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  3. A Complex Systems Approach to Epilepsy
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  • Publisher:
    Cambridge University Press
    Publication date:
    06 January 2023
    26 January 2023
    ISBN:
    9781108582285
    9781009258081
    DOI:
    https://doi.org/10.1017/9781108582285
    Dimensions:
    (254 x 178 mm)
    Weight & Pages:
    0.5kg, 200 Pages
    Dimensions:
    Weight & Pages:
    • Subjects:
    Physics and Astronomy, Neurology and Clinical Neuroscience, Medicine, Statistical Physics
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    Subjects:
    Physics and Astronomy, Neurology and Clinical Neuroscience, Medicine, Statistical Physics
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    Book description

    The epilepsies are devastating neurological disorders for which progress developing effective new therapies has slowed over recent decades, primarily due to the complexity of the brain at all scales. This reality has shifted the focus of experimental and clinical practice toward complex systems approaches to overcoming current barriers. Organized by scale from genes to whole brain, the chapters of this book survey the theoretical underpinnings and use of network and dynamical systems approaches to interpreting and modeling experimental and clinical data in epilepsy. The emphasis throughout is on the value of the non-trivial, and often counterintuitive, properties of complex systems, and how to leverage these properties to elaborate mechanisms of epilepsy and develop new therapies. In this essential book, readers will learn key concepts of complex systems theory applied across multiple scales and how each of these scales connects to epilepsy.

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