If we think of ourselves as the “highest” forms of life, we often think of Bacteria as the “lowest” forms of life. We also think of Bacteria as ancient, “primitive,” and ancestral. As discussed for many other extant branches of the tree of life, these views are misleading. But these views may be especially hard to jettison when thinking of Bacteria – aren’t they more ancestral than we are? But we must always come back to this idea: Bacteria are not our ancestors – they are extant cousins. As will be detailed below, all lineages of organisms descended from the LUCA; the major lineages of life did not descend from Bacteria.

The clade Bacteria includes species that are ecologically essential (e.g., as decomposers that impact the carbon cycle) and that comprise key organisms of our microbiome (e.g., the symbiotic Bacteria normally found on our skin and in our digestive tracts). Bacteria also cause many diseases, including stomach ulcers (Helicobacter pylori), tetanus (Clostridium tetani), and acne (Cutibacterium acnes).