Skip to main content Accessibility help
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

1 results

  • Chapter 7 - Magnetic Resonance Imaging in Dementia

  • from Section 1 - Introductory Chapters on Dementia
  • Edited by Bruce L. Miller, University of California, San Francisco, Bradley F. Boeve, Mayo Clinic, Minnesota
  • Book:
    The Behavioral Neurology of Dementia
    Published online:
    17 November 2025
    Print publication:
    11 December 2025, pp 105-123

  • Summary

    Magnetic resonance imaging (MRI) has become essential for the study of dementia. It is a supporting tool for the diagnosis of most neurodegenerative diseases and has shed light on many important aspects of disease etiology and progression. In Alzheimer’s disease and frontotemporal lobar degeneration in particular, it has helped to describe brain networks exhibiting selective vulnerability to neurodegeneration and facilitated the characterization of heterogeneity between clinical and genetic subtypes. MRI is also important for assessing vascular pathology and prion disease. Finally, most MRI modalities capture changes occurring up to decades prior to symptom onset, enabling early disease diagnosis and even prevention. Here,the main MRI techniques used to assess gray matter atrophy, among others, are described. We review recent studies in the different neurodegenerative diseases and describe the most common methodologies used, from visual rating scales to automated morphometry algorithms. Finally, we highlight progress in the theoretical modeling of neurodegenerative diseases and discuss more applied uses of MRI.