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Case 43 - Parkinsonism, Ataxia, and Cognitive Impairment after Radiation Therapy

from Part 9 - Missing Radiographic Clues

Published online by Cambridge University Press:  03 November 2020

Keith Josephs ,
Federico Rodriguez-Porcel ,
Rhonna Shatz ,
Daniel Weintraub  and
Alberto Espay
Keith Josephs
Affiliation:
Mayo Clinic Alzheimer’s Disease Research Center
Federico Rodriguez-Porcel
Affiliation:
Medical University of South Carolina
Rhonna Shatz
Affiliation:
University of Cincinnati
Daniel Weintraub
Affiliation:
University of Pennsylvania
Alberto Espay
Affiliation:
University of Cincinnati
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Summary

This 60-year-old woman presented with a 6-year history of bilateral hand tremor and progressive gait impairment. She first noticed bilateral hand tremor when holding objects, followed by balance impairment, slow walking with foot dragging, and a tendency to fall forward. Within four years, she required a wheelchair for ambulation. She endorsed initial short-term memory affecting her ability to process information, which accelerated in the last year. Two years prior to the onset of her symptoms she had received chemotherapy (carboplatin and etoposide) with prophylactic whole-brain radiation as treatment for lung cancer.

Type
Chapter
Information
Common Pitfalls in Cognitive and Behavioral Neurology
A Case-Based Approach
 , pp. 137 - 140
Publisher: Cambridge University Press
Print publication year: 2020

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