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neuroléptico

European Psychiatry Spanish edition (1)

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Terapia neuroléptica a dosis bajas y efectos secundarios extrapiramidales en esquizofrenia: un análisis del tamaño del efecto
C. Barbui, B. Saraceno
Journal:

European Psychiatry (Ed.Española) / Volume 4 / Issue 5 / July 1997

Published online by Cambridge University Press:

12 May 2020, pp. 323-326

Print publication:

July 1997
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Se realizó un metaanálisis de los trabajos publicados para cuantificar la eficacia de la terapia neuroléptica a dosis bajas en la reducción de los efectos secundarios extrapiramidales en pacientes esquizofrénicos. Un régimen de dosis bajas entre 50- 100 mg de equivalentes de clorpromacina, en comparación con un régimen de dosis estándar entre 200-500 mg, redujo los efectos secundarios extrapiramidales en un 0,30 (± 0,12) de desviación típica, lo que sólo es un efecto limitado.