Book contents
- Multiparameter Flow Cytometry in the Diagnosis of Haematologic Malignancies
- Multiparameter Flow Cytometry in the Diagnosis of Haematologic Malignancies
- Copyright page
- Contents
- Contributors
- Preface
- Abbreviations
- Chapter 1 Flow Cytometry in Clinical Haematopathology
- Chapter 2 Antigens
- Chapter 3 Flow Cytometry of Normal Blood, Bone Marrow and Lymphatic Tissue
- Chapter 4 Reactive Conditions and Other Diseases Where Flow Cytometric Findings May Mimic Haematological Malignancies
- Chapter 5 Examples of Immunophenotypic Features in Various Categories of Acute Leukaemia
- Chapter 6 Acute Lymphoid Leukaemia and Minimal/Measurable Residual Disease
- Chapter 7 Immunophenotyping of Mature B-Cell Lymphomas
- Chapter 8 Plasma Cell Myeloma and Related Disorders
- Chapter 9 Mature T-Cell Neoplasms and Natural Killer-Cell Malignancies
- Chapter 10 Flow Cytometric Diagnosis of Classic Hodgkin Lymphoma in Lymph Nodes
- Chapter 11 Measurable Residual Disease in Acute Myeloid Leukaemia
- Chapter 12 Ambiguous Lineage and Mixed Phenotype Acute Leukaemia
- Chapter 13 Flow Cytometry in Myelodysplastic Syndromes
- Chapter 14 Future Applications of Flow Cytometry and Related Techniques
- Index
- References
Chapter 5 - Examples of Immunophenotypic Features in Various Categories of Acute Leukaemia
Published online by Cambridge University Press: 30 January 2025
Book contents
- Multiparameter Flow Cytometry in the Diagnosis of Haematologic Malignancies
- Multiparameter Flow Cytometry in the Diagnosis of Haematologic Malignancies
- Copyright page
- Contents
- Contributors
- Preface
- Abbreviations
- Chapter 1 Flow Cytometry in Clinical Haematopathology
- Chapter 2 Antigens
- Chapter 3 Flow Cytometry of Normal Blood, Bone Marrow and Lymphatic Tissue
- Chapter 4 Reactive Conditions and Other Diseases Where Flow Cytometric Findings May Mimic Haematological Malignancies
- Chapter 5 Examples of Immunophenotypic Features in Various Categories of Acute Leukaemia
- Chapter 6 Acute Lymphoid Leukaemia and Minimal/Measurable Residual Disease
- Chapter 7 Immunophenotyping of Mature B-Cell Lymphomas
- Chapter 8 Plasma Cell Myeloma and Related Disorders
- Chapter 9 Mature T-Cell Neoplasms and Natural Killer-Cell Malignancies
- Chapter 10 Flow Cytometric Diagnosis of Classic Hodgkin Lymphoma in Lymph Nodes
- Chapter 11 Measurable Residual Disease in Acute Myeloid Leukaemia
- Chapter 12 Ambiguous Lineage and Mixed Phenotype Acute Leukaemia
- Chapter 13 Flow Cytometry in Myelodysplastic Syndromes
- Chapter 14 Future Applications of Flow Cytometry and Related Techniques
- Index
- References
Summary
The term “acute leukemia” actually covers a large number of different diseases. This is mostly related to the lineage involved, yet, even in a single lineage, differences exist according to the differentiation stage where maturation blockade occurred or to the type of chromosomal/molecular anomalies associated with the disease. This chapter provides a guide of how immunophenotypic anomalies, typically identified very early in the diagnosis process, can orient further cytogenetic or molecular investigations, allowing for a faster integrated diagnosis and better focused patient management.
Keywords
- Type
- Chapter
- Information
- Publisher: Cambridge University PressPrint publication year: 2025
References
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