Philo of Alexandria (about 20 BCE–50 CE) applied the logic of Platonic daimonification to the Jewish lawgiver Moses. Philo is important for three reasons: he did theoretical work identifying angels, daimones, and pure human souls. He also discussed why an angelic soul such as the pre-incarnate Moses would arrive on earth in flesh. Finally, Philo’s depiction of Moses as a living law in complete control of his emotions reinforced the ethical emphasis of the tradition. Philo's portrayal of Moses as a king descended from heaven best resembles the thought of the Hermetic Kore Kosmou.

Origen here represents Christian notions of angelification, although brief consideration is given to antecedents, namely Clement of Alexandria and the Valentinians. Origen, like Empedocles, offered a cosmic story of fall and redemption. According to Origen, humans are “cooled” intellects whose natural state is to burn with love for God. A species upgrade is part of humanity’s evolutionary design, but it takes intense moral labor. Origen offers the most speculation on the nature of angels, the original consubstantiality of angels and souls, how angels and souls fell from divine Love, and the moral means of their return.