Inherited cardiac arrhythmias are life-threatening conditions associated with a high risk of sudden cardiac death. These diseases impose a substantial psychological burden. Parents experience heightened anxiety due to uncertainty, medical interventions, and risk of adverse events. However, limited research has examined anxiety levels in affected individuals and their families.

This study aimed to assess anxiety levels in children and adolescents diagnosed with inherited cardiac arrhythmias, specifically Long QT Syndrome and Catecholaminergic Polymorphic Ventricular Tachycardia, and to identify factors influencing anxiety in both patients and parents.

A prospective, survey-based cohort study was conducted between June 2023 and June 2024, including 53 patients (0–18 years) diagnosed with inherited arrhythmias. Anxiety was assessed using the State-Trait Anxiety Inventory. Demographic and clinical variables, including disease type, invasive procedures, family history of sudden cardiac death, and parental education, were analysed.

Mothers exhibited the highest anxiety (STAI-T: 46.6 ± 10.6) while fathers had the lowest (37.3 ± 7.0). Catecholaminergic polymorphic ventricular tachycardia patients reported significantly higher anxiety (49.2 ± 7.7) than long QT syndrome patients (38.0 ± 7.0, p < 0.01). Children undergoing invasive procedures, particularly sympathetic denervation, had elevated anxiety (45.1 ± 8.2 vs. 36.5 ± 6.4, p < 0.05). Mothers of male children and those with a family history of sudden cardiac death had significantly higher anxiety (p < 0.01).

Inherited arrhythmias significantly impact psychological well-being, with mothers experiencing the highest anxiety levels. Disease severity, invasive procedures, and family history of sudden cardiac death contribute to increased anxiety, emphasising the need for psychological support in managing these conditions.