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4.3 - Administration of Blood and Blood Products in Intensive Care

from Section 4 - Therapeutic Interventions and Organ Support

Published online by Cambridge University Press:  27 July 2023

By
Ben Clevenger
Edited by
Ned Gilbert-Kawai ,
Debashish Dutta  and
Carl Waldmann
Ned Gilbert-Kawai
Affiliation:
The Royal Liverpool Hospital
Debashish Dutta
Affiliation:
Princess Alexandra Hospital NHS Trust, Harlow
Carl Waldmann
Affiliation:
Royal Berkshire Hospital, Reading
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Summary

Key Learning Points

  1. 1. Right blood, right patient, right time and right place is the key message for safe blood administration.

  2. 2. Accidental transfusion of ABO-incompatible blood is classified as a ‘never event’.

  3. 3. Most errors could be prevented by a final bedside check when performed correctly.

  4. 4. Patient blood management has three pillars of focus to reduce unnecessary transfusions: recognition and treatment of anaemia, minimisation of bleeding and blood loss and optimisation of anaemia and transfusion thresholds.

  5. 5. Unnecessary delays in transfusion can lead to death and major morbidity.

Keywords

blood transfusiontransfusion reactionanaemiapatient blood managementhaemorrhage
Type
Chapter
Information
Intensive Care Medicine
The Essential Guide
 , pp. 467 - 472
Publisher: Cambridge University Press
Print publication year: 2021

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References

References and Further Reading

Hébert, PC, Wells, G, Blachman, MA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999;340:409–17.CrossRefGoogle ScholarPubMed
Klein, AA, Arnold, P, Bingham, RM, et al. AAGBI guidelines: the use of blood components and their alternatives. Anaesthesia 2016;71:829–42.CrossRefGoogle ScholarPubMed
National Institute for Health and Care Excellence. 2015. Blood transfusion. NICE guideline [NG24]. www.nice.org.uk/guidance/ng24Google Scholar
Norfolk, D (ed). Handbook of Transfusion Medicine, 5th edn. Norwich: The Stationery Office; 2013.Google Scholar
Serious Hazards of Transfusion (SHOT). SHOT publications – articles. www.shotuk.org/shot-publications-2/750-2/Google Scholar

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