those residing in Wales immediately before the index date, and with linkage to GP records and registration with a SAIL recording practice, at least, during the year before.

Measures

Self-harm (outcome), as recorded in UK clinical records, is defined as non-fatal intentional self-poisoning or self-injury, regardless of suicidal motivation or intent, therefore including a range of behaviours such as non-suicidal self-injury and suicide attempts. This reflects that suicidal intent can be complex to assess and often ambivalent. Within the SAIL Databank, we ascertained self-harm from primary care, emergency department and hospital admission data using validated lists of codes and algorithms developed with expert clinicians (full details in Supplementary T2). Reference Marchant, Turner, Balbuena, Peters, Williams and Lloyd18 The Safety in Custody database had dates and details of self-harm incidents logged by prison staff. The date of the first self-harm event following the imprisonment/index date was identified in the Safety in Custody data for prisoners, and in primary care, emergency department and hospital admission records for non-prisoners as detailed above in ‘data sources’.

We measured age (as groups <25, 25–64 and 65+ years) and deprivation level at imprisonment/index date. Deprivation level was based on the locality of residence (Lower Super Output Area (LSOA) version 2011), from the WDSD data-set. We defined five deprivation levels (from Quintile 1 – least deprived to Quintile 5 – most deprived) based on quintiles of the 2011 Welsh Index of Multiple Deprivation (WIMD) associated with LSOAs. 19 We extracted prisoner status (remand or convicted) from MoJ data.

We generated dichotomous variables representing whether each of the following 12 conditions were recorded in prisoners’ and non-prisoners’ primary care and hospital admission data prior to imprisonment: attention-deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning difficulties, conduct disorder, depression, anxiety, alcohol use, drug use, bipolar disorder, schizophrenia, other psychotic disorders and self-harm. Alcohol use, drug use and self-harm were also identified from the EDDS. Ascertainment of these events was based on validated lists of codes and algorithms developed with expert clinicians (full details in Supplementary T2). Reference Marchant, Turner, Balbuena, Peters, Williams and Lloyd18,Reference Cornish, John, Boyd, Tilling and Macleod20Reference Underwood, Kendall, Berrett, Lewis, Anney and van den Bree28 We then derived additional variables with the number of comorbidities, and the number of ‘additional comorbidities’ when considering diagnoses separately (i.e. when individual diagnoses had their own variables in the model).

Statistical analysis

Data in SAIL is stored in a Db2-11 system, interrogated through SQL. Statistical analyses were carried out with R version 4.1.3 for Windows (R Core Team, Vienna, Austria; https://cran.rstudio.com/).

Comparison between prisoners and the reference population

To establish differences between prisoners and non-prisoners before imprisonment, we compared demographics, self-harm and other characteristics (see above) of these two cohorts prior to the imprisonment/index date. We ran Pearson’s chi-squared tests with Yates’ continuity correction, and univariable and multivariable stepwise logistic regression models (prisoners versus non-prisoners as the outcome variable) adjusted for individual studied conditions and number of ‘additional comorbidities’. We repeated the same stepwise analysis without including ‘additional comorbidities’. We reported effect sizes as odds ratios with 95% confidence intervals.

Association between pre-existing conditions and the occurrence of self-harm while imprisoned

To ascertain the difference in self-harm risk between prisoners and non-prisoners both during and before imprisonment, we included a counterfactual distant index date for both cohorts 3 years before their imprisonment/index date (defined above; see Fig. 1). Only individuals with imprisonment/index dates ≥01/01/2013 were included to harmonise with the initial date of our Safety in Custody database extract. We used Generalised Estimating Equations with a log-link Poisson regression model to estimate adjusted risk ratios for the association between imprisonment and subsequent self-harm. Reference Zou29 The model included the two-way interactions of cohort (‘prisoners’, ’non-prisoners’) with time period (‘imprisonment/index date’, ‘imprisonment/index date – 3 years’) and with prior self-harm. The model was also adjusted for age groups and deprivation level. To account for the correlation among observations within individuals over time, an exchangeable working correlation structure was used, with the individual identifier as the clustering variable. The robust s.e. was estimated to account for potential misspecification of the working correlation structure. The risk ratio is >1 if subsequent self-harm risk in ‘prisoners’ is greater than in ‘non-prisoners’, =1 if equal and <1 if lower. The described interaction term between cohort and time period measures how the change in the risk ratio after the imprisonment/index date compares between prisoners and non-prisoners.

Fig. 1 Study timeline for analysing time to incident self-harm event following imprisonment using time-stratified Cox regression. Max., maximum.

To study subsequent self-harm risk looking into the time elapsed between the imprisonment/index date and self-harm events we used Kaplan–Meier analysis and Cox regression modelling with the R ‘survival’ package version 3.8 for Windows (created by Terry M Therneau, Thomas Lumley, Atkinson Elizabeth and Crowson Cynthia; see https://therneau.r-universe.dev/survival). The Cox model also accounted for age (age group), deprivation (WIMD quintile) and pre-existing mental health conditions (12 studied conditions). We included four groups in the Cox model: (a) ‘non-prisoners’, (b) ‘prisoners’ groups with their imprisonment/index date as the start date (c) ‘non-prisoners – 3 years’ and (d) ‘prisoners – 3 years’ groups with their distant index date as the start date (see Fig. 1). Right censoring was either by death, 31/12/2019 (end date of this extract) or three years from start date (to avoid overlapping periods). We calculated time from start date to the date of incident self-harm. Independent variables were measured at or before the start date (Supplementary T2), as well as age and deprivation. We used linear combinations of coefficients to see the overall effect sizes (hazard ratios, with 95% confidence intervals) of the four groups with the R ‘biostat3’ package version 0.2.0 for Windows (created by Annika Tillander, Andreas Karlsson, Johan Zetterqvist, Peter Strom, Benedicte Delcoigne and Mark Clements; see https://cran.r-project.org/src/contrib/Archive/biostat3/). As the proportional hazard assumption was violated using Schoenfeld residuals (Supplementary T3), we carried out three time-stratified (follow-up 0 to 0.6 years – period 1, 0.6 to 1.6 years – period 2 and 1.6 to 3 years – period 3) Kaplan–Meier and Cox regression analyses (see Supplementary Methods and Supplementary F1). Hazard ratio is >1 if a variable is associated with subsequent self-harm, =1 if not associated and <1 if inversely associated. We compared hazard ratios between the four described groups to assess how the association changed between prisoners and non-prisoners, before and during imprisonment.

To study the difference in self-harm risk between sentenced prisoners and those in remand, we ran an additional three-group Kaplan–Meier analysis with (a) non-prisoners, (b) sentenced prisoners and (c) prisoners on remand. Prisoners on remand were censored at the time they are sentenced, by the end of their prison record if they were acquitted or by the other factors detailed above. We compared curves between non-prisoners, sentenced prisoners and prisoners on remand. A steeper curve indicates a faster accumulation of subsequent self-harm events. A lower end-point indicates higher subsequent self-harm risk.

Results

Prisoner demographics

There were 10 220 prisoners in the MoJ data-set, of which 6095 (59.6%) had the matching quality required and 4081 (39.9%) had >1 year valid GP records before the imprisonment date (Supplementary F2). At the time of imprisonment, prisoners ages ranged from 14 to 80 years, with the age distribution peaking at 22–28 years. Level of deprivation (WIMD quintile) measured at the imprisonment/index date was highly skewed, with 6% living in the least deprived and 49% in the most deprived areas (Supplementary T4). Of prisoners, 32% were on remand. Of those convicted, the most frequent sentence lengths were less than 1 year (40.7%), followed by between 1 and 2 years (18.3%).

Pre-imprisonment self-harm and health comorbidities between prisoners and non-prisoners

History of self-harm, mental health and neurodevelopmental disorders for prisoners and non-prisoners prior to the imprisonment/index date can be seen in Table 1. All conditions were more common in prisoners than non-prisoners, with the difference always statistically significant except for ASD (Table 1 and Supplementary T4).

Table 1 Summary (odds ratios, with 95% CIs in parentheses) of univariable and multivariable logistic regression analyses of likelihood of being in prison

WIMD, Welsh Index of Multiple Deprivation; ADHD, attention-deficit hyperactivity disorder; ASD, autism spectrum disorder.

a. Self-harm included.

The dependent variable is prisoner/non-prisoner (yes/no). In column 3, the number of other comorbidities for each individual is included in each analysis.

***P-value ≤ 0.0001; **P-value ≤ 0.001; not significant (NS) P-value > 0.05. An odds ratio >1 indicates a variable is more common in prisoners than non-prisoners.

The number of mental health comorbidities prior to the imprisonment/index date varied considerably between prisoners and non-prisoners, with the former generally accumulating more comorbidities. Among prisoners, 17% had no comorbidities prior to imprisonment date, compared with 64% of non-prisoners. Similarly, 60% of prisoners and 17% of non-prisoners had between two and five comorbidities (Supplementary T4). Accounting for the number of comorbidities had a substantial impact on the above logistic regression results, with learning difficulties and bipolar disorders changing even effect directions – unadjusted odds ratio >1 and adjusted odds ratio <1 (Table 1).

Results from the nested logistic regressions for risk of imprisonment (Table 2) show decreasing odds ratios for history of self-harm in models accounting for other conditions and number of ‘additional comorbidities’, but always >1 and statistically significant. Similarly, gradients of odds ratios for deprivation (higher effect sizes in more deprived areas) attenuated but remained significant for all models. Drug use presented highest odds ratios across all models. Conditions with odds ratios <1 were ASD, learning difficulties, bipolar disorder and other psychotic disorders. Results excluding ‘additional comorbidities’ from the nested regressions (Supplementary T5) are similar to the main analysis.

Table 2 Summary (odds ratios, with 95% CIs in parentheses) of nested logistic regression analysis of health history variable ascertained before Imprisonment/index date

WIMD, Welsh Index of Multiple Deprivation; ADHD, attention-deficit hyperactivity disorder; ASD, autism spectrum disorder.

a. The number of additional comorbidities accounting for diagnoses not explicitly included in each model. In these analyses, other comorbidities are also included, accounting for the mental health diagnoses not specifically included in each model.

The dependent variable is prisoners/non-prisoners (yes/no). ***P-value ≤0.0001; **P-value ≤0.001; *P-value ≤0.01; ‡P-value ≤ 0.05; not significant (NS) P-value >0.05. An odds ratio > 1 indicates a variable is more common in prisoners than non-prisoners.

Risk of self-harm while in prison

Of the 4081 ‘prisoners’ at this stage of our analysis, 3780 (92.6%) were included in the ‘prisoners’ cohort and 3366 (82.5%) in the ‘prisoners – 3 years’ cohort (Fig. 1 and Supplementary F2). Of the 402 that self-harmed while in prison, 243 (60.4%) had previously presented to healthcare services with self-harm (Supplementary T6). The risk ratio of self-harm in prisoners while in prison compared with ‘non-prisoners’ was 5.80 (95% CI 5.25–6.41), and it was not statistically significantly different to the risk ratio taken 3 years earlier (imprisonment/index date – 3 year period; Fig. 1).

Time-stratified Kaplan–Meier curves for incident self-harm in ‘prisoners’ and ‘non-prisoners’ groups after imprisonment/index date are depicted in Fig. 2, and corresponding Cox regression analyses in Supplementary T7 and Supplementary F3. More self-harm occurred in prisoners within 1.6 years after the imprisonment date (periods 1 and 2) compared with non-prisoners. History of self-harm (period 1: hazard ratio 2.3; period 2: hazard ratio 1.7), ADHD (period 1: hazard ratio 1.7; period 2: hazard ratio 2.1), ASD (period 1: hazard ratio 2.4), learning difficulties (period 1: hazard ratio 1.9; period 2: hazard ratio 3.1) and drug use (period 1: hazard ratio 1.5; period 2: hazard ratio 3.0) were associated with significantly higher risk of future self-harm. Gradients of hazard risks for deprivation were observed but were not statistically significant. Individuals in the ‘non-prisoners’ group were more likely to self-harm if they had previous history of self-harm, alcohol use and depression. Within 1.6–3 years after the imprisonment date (period 3), risk of self-harm for prisoners remained higher than non-prisoners, and history of conduct disorder (hazard risk 2.7; 95% CI: 1.3–5.2) and drug use (hazard risk 2.2; 95% CI: 1.2–4.0) were risks factors for elevated risk of self-harm.

Fig. 2 Kaplan–Meier plots for the separate time periods: (a) 0 to 0.6 years, (b) 0.6 to 1.6 years and (c) 1.6 to 3 years, showing the fraction (and 95% CIs) of prisoners and non-prisoners without self-harm incidents after their imprisonment/index dates (‘prisoners’ and ‘non-prisoners’) and after their pre-imprisonment/counterfactual index dates (‘prisoners – 3 years’ and ‘non-prisoners – 3 years’).

Analysis for prisoners three years before imprisonment (‘prisoners – 3 years’ group, Fig. 1) reveals higher incidence of self-harm compared with the ‘non-prisoners – 3 years’ group (Fig. 2) – a higher event than those observed in prisoners from 0.6 years after the imprisonment date (periods 2 and 3). In the ‘prisoners – 3 years’ group, only previous history of self-harm was associated with higher risk of future self-harm, while in the ‘non-prisoners – 3 years’ group, depression and drug use were also associated (Supplementary T7). Among prisoners, the link of subsequent self-harm with learning difficulties was only significant while in prison (hazard risk >1), and the link with conduct disorders, when significant, had opposite directions before and during imprisonment (hazard risk <1 in the ‘prisoners – 3 years’ group and hazard risk >1 in the ‘prisoners’ group).

Kaplan–Meier analysis including prisoners on remand shows comparable risk of self-harm up to 3 years following date of remand compared with sentenced prisoners (Supplementary F4). While those on remand showed a steeper curve than sentenced prisoners (especially after 18 months), confidence intervals were much wider due to smaller numbers, fully including that of sentenced prisoners.

Discussion

Although the prison population has an elevated risk of self-harm, we show that this was mostly ‘brought in’ rather than acquired during imprisonment. The risk of self-harm in prisoners was five to six times higher than in non-prisoners both 3 years prior to and during imprisonment, with no statistically significant difference between these periods. We do not rule out previously reported effects of prison environment factors such as solitary confinement, poor social support and physical or sexual victimisation while in custody. Reference Favril, Shaw and Fazel30 However, research including mental health factors (with lower granularity than us) highlight these as the main contributory factors to self-harm in prisoners, above environmental and relationship factors. Reference Favril, Shaw and Fazel30,Reference McTernan, Griffin, Cully, Kelly, Hume and Corcoran31 All conditions and behaviours considered in this study were more likely in prisoners prior to imprisonment than in non-prisoners, even after adjusting for comorbidities – except for ASD (higher prevalence of ASD in prisoners has been reported in some forensic settings, but so has the under-diagnosis in prisons Reference Ashworth32 ), learning difficulties, bipolar disorder and other psychotic disorders. Therefore, mental health factors were already disproportionally present in prisoners pre-imprisonment, and were already associated with increased risk of self-harm.

In general, we show that prisoners were three times more likely to have a self-harm event or a mental health diagnosis than the general population, and over ten times more likely to have mental health comorbidities. Indeed, the association between mental disorders and criminal offences has been long documented and explains the over-representation of mental disorders in the prison population. Reference Armour33 This is most evident for those with a history of drug use, whose imprisonment may be related with the possession or acquisition of the drugs themselves. Such findings underscore the value of early self-harm prevention and intervention to the general population (e.g. via families and schools).

Imprisonment apparently diminished risk of self-harm in the long term. Although the risk was highest immediately after the imprisonment date, it reduced after 7 months to a level slightly higher than that of non-prisoners and lower than prisoners themselves before imprisonment. A similar observation was found in a South Carolina study, Reference Smith and Kaminski34 where the earlier period of imprisonment was the time of greatest risk for self-harm, and those imprisoned for shorter periods were more likely to self-harm than those with longer sentences. In a prospective cohort study in England, a reduction in ‘clinical symptoms of suicidality’ was observed even within the first 2 months of imprisonment. Reference Hassan, Birmingham, Harty, Jarrett, Jones and King35

Our observation of a higher risk of self-harm in prisoners on remand compared with sentenced prisoners was not statistically significant. However, a similar difference has been reported elsewhere, including a lack of the above-mentioned attenuation of risk over time. Reference McTernan, Griffin, Cully, Kelly, Hume and Corcoran31,Reference Hassan, Birmingham, Harty, Jarrett, Jones and King35 Therefore, prisoners on remand should be considered particularly at risk of self-harm and suicidal behaviour. We suggest closely monitoring on entering prison, regardless of the receiving sentence. Overall, self-harm prevention efforts in prisons should focus on new arrivals and remain especially vigilant during the first 12 months, and throughout the remand period – until further data clarify the risk dynamics in this subgroup.

We found some evidence of a complex relationship between socioeconomic deprivation, imprisonment and self-harm. The association between high deprivation and the prison population, although strong, diminished to some extent after adjusting for previous self-harm and mental health comorbidities. Increasing deprivation increases the risk of self-harm on imprisonment relative to the risk before imprisonment. This is evident shortly after the imprisonment date (0 to 7 months) but is clearer in the medium term (7 to 19 months). Our findings are consistent with a longitudinal survey from New Zealand, showing a combination of adverse factors at individual, family, peer and school level can better explain future criminal behaviours than family socioeconomic status alone. Reference Fergusson, Swain-Campbell and Horwood36 Further research examining the effect of all these factors in combination to ascertain their relative importance is warranted, particularly including impulsivity given its suggested association with delinquency, Reference White, Moffitt, Caspi, Bartusch, Needles and Stouthamer-Loeber37 self-harm in young people Reference Lockwood, Daley, Townsend and Sayal38 and suicide attempts in prisoners. Reference Favril, Shaw and Fazel30

Some well-established associations between self-harm and mental health conditions Reference Singhal, Ross, Seminog, Hawton and Goldacre39,Reference Cybulski, Ashcroft, Carr, Garg, Chew-Graham and Kapur40 were weaker in prisoners than in non-prisoners, particularly prior self-harm, depression and alcohol use in relation to self-harm 1.6–3 years after the imprisonment date. For alcohol use, this is consistent with a meta-analysis of risk factors for self-harm in prison, which found no statistically significant association between the two. Reference Favril, Yu, Hawton and Fazel3 Interestingly, the described difference between prisoner and non-prisoner populations was also present in the 3 years before imprisonment. Therefore, the strength of these associations appears to be intrinsic to prisoners’ characteristics, and not related to the experience of imprisonment itself – notwithstanding the effect of prison environmental factors. Reference Favril, Shaw and Fazel30 Our results may also reflect a saturation effect by which an already elevated risk of self-harm does not increase in the same proportion when a new mental health factor presents. This saturation effect could be driven by factors common to self-harm and criminality, such as impulsivity (as described above), as well as by protective factors such as family support via visits and prohibition of alcohol or drugs during imprisonment. In the case of prior self-harm, the difference between prisoners and non-prisoners may be driven by the frequency of self-harm, particularly as the association with subsequent events weakened over time in prisoners, and models for later follow-up periods (0.6–1.6 and 1.6–3 years after imprisonment) did not capture intervening events after the imprisonment date.

We observed that the risk of self-harm for those with learning difficulties and conduct disorder was lower in prisoners 3 years before imprisonment than when in prison. This may be related to reported coping difficulties experienced by these prisoners, leading to higher levels of stress and self-harm. Reference Talbot41 Other mental health conditions with a stronger effect while in prison compared to before, albeit not as marked (larger confidence intervals overlap), are drug use, anxiety and ADHD. The literature provides further evidence supporting part of this. For example, the association of ADHD with self-harming behaviour has been previously established, Reference Allely42 as well as a relatively high prevalence of ADHD in the prison system. Reference Young and Cocallis43 Overall, self-harm prevention interventions in prisons should target, particularly, prisoners with learning difficulties, but also those with conduct disorders, drug use, anxiety and ADHD, as these are particularly vulnerable to the prison environment.

Strengths and limitations

We have presented a novel analysis that compares not only prisoners with the general population, but also with themselves 3 years before imprisonment. This has been crucial in the interpretation of our results, especially when identifying the effects of imprisonment and the prison environment. Furthermore, we conducted such analysis using routinely collected population-based data for Wales (UK), linking six different data resources at person-level, including demographic, primary and secondary care, and Welsh MoJ data.

The use of linked, routinely collected clinical and administrative data reduces bias and allows larger cohorts to be studied compared with self-reported data. However, only individuals who present to healthcare services are detected and therefore we may underestimate the prevalence of the studied mental health conditions and behaviours. This is particularly true for self-harm, exemplified by the iceberg model. Reference Geulayov, Casey, McDonald, Foster, Pritchard and Wells44 We combined data from primary care, emergency department and secondary (in-patient) care, and used validated diagnostic code lists in a bid to minimise such bias.

We had a relatively low linkage rate in the MoJ data (59.6%). A portion of this is as a result of prisoners who were resident in England prior to imprisonment, and therefore were not present in the Welsh Demographic Service data. Another factor may be prisoners without a permanent address or not registered with a GP, again making them unavailable for data linkage. For example, vulnerable groups of individuals such as the homeless, travellers and gypsies may be disproportionally represented in prison populations and among those not available for matching. Reference Aspinall45 Further investigation is needed to increase data coverage particularly to those from marginalised or underserved groups. Because of the cross-sectional nature of the MoJ data used, our non-prisoner comparison group may include ex-prisoners prior to 2019, although this is unlikely to have had a big impact in our results due to the averaging effects of our large sample. We also have limited data to quantify differences between remand and sentenced prisoners.

Self-harm in prison, and therefore in MoJ data, is ascertained differently than in population primary and secondary healthcare data. As a result, self-harm events are potentially better recorded in prison than in the community, where it highly depends on self-presentation and where it is not always identified or recorded as intentional self-harm. Reference Geulayov, Casey, McDonald, Foster, Pritchard and Wells44 This is likely to have had an impact on our results and findings. However, the risk ratio of self-harm risk while in prison (based on both SAIL and MoJ data) was not statistically significantly different to the risk ratio 3 years before (based only on SAIL data). Thus, it is likely that the recording bias is smaller than anticipated. Alternatively, the incidence of self-harm in prisoners is lower while in prison compared with before, hence counteracting the recording bias. Unfortunately, we are unable to determine with certainty which of these two alternatives are driving our findings.

This study does not include important risk factors associated with criminality and self-harm, such as family and peer factors. Similarly, we did not consider childhood maltreatment in our analyses because this would have restricted the number of individuals to those with childhood data. Finally, we only have data for the prison population in 2019, so we do not know if any prisoners have had previous convictions or if they were also in prison in the 3 years before their sentence extending to 2019.

Implications for research, policy and practice

In light of our results, early interventions for self-harm should target individuals exhibiting an inclination to unlawful behaviours, e.g. as they come in contact with the police or the justice system, and regardless of whether they are sent to prison or not. Similarly, early interventions for these individuals and universal interventions for children (given the relatively young age of prisoners) should include efforts to reduce the likelihood of unlawful behaviour. Reference Hawkins46 Such interventions could include social and emotional learning, and other elements that have been shown to be effective in reducing problematic behaviours and risk of self-harm. Reference Taylor, Oberle, Durlak and Weissberg47

Currently, those at risk of self-harm or suicide in prisons are managed under the Assessment, Care in Custody and Teamwork (ACCT) initiative. This was piloted in 2004 and deployed across the prison estate in England and Wales during 2005 and 2007. Reference Humber, Hayes, Senior, Fahy and Shaw48 An ACCT process can be opened for a prisoner following information from many sources that the prisoner may be at risk of self-harm or suicide. A concern form is completed by any member of staff, and this is passed to the wing or unit supervisor who begins the process. There is a meeting with the prisoner and an ACCT process is opened and an assessment done within 24 h. An ACCT case coordinator is appointed. Case interviews are done at intervals determined by the circumstances and a wide range of staff and external professionals are invited to these and a care plan is agreed. 49

We recommend the evaluation of self-harm for all prisoners at inception to consider prior self-harm and mental disorders noted in clinical records or disclosed. Furthermore, prisoners with prior self-harm, substance use, learning difficulties and bipolar disorder, as well as those on remand, should be considered especially at risk of self-harm. Where an ACCT process is opened, case reviews should always be scheduled at shorter intervals during the first 12 months after entering prison, to reflect the elevated risk observed in this period.

Further research is needed on specific comorbidity clusters, and on a range of characteristics of self-harming behaviours, such as method, lethality, intent, frequency of and repeated self-harm; and factors including prisoners’ personality traits (e.g. impulsivity), burdens of mental health, socioeconomic status, family background and prison-specific factors which were beyond the scope of this study. We will be able to address these with a larger and deeper data-set, which will also allow us to address the comparison between remand and sentencing. All these matters will need to be tackled for policy and practice to be fully informed.

Supplementary material

The supplementary material is available online at https://doi.org/10.1192/bjo.2025.10898

Data availability

Data are only available by application to the SAIL Databank (https://saildatabank.com/).

Acknowledgement

We would like to acknowledge all the data providers who make anonymised data available for research.

Author contributions

A.J. conceived the study. M.D.P.-B., M.D.A. and S.C.L. designed and carried out the analysis. M.D.P.-B., M.D.A. and S.C.L. wrote the manuscript. All authors contributed to editing the manuscript.

Funding

This study has been carried out as part of the Administrative Data Research (ADR) Wales programme of work. The ADR Wales programme of work is aligned to the priority themes identified in the Welsh Government’s national strategy, Prosperity for All. ADR Wales brings together data science experts at Swansea University Medical School (Swansea, UK), staff from the Wales Institute of Social and Economic Research, Data and Methods at Cardiff University (Cardiff, UK), and specialist teams within the Welsh Government to develop new evidence that supports Prosperity for All by using the SAIL Databank at Swansea University to link and analyse anonymised data. ADR Wales is part of the Economic and Social Research Council (part of UK Research and Innovation)-funded ADR UK (grant ES/S007393/1). A.J. and M.D.P.-B. were also funded by the Medical Research Council and Health Data Research UK (Grant DATAMIND: Data Hub for Mental Health Informatics Research Development, with Ref.: MR/W014386/1) and by Health and Care Research Wales (Grant NCSSHP: National Centre for Suicide and Self-Harm Prevention). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.

Declaration of interest

None.

Relevance statement

This study provides important insights into the prevalence and risk factors of self-harm, mental and neurodevelopmental conditions within the prison population. Our findings highlight that males in prisons are more likely to self-harm than non-prisoners even before imprisonment. While self-harm risk is highest upon imprisonment, it then declines over time to a level only slightly higher than that of non-prisoners and lower than prisoners themselves before imprisonment. We show that mental and neurodevelopmental disorders are already disproportionally present in prisoners pre-imprisonment, and are already associated with increased risk of self-harm. We further demonstrate the wide range and complexity of relationships between self-harm and mental health conditions in prisoners compared with non-prisoners, with higher rates of prior self-harm, drug use, alcohol use, depression and anxiety and mental health comorbidities in prisoners. Given these findings, self-harm prevention interventions should target people in contact with police and criminal justice systems, irrespective of imprisonment. In prisons, prevention efforts deployed at inception should target those with prior self-harm, drug use, learning difficulties, bipolar disorder and those on remand. However, universal self-harm interventions in prisons are still necessary to keep this highly vulnerable population safe.

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Figure 0

Fig. 1 Study timeline for analysing time to incident self-harm event following imprisonment using time-stratified Cox regression. Max., maximum.

Figure 1

Table 1 Summary (odds ratios, with 95% CIs in parentheses) of univariable and multivariable logistic regression analyses of likelihood of being in prison

Figure 2

Table 2 Summary (odds ratios, with 95% CIs in parentheses) of nested logistic regression analysis of health history variable ascertained before Imprisonment/index date

Figure 3

Fig. 2 Kaplan–Meier plots for the separate time periods: (a) 0 to 0.6 years, (b) 0.6 to 1.6 years and (c) 1.6 to 3 years, showing the fraction (and 95% CIs) of prisoners and non-prisoners without self-harm incidents after their imprisonment/index dates (‘prisoners’ and ‘non-prisoners’) and after their pre-imprisonment/counterfactual index dates (‘prisoners – 3 years’ and ‘non-prisoners – 3 years’).

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