Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

1 results

  • 6 - Genetic influences in the development of eating disorders

  • from Part II - Scientific underpinnings
    • By Shani Leor, Schneider Children's Medical Center, Petach Tikva, Israel, Orit Krispin, Schneider Children's Medical Center, Petach Tikva, Israel, Alan Apter, Schneider Children's Medical Center, Petach Tikva, Israel
  • Edited by Tony Jaffa
  • Brett McDermott, University of Queensland
  • Book:
    Eating Disorders in Children and Adolescents
    Published online:
    02 December 2009
    Print publication:
    14 December 2006, pp 70-81

  • Summary

    This chapter focuses on the genetic factors influencing the development of eating disorders (EDs). One strategy for identifying the genetic influence on EDs has been to determine whether particular psychiatric disorders or traits are expressions of a shared genetic diathesis. Two genetic strategies have predominantly been used to identify susceptibility loci for EDs on the human genome: linkage-type analyses and association studies. Linkage studies test the hypothesis of co-segregation between a marker locus and a trait within families. Association studies test whether an allele and a phenotypic trait show correlated occurrence within a population. The available data strongly suggest that the genetic influences reside in multiple genes and reflect interaction between multiple genes and the environment. The identification and analysis of endophenotypes related to EDs can therefore be of great importance for determining the genetic mechanism underlying EDs.