Published online by Cambridge University Press: 09 October 2025
Multivariable techniques produce two major kinds of information: Information about how well the model (all the independent variables together) fit the data and information about the relationship of each of the independent variables to the outcome (with adjustment for all other independent variables in the analysis). Common measures of the strength of the relationship between an independent variable and the outcome are odds ratio, relative hazard, and relative risk. Adjusting for multiple comparisons is challenging; most important, is to decide ahead of time whether there will be adjustments of multiple comparisons. A common convention is to not adjust the primary outcome, but to adjust secondary outcomes for multiple comparisons.
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