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16 - Breast cancer: screening and prevention
from Part IV - Cancer prevention
- By Jo Ann Rosenfeld, East State Tennessee University
Edited by Jo Ann Rosenfeld, The Johns Hopkins University
Book:

Women's Health in Mid-Life

Published online:

21 August 2009

Print publication:

25 March 2004, pp 275-286
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Summary

Breast cancer has the highest incidence and the third highest death rate for cancer in women in the USA. There are several methods of screening-self-breast examination (SBE), clinical breast examination (CBE) and mammography. Multiple randomized controlled trials (RCTs) and case-control studies have shown a 20-30% reduction in mortality in women age 50-65. A meta-analysis of eight RCTs, all following women aged 40-49 years for more than 12 years, found an 18% reduction in mortality in screened women. In a meta-analysis of studies in which women older than age 65 were included, there was a non-significant reduction in mortality up to age 70. Ultrasonography, CT scanning, and magnetic resonance imaging (MRI) are being studied for their uses in delineating breast cancer and their efficacy in detecting early breast cancer. At the moment, there is no way to prevent breast cancer, although its prevention in high-risk women is under investigation.