This chapter considers neuroscience translations and attempts to apply our knowledge of the nervous system in practical approaches. I start by discussing the traditional areas of translation, neurology and psychiatry, and the extent to which a focus on neurobiological aspects can help in addressing these conditions. I then turn to more recent claims that neuroscience can inform educational practice, including claims of pharmacological cognitive enhancement, and neurocriminology claims that we will be able to predict and prevent criminal behaviour by identifying the neural mechanisms involved. The discussion covers brain imaging and heritability approaches that try to identify biological bases that can be targeted in translations and interventions, highlighting the caveats associated with these approaches and the claims made from them.