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Recoverin, a calcium-binding protein in photoreceptors

Published online by Cambridge University Press:  04 February 2010

James B. Hurley
James B. Hurley*
Affiliation:
Department of Biochemistry and Howard Hughes Medical Institute, SL-15 University of Washington, Seattle, WA 98195. jbhhh@u.washington.edu
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Abstract

Recoverin is a Ca2+-binding protein found primarily in vertebrate photoreceptors. The proposed physiological function of recoverin is based on the finding that recoverin inhibits light-stimulated phosphorylation of rhodopsin. Recoverin interacts with rod outer segment membranes in a Ca2+-dependent manner. This interaction requires N-terminal acylation of recoverin. Four types of fatty acids have been detected on the N-terminus of recoverin, but the functional significance of this heterogeneous acylation is not yet clear.

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Behavioral and Brain Sciences , Volume 18 , Special Issue 3: An International Journal of Current Research and Theory with Open Peer Commentary , September 1995 , pp. 497 - 498
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Copyright © Cambridge University Press 1995

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