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  3. Pathway Analysis and Optimization in Metabolic Engineering
  • Cited by 82
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    • Publisher:
      Cambridge University Press
      Publication date:
      July 2009
      December 2002
      ISBN:
      9780511546334
      9780521800389
      9780521177481
      DOI:
      https://doi.org/10.1017/CBO9780511546334
      Dimensions:
      (247 x 174 mm)
      Weight & Pages:
      0.78kg, 324 Pages
      Dimensions:
      (244 x 170 mm)
      Weight & Pages:
      0.52kg, 324 Pages
      • Subjects:
      Life Sciences, Bioengineering, Molecular Biology, Biochemistry, and Structural Biology
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    • Selected: Digital
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    Subjects:
    Life Sciences, Bioengineering, Molecular Biology, Biochemistry, and Structural Biology
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    Book description

    Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.

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