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Why do schizophrenic patients hallucinate?

Published online by Cambridge University Press:  03 September 2003

Pieter R. Roelfsema  and
Hans Supèr
Pieter R. Roelfsema
Affiliation:
The Netherlands Ophthalmic Research Institute, 1105 BA Amsterdam, The Netherlands p.roelfsema@ioi.knaw.nlh.super@ioi.knaw.nl
Hans Supèr
Affiliation:
The Netherlands Ophthalmic Research Institute, 1105 BA Amsterdam, The Netherlands p.roelfsema@ioi.knaw.nlh.super@ioi.knaw.nl Graduate School of Neurosciences Amsterdam, Department of Visual System Analysis, Academic Medical Center (UvA), 1100 AA Amsterdam, The Netherlands
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Abstract

Phillips & Silverstein argue that schizophrenia is a result of a deficit of the contextual coordination of neuronal responses. The authors propose that NMDA-receptors control these modulatory effects. However, hallucinations, which are among the principle symptoms of schizophrenia, imply a flaw in the interactions between neurons that is more fundamental than just a general weakness of contextual modulation.

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Article Commentary
Information
Behavioral and Brain Sciences , Volume 26 , Issue 1 , February 2003 , pp. 101 - 103
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Copyright © Cambridge University Press 2003

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