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  3. Horizontal Gene Transfer in the Evolution of Pathogenesis
  • Cited by 2
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    • Publisher:
      Cambridge University Press
      Publication date:
      September 2009
      June 2008
      ISBN:
      9780511541520
      9780521862974
      DOI:
      https://doi.org/10.1017/CBO9780511541520
      Dimensions:
      (228 x 152 mm)
      Weight & Pages:
      0.7kg, 342 Pages
      Dimensions:
      Weight & Pages:
      • Subjects:
      Genetics, Life Sciences, Pathology and Laboratory Science, Microbiology and Immunology
      Series:
      Advances in Molecular and Cellular Microbiology (16)
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    Subjects:
    Genetics, Life Sciences, Pathology and Laboratory Science, Microbiology and Immunology
    Series:
    Advances in Molecular and Cellular Microbiology (16)
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    Book description

    Horizontal gene transfer is a major driving force in the evolution of many bacterial pathogens. The development of high-throughput sequencing tools and more sophisticated genomic and proteomic techniques in recent years has resulted in a better understanding of this phenomenon. Written by leading experts in the field, this edited volume is aimed at graduate students and researchers and provides an overview of current knowledge relating to the evolution of microbial pathogenicity. This volume provides an overview of the mechanisms and biological consequences of the genome rearrangements resulting from horizontal gene transfer, in both prokaryotes and eukaryotes, as well as overviews of the key mobile genetic elements involved. Subsequent chapters focus on paradigms for the evolution of important bacterial pathogens, including Salmonella enterica, Streptococcus pneumoniae, and Staphylococcus aureus. The influence of socioeconomic parameters in the dissemination of transferable elements, such as antibiotic resistant genes in bacteria, is also discussed.

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