This essay probes the relationship between nature and infrastructure in Moxyland (2008) and Zoo City (2010), SF novels by the South African writer Lauren Beukes. I show, in one vein, how “nature” and “infrastructure” are not at all opposed in the way that ecocriticism and urban studies often suggest; in these speculative fictions, nature and infrastructure coincide, such that “nature” becomes coextensive with everyday life in these texts. At the same time, the essay uses Moxyland and Zoo City to explore a problem I take to be fundamental to literary and environmental studies in Africa, namely the place of African texts and contexts in the rapidly growing body of work on the Anthropocene, humanity’s new geologic age. Not only do these novels suggest yoking discourse on the Anthropocene to the new materialisms of scholars such as Jane Bennett or Bruno Latour, but the manner in which they do so can help us think about how to make the concept accessible to literary form.