As postcolonialism turned its attention to African literature, culture, and intellectual history, a number of very productive alliances between postcolonial theory and theories of globalization, subaltern studies, decoloniality, and transnational cultural studies emerged, but the relationship to poststructuralism has always been an ambivalent one. Taking Sunday Anozie’s debt to structuralism as a point of departure, the shift from structuralist to poststructuralist readings – with specific reference to Homi Bhabha, Jacques Derrida, and Achille Mbembe – is seen as indicative of a general move from a relatively static model of analysis to a more dynamic one. Using the case studies of Sony Lab’ou Tansi and Abdelkebir Khatibi, the chapter argues that the theoretical richness and dynamism of poststructuralism, as evidenced by the proliferation of its tropes and strategic gestures, demonstrates clearly its value and potential for contemporary African contexts.