Redressing the growing economic and racial segregation in American higher education will require college and university leaders at all levels and at institutions of all types and sizes to implement multiple, intersecting interventions designed to promote student success. This chapter explores the Association of American Colleges & Universities’ Guided Pathways Project as a case study for approaches to closing persistent equity gaps through persistence among community college students. In the process, it details the critical importance of colleges serving as anchor institutions within their communities. It concludes with a series of policy recommendations intended to increase access to higher education for the most economically disadvantaged members of society.