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Let 
$\Sigma $ be a closed surface other than the sphere, the torus, the projective plane or the Klein bottle. We construct a continuum of probability measure preserving ergodic minimal profinite actions for the fundamental group of 
$\Sigma $ that are topologically free but not essentially free, a property that we call allostery. Moreover, the invariant random subgroups we obtain are pairwise distincts.
We prove that any countable non-amenable group 
$\unicode[STIX]{x1D6E4}$ admits a free, minimal, amenable, purely infinite action on the non-compact Cantor set. This answers a question of Kellerhals, Monod and Rørdam [Non-supramenable groups acting on locally compact spaces. Doc. Math.18 (2013), 1597–1626].
