Patients with cancer visit the Emergency Department (ED) throughout the trajectory of their disease for symptoms that result from an initial diagnosis, side effects of treatment, clinical deterioration due to disease progression, and symptom management. Cancer patients are often sicker relative to the general ED patient population, with higher admission rates and increased risk of morbidity and mortality. Therefore, practitioners in acute care settings must have knowledge or quick access to reliable and evidence-based literature to provide thorough and compassionate care to this complex patient population. This book offers a practical, case-based breakdown of oncologic emergencies seen in acute care environments. It provides real-world examples to enhance the medical care provided to patients with cancer who present to emergency departments or outpatient clinics. It also serves as a guide to those who are educating learners through case scenarios that may be incorporated into residency didactic education.