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Tuberculosis (TB) has killed more people than any other infectious disease in human history and remains the leading the cause of death from a single infectious agent globally. The deadly persistence of TB reflects decades of underinvestment in research and development and insufficient efforts by governments (i.e. duty bearers) to make the benefits of scientific progress and its applications available to all people with and at risk of TB. The prevailing orientation of biomedical innovation – defined by a maximalist approach to intellectual property protection – does not prioritize the health of poor and marginalized communities which bear the greatest burden of TB. Nor do many governments’ health laws and policies keep up with scientific progress, resulting in outdated TB programs with negative outcomes for the health and human rights of individuals with TB.
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