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Chapter 13 - Perioperative Fluid Management in Children

Published online by Cambridge University Press:  06 February 2025

James Ip
Affiliation:
Great Ormond Street Hospital for Children, London
Grant Stuart
Affiliation:
Great Ormond Street Hospital for Children, London
Isabeau Walker
Affiliation:
Great Ormond Street Hospital for Children, London
Ian James
Affiliation:
Great Ormond Street Hospital for Children, London
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Summary

Intravenous fluids are routinely given to children when the enteral route is not sufficient or it’s not an option, such as during surgery and anaesthesia. Lack of understanding of the composition of fluids and the appropriate rate to administer them has been associated with serious morbidity and mortality in children. Recent evidence has shown that giving children isotonic fluids with a sodium concentration similar to plasma decreases the risk of hyponatraemia without an increase in adverse effects. This has led to a change in guidelines, which now recommend that isotonic fluids are used in children along with regular monitoring of fluid balance and electrolytes. Current evidence supported by several anaesthesia societies across the world recommend that children are allowed and should be encouraged to drink clear fluids up to one hour before elective surgery. Evidence is starting to emerge from enhanced recovery programmes in children of improved outcomes from individualised perioperative fluid therapy and avoidance of prolonged preoperative fasting. Strategies to reduce blood transfusion in children having surgery include treatment of preoperative iron deficiency, acceptance of low transfusion thresholds, cell salvage and tranexamic acid administration.

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Publisher: Cambridge University Press
Print publication year: 2025

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References

Further Reading

Arumainathan, R, Stendall, R, Visram, A. Management of fluids in neonatal surgery. BJA Education 2018; 18(7):199203.CrossRefGoogle ScholarPubMed
Blain, S, Paterson, N. Paediatric massive transfusion. BJA Education 2016; 16 (8):269–75.CrossRefGoogle Scholar
Faraoni, D, Meier, J, New, H et al. Patient blood management for neonates and children undergoing cardiac surgery: 2019 NATA guidelines. Journal of Cardiothoracic and Vascular Anesthesia 2019; 33:3249–63.CrossRefGoogle ScholarPubMed
Feld, LG, Neuspiel, DR, Foster, BA et al. Clinical practice guideline: maintenance intravenous fluids in children. American Academy of Pediatrics. Pediatrics 2018; 142(6):e20183083.CrossRefGoogle Scholar
Lewis, SR, Pritchard, MW, Evans, DJW et al. Colloids or crystalloids for fluid resuscitation in critically ill people. Cochrane Systematic Review 2018, 3 August; 8(8):CD000567. Available at: www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000567.pub7/full. Accessed 10 March 2024.Google ScholarPubMed
McNab, S, Duke, T, South, M et al. 140 mmol/L of sodium versus 77 mmol/L of sodium in maintenance intravenous fluid therapy for children in hospital (PIMS): a randomised controlled double-blind trial. Lancet 2015; 28;385(9974):1190–7.Google Scholar
McNab, S, Ware, RS, Neville, KA et al. Isotonic versus hypotonic solutions for maintenance intravenous fluid administration in children. Cochrane Systematic Review 2014, 18 December;(12):CD009457. Available at: www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD009457.pub2/full. Accessed 10 March 2024.CrossRefGoogle Scholar
National Institute for Health and Care Excellence. Intravenous fluid therapy in children and young people in hospital. NICE Guideline 29 2015. Updated 2020. Available at: www.nice.org.uk/guidance/ng29. Accessed 10 March 2024.Google Scholar
New, HV, Berryman, J, Bolton‐Maggs, PHB et al on behalf of the British Committee for Standards in Haematology. Guidelines on transfusion for fetuses, neonates and older children. British Journal of Haematology 2016; 175:784828.CrossRefGoogle ScholarPubMed
Sümpelmann, R, Becke, K, Crean, P et al. European consensus statement for intraoperative fluid therapy in children. European Journal of Anaesthesiology 2011; 28(9):637–9.CrossRefGoogle ScholarPubMed
Thomas, M, Morrison, C, Newton, R et al. Consensus statement on clear fluids fasting for elective pediatric general anesthesia. Pediatric Anesthesia 2018; 28:411–14.CrossRefGoogle ScholarPubMed

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