Violent variability, such as flaring activity, of planet-hosting stars is known to strongly affect prebiotic processes on their planets; therefore, its role in such processes is being extensively studied nowadays. On the contrary, the role of regular variability, such as variability of pulsating stars, has yet been unexplored. In this article, we investigate how large-amplitude variability of pulsating stars may affect the prebiotic evolution on their planets. We show that the RR Lyr type variables are particularly relevant because their lightcurves possess amplitudes, periods, and time profiles that are potentially most suitable to drive prebiotic reactions.