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The presence of dispersed-phase droplets can result in a notable increase in a system's drag. However, our understanding of the mechanism underlying this phenomenon remains limited. In this study, we use three-dimensional direct numerical simulations with a modified multi-marker volume-of-fluid method to investigate liquid–liquid two-phase turbulence in a Taylor–Couette geometry. The dispersed phase has the same density and viscosity as the continuous phase. The Reynolds number $Re\equiv r_i\omega _i d/\nu$ is fixed at 5200, the volume fraction of the dispersed phase is up to $40\,\%$, and the Weber number $We\equiv \rho u^2_\tau d/\sigma$ is approximately 8. It is found that the increase in the system's drag originates from the contribution of interfacial tension. Specifically, droplets experience significant deformation and stretching in the streamwise direction due to shear near the inner cylinder. Consequently, the rear end of the droplets lags behind the fore head. This causes opposing interfacial tension effects on the fore head and rear end of the droplets. For the fore head of the droplets, the effect of interfacial tension appears to act against the flow direction. For the rear end, the effect appears to act in the flow direction. The increase in the system's drag is attributed primarily to the effect of interfacial tension on the fore head of the droplets which leads to the hindering effect of the droplets on the surrounding continuous phase. This hindering effect disrupts the formation of high-speed streaks, favouring the formation of low-speed ones, which are generally associated with higher viscous stress and drag of the system. This study provides new insights into the mechanism of drag enhancement reported in our previous experiments.
We investigate the coupling effects of the two-phase interface, viscosity ratio and density ratio of the dispersed phase to the continuous phase on the flow statistics in two-phase Taylor–Couette turbulence at a system Reynolds number of $6\times 10^3$ and a system Weber number of 10 using interface-resolved three-dimensional direct numerical simulations with the volume-of-fluid method. Our study focuses on four different scenarios: neutral droplets, low-viscosity droplets, light droplets and low-viscosity light droplets. We find that neutral droplets and low-viscosity droplets primarily contribute to drag enhancement through the two-phase interface, whereas light droplets reduce the system's drag by explicitly reducing Reynolds stress due to the density dependence of Reynolds stress. In addition, low-viscosity light droplets contribute to greater drag reduction by further reducing momentum transport near the inner cylinder and implicitly reducing Reynolds stress. While interfacial tension enhances turbulent kinetic energy (TKE) transport, drag enhancement is not strongly correlated with TKE transport for both neutral droplets and low-viscosity droplets. Light droplets primarily reduce the production term by diminishing Reynolds stress, whereas the density contrast between the phases boosts TKE transport near the inner wall. Therefore, the reduction in the dissipation rate is predominantly attributed to decreased turbulence production, causing drag reduction. For low-viscosity light droplets, the production term diminishes further, primarily due to their greater reduction in Reynolds stress, while reduced viscosity weakens the density difference's contribution to TKE transport near the inner cylinder, resulting in a more pronounced reduction in the dissipation rate and consequently stronger drag reduction. Our findings provide new insights into the physics of turbulence modulation by the dispersed phase in two-phase turbulence systems.
Sediments within accretionary complexes, preserving key information on crust growth history of Central Asian Orogenic Belt, did not get enough attention previously. Here, we conduct comprehensive geochemical study on the turbidites from the North Tianshan Accretionary Complex (NTAC) in the Chinese West Tianshan orogen, which is a good example of sediments derived from juvenile materials. The turbidites, composed of sandstone, siltstone, and argillaceous siliceous rocks, are mainly Carboniferous. All the investigated samples have relatively low Chemical Index of Alteration values (35–63) and Plagioclase Index of Alteration values (34–68), indicating relatively weak weathering before erosion and deposition. The sandstone and siltstone, and slate samples display high Index of Compositional Variability values of 0.89–1.50 and 0.89–0.93, suggesting a relatively immature source. The sandstones and siltstones were mainly derived from intermediate igneous rocks, and the slates from felsic igneous rocks, formed in oceanic/continental arc settings. The investigated samples roughly display high positive εNd(t) values (mainly at +5.5 to +7.9, except one spot at +0.8), with corresponding Nd model ages at 672 Ma–522 Ma (except one at ∼1.1 Ga). Combined with the previous studies, we suggest that the turbidites in the NTAC were mainly derived from intermediate to felsic igneous rocks with juvenile arc signature, and thus the northern Chinese West Tianshan is a typical site with significant Phanerozoic crust growth.
The assessment of seed quality and physiological potential is essential in seed production and crop breeding. In the process of rapid detection of seed viability using tetrazolium (TZ) staining, it is necessary to spend a lot of labour and material resources to explore the pretreatment and staining methods of hard and solid seeds with physical barriers. This study explores the TZ staining methods of six hard seeds (Tilia miqueliana, Tilia henryana, Sassafras tzumu, Prunus subhirtella, Prunus sibirica, and Juglans mandshurica) and summarizes the TZ staining conditions required for hard seeds by combining the difference in fat content between seeds and the kinship between species, thus providing a rapid viability test method for the protection of germplasm resources of endangered plants and the optimization of seed bank construction. The TZ staining of six species of hard seeds requires a staining temperature above 35 °C and a TZ solution concentration higher than 1%. Endospermic seeds require shorter staining times than exalbuminous seeds. The higher the fat content of the seeds, the lower the required incubation temperature and TZ concentration for staining, and the longer the staining time. And the closer the relationship between the two species, the more similar their staining conditions become. The TZ staining method of similar species can be predicted according to the genetic distance between the phylogenetic trees, and the viability of new species can be detected quickly.
In vitro rearing of honey bee larvae is ideal for bioassay studies; no honey bee stable cell lines are available. Inconsistency of internal development staging of reared larvae and a susceptibility to contamination are common problems encountered. Standardized protocols on rearing larvae in vitro to make the larvae growth and development more similar to that of natural colonies are necessary to ensure the accuracy of experimental results and promote honey bee research as a model organism. Here, we concluded that when larval fasting weight was >160 mg, the time point of gut emptying can be defined as the critical point separating the larval and prepupal stages. In this way, we can conduct precise studies on the prepupal stage, such as organ remodeling during metamorphosis. Simultaneously, we further verified that recombinant AccApidaecin in genetic engineered bacteria added to the larval diet upregulated antibacterial peptide gene expression, and did not stimulate the stress response in larvae, nor did it affect the pupation rate or eclosion rate. This demonstrated that feeding recombinant AccApidaecin can enhance the individual antibacterial ability at the molecular level.
To understand the characteristics and influencing factors related to cluster infections in Jiangsu Province, China, we investigated case reports to explore transmission dynamics and influencing factors of scales of cluster infection. The effectiveness of interventions was assessed by changes in the time-dependent reproductive number (Rt). From 25th January to 29th February, Jiangsu Province reported a total of 134 clusters involving 617 cases. Household clusters accounted for 79.85% of the total. The time interval from onset to report of index cases was 8 days, which was longer than that of secondary cases (4 days) (χ2 = 22.763, P < 0.001) and had a relationship with the number of secondary cases (the correlation coefficient (r) = 0.193, P = 0.040). The average interval from onset to report was different between family cluster cases (4 days) and community cluster cases (7 days) (χ2 = 28.072, P < 0.001). The average time interval from onset to isolation of patients with secondary infection (5 days) was longer than that of patients without secondary infection (3 days) (F = 9.761, P = 0.002). Asymptomatic patients and non-familial clusters had impacts on the size of the clusters. The average reduction in the Rt value in family clusters (26.00%, 0.26 ± 0.22) was lower than that in other clusters (37.00%, 0.37 ± 0.26) (F = 4.400, P = 0.039). Early detection of asymptomatic patients and early reports of non-family clusters can effectively weaken cluster infections.
Lead-free BaTiO3 (BT)-based multilayer ceramic capacitors (MLCCs) with the thickness of dielectric layers ~9 μm were successfully fabricated by tape-casting and screen-printing techniques. A single phase of the pseudo-cubic structure was revealed by X-ray diffraction. Backscattered images and energy-dispersive X-ray elemental mapping indicated the high quality of MLCCs without observation of interaction, wrapping, or delamination. The relaxor state was confirmed by transmission electron microscopy and temperature-dependent permittivity. Impedance spectroscopy at various temperatures revealed the electrical heterogeneous response for MLCCs with high-resistive electrical components. Improved energy storage performance was obtained by multilayering, comparing with the bulk ceramics. Enhanced recoverable energy density ~6.88 J/cm3 with high efficiency ~90% were realized under an electric field of 820 kV/cm, which is mainly attributed to the intrinsic high-resistivity and relaxor behavior. Furthermore, good temperature (20–85 °C) and frequency stabilities (0.5–50 Hz) were observed in the MLCCs, which are attractive for pulsed power applications.
The frequency division multiple access (FDMA) strategy used in GLONASS causes inter-frequency phase bias (IFPB) and inter-frequency code bias (IFCB) between receivers from different manufacturers. The existence of IFPB and IFCB significantly increases the difficulties of fixing GLONASS ambiguity and limits the accuracy and reliability of GLONASS positioning. Moreover, the initial value of IFPB and IFCB may be unavailable or unreliable with the increasing number of receivers from different manufacturers in recent years. In this study, a real-time and reliable calibration algorithm of IFPB and IFCB based on multi-GNSS assistance is proposed by providing a fixed solution. Real-time IFPB rate and IFCB can be obtained using this algorithm without the initial IFPB and IFCB. The IFPB rate for all GLONASS satellites and IFCB for each GLONASS satellite are estimated due to different characteristics of IFPB and IFCB. IFPB calibration can be divided into constant and real-time IFPB calibrations to meet the different positioning requirements. Results show that constant IFPB rate has only 2 mm difference from the mean value of real-time IFPB rate. The IFPB rate and IFCB estimated by this algorithm have excellent stability, and the change in reference satellite cannot affect the results of IFPB rate and the stability of IFCB. The centimetre-level positioning results can be obtained using two calibration methods, and the positioning results with real-time calibration method are 10%–20% better than those with the constant calibration method. Under satellite-deprived environments, the improvements of multi-GNSS positioning accuracy with constant inter-frequency bias calibration gradually increase as the satellite cut-off elevation angle increases compared with GPS/BDS, which can reach up to 0·9 cm in the vertical direction.
In this paper, instabilities in the flow over a circular cylinder of diameter $D$ with dual splitter plates attached to its rear surface are numerically investigated using the spectral element method. The key parameters are the splitter plate length $L$, the attachment angle $\unicode[STIX]{x1D6FC}$ and the Reynolds number $Re$. The presence of the plates was found to significantly modify the flow topology, leading to substantial changes in both the primary and secondary instabilities. The results showed that the three instability modes present in the bare circular cylinder wake still exist in the wake of the present configurations and that, in general, the occurrences of modes A and B are delayed, while the onset of mode QP is earlier in the presence of the splitter plates. Furthermore, two new synchronous modes, referred to as mode A$^{\prime }$ and mode B$^{\prime }$, are found to develop in the wake. Mode A$^{\prime }$ is similar to mode A but with a quite long critical wavelength. Mode B$^{\prime }$ shares the same spatio-temporal symmetries as mode B but has a distinct spatial structure. With the exception of the case of $L/D=0.25$, mode A$^{\prime }$ persists for all configurations investigated here and always precedes the transition through mode A. The onset of mode B$^{\prime }$ occurs for $\unicode[STIX]{x1D6FC}>20^{\circ }$ with $L/D=1.0$ and for $L/D>0.5$ with $\unicode[STIX]{x1D6FC}=60^{\circ }$. The characteristics of all the transition modes are analysed, and their similarities and differences are discussed in detail in comparison with the existing modes. In addition, the physical mechanism responsible for the instability mode B$^{\prime }$ is proposed. The weakly nonlinear feature of mode B$^{\prime }$, as well as that of mode A$^{\prime }$, is assessed by employing the Landau model. Finally, selected three-dimensional simulations are performed to confirm the existence of these two new modes and to investigate the nonlinear evolution of the three-dimensional modes.
Employing atomic-scale simulations, the response of a high-angle grain boundary (GB), the soft/hard GB, against external loading was systematically investigated. Under tensile loading close to the hard orientation, strain-induced dynamic recrystallization was observed to initiate through direct soft-to-hard grain reorientation, which was triggered by stress mismatch, inhibited by surface tension from the soft-hard GB, and proceeded by interface ledges. Such grain reorientation corresponds with expansion and contraction of the hard grain along and perpendicular to the loading direction, respectively, accompanied by local atomic shuffling, providing relatively large normal strain of 8.3% with activation energy of 0.04 eV per atom. Tensile strain and residual dislocations on the hard/soft GB facilitate the initiation of dynamic recrystallization by lowering the energy barrier and the critical stress for grain reorientation, respectively.
Previous studies have supported the theory that there is a positive association between ferritin and carotid atherosclerosis in Western people. Diet plays an important role in determining serum ferritin concentration. Asian dietary patterns are different from Western dietary patterns, implying that there may be a difference in the association of ferritin with carotid atherosclerosis between Asian and Western people. However, few studies focus on the association between ferritin and carotid atherosclerosis among Asians. The aim of this study was to investigate how serum ferritin levels are associated with carotid atherosclerosis in an Asian adult population. A cross-sectional assessment was performed in 8302 adults in Tianjin, China. Carotid intima-media thickness (IMT) and plaques were assessed using ultrasonography, and serum ferritin was measured using the protein chip-chemiluminescence method. Multiple logistic regression analysis was used to examine the association between quartiles of serum ferritin concentration and carotid atherosclerosis. In the present study, the overall prevalence of IMT and carotid plaques in participants is 29·2 and 22·7 %, respectively. In women, after adjustments for potentially confounding factors, the OR of IMT and carotid plaques by increasing serum ferritin quartiles were 1·00, 1·39 (95 % CI 0·98–1·99), 1·39 (95 % CI 0·99–1·97), 1·81 (95 % CI 1·30–2·55) (Pfor trend<0·001) and 1·00, 1·24 (95 % CI 0·89–1·73), 1·18 (95 % CI 0·85–1·65), 1·59 (95 % CI 1·15–2·20) (Pfor trend<0·01), respectively. However, no association was found between serum ferritin and carotid atherosclerosis in men. The study demonstrated that increased serum ferritin levels are independently associated with IMT and carotid plaques in Asian women but not in Asian men.
We apply the tools of continued fractions to tackle the Diophantine approximation, including the classic Jarník–Besicovitch theorem, localized Jarník–Besicovitch theorem and its several generalizations. As is well known, the classic Jarník–Besicovitch sets, expressed in terms of continued fractions, can be written as
where $T$ is the Gauss map and $a_{n}(x)$ is the $n$th partial quotient of $x$. In this paper, we consider the size of the generalized Jarník–Besicovitch set
We generalise the mass transference principle established by Beresnevich and Velani to limsup sets generated by rectangles. More precisely, let {xn}n⩾1 be a sequence of points in the unit cube [0, 1]d with d ⩾ 1 and {rn}n⩾1 a sequence of positive numbers tending to zero. Under the assumption of full Lebesgue measure theoretical statement of the set
where a = (a1, . . ., ad) with 1 ⩽ a1 ⩽ a2 ⩽ . . . ⩽ ad and Ba(x, r) denotes a rectangle with center x and side-length (ra1, ra2,. . .,rad). When a1 = a2 = . . . = ad, the result is included in the setting considered by Beresnevich and Velani.
Neuromyelitis optica (NMO) and multiple sclerosis (MS) are inflammatory demyelinating diseases of human central nervous system (CNS) with complex pathogenesis. IL-21/IL-21R regulates activation, proliferation and survival of both T cells and B cells, which are involved in the pathogenesis of NMO and MS. High levels of serum IL-21 were observed in NMO patients. However, concentration of cerebrospinal fluid (CSF) IL-21 in MS and NMO patients still remain unknown.
Object:
To detect the CSF concentration of IL-21 in NMO and MS patients and to evaluate its relationship with disease activity, particularly concerned about its impact on humoral immunity.
Methods:
CSF IL-21 was detected by an enzyme-linked immunosorbent assay (ELISA) in NMO patients (n=21), MS patients (n=20) and controls (n=16).
Results:
CSF concentration of the IL-21 was noticeably elevated in NMO (p=0.012) and borderline significantly increased in MS (p=0.115). In addition, this occurrence was associated with humoral immune activity as shown by a correlation between IL-21 and complement in NMO cohort (p=0.023) and high IL-21 levels in autoantibody-positive subgroup (p=0.027).
Conclusions:
The concentration of CSF IL-21 was noticeably elevated and might have a positive correlation with humoral immune activity in NMO.
Human infection with the emerging avian influenza A(H7N9) virus in China in 2013 has raised global concerns. We conducted a retrospective descriptive study of 27 confirmed human influenza A(H7N9) cases in Jiangsu Province, to elaborate poultry-related exposures and to provide a more precise estimate of the incubation periods of the illness. The median incubation period was 6 days (range 2–10 days) in cases with single known exposure and was 7·5 days (range 6·5–12·5 days) in cases with exposures on multiple days, difference between the two groups was not significant (Z = −1·895, P = 0·058). The overall median incubation period for all patients was estimated to be 7·5 days (range 2–12·5 days). Our findings further highlight the necessity for public health authorities to extend the period of medical surveillance from 7 days to 10 days.
A novel path planner is presented for the local path planning of a single robot (represented with R) in a complicated dynamic environment. Here a series of attractive points are computed based on attractive segments for guiding R to move along a shorter path. Each attractive segment is obtained by using the full environmental knowledge and will be used for several sampling times in general. A motion controller, which is designed based on artificial moments and a robot model that has a principal motion direction line(PMDline), makes R move closely to attractive points while away from obstacles. Attractive and repulsive moments are designed, which only make R's PMDline face toward attractive points and opposite to obstacles in general, as in most cases, R will move along its PMDline with its full speed. Because of the guidance of attractive points and R's full-speed motion, the global convergence is guaranteed. Simulations indicate that the proposed path planner meets the requirements of real-time property while can optimize R's traveling path.
Crystallographic and X-ray powder diffraction data were derived from a sample of (Na0.5Bi0.5)TiO3 synthesized by standard ceramic techniques. The powder data were indexed on a monoclinic cell having the space group P2 or Pm, which differed from a previously reported rhombohedral cell.
Thermochronometer data offer a powerful tool for quantifying a wide range of geologic processes, such as the deformation and erosion of mountain ranges, topographic evolution, and hydrocarbon maturation. With increasing interest to quantify a wider range of complicated geologic processes, more sophisticated techniques are needed. This paper is concerned with an inverse problem method for interpreting the thermochronometer data quantitatively. Two novel models are proposed to simulate the crustal thermal fields and paleo mountain topography as a function of tectonic and surface processes. One is a heat transport model that describes the change of temperature of rocks; while the other is surface process model which explains the change of mountain topography. New computational algorithms are presented for solving the inverse problem of the coupled system of these two models. The model successfully provides a new tool for reconstructing the kinematic and the topographic history of mountains.
A novel ZnO/TiO2 assorted photoelectrode for dye-sensitized solar cells (DSSCs) is proposed. The impacts of the ZnO/TiO2 assorted photoelectrode on the photovoltaic performance of dye-sensitized solar cells (DSSCs) were investigated. The measurements of the light transmission spectra showed the higher transmittance through ZnO/FTO than through FTO during the effective wavelength region of 536nm˜800nm for DSSCs, indicating that ZnO/TiO2 assorted photoelectrode is beneficial for the photovoltaic performance of DSSCs. The measurements on the photovoltaic characteristics of the DSSC cell indicate that the inserted ZnO layer can cause the increased open circuit voltage (Voc) more than 70 mV and fill factor (FF) but the decreased short circuit current. The enhanced Voc and FF could be attributed to the suppressed the recombination of photon-generated carriers between the ZnO/TiO2 assorted photoelectrode and electrolyte (dye) compared to TiO2 photoelectrode. However, the additional series resistance of inserted ZnO layer causes the reduced short circuit current. The optimized conversion efficiency can be achieved in the DSSC with ZnO/TiO2 assorted photoelectrode by using low series resistance of ZnO layer.
Radar, aerial netting and ground sampling were used to study the autumn migration of Nilaparvata lugens (Stål) in Jiangsu Province in east central China. Emigration of macropterous adults increased from late August until late September as the main rice crop matured and was harvested. In early and mid September, the resulting windborne migrations carried the planthoppers mainly towards the west, although the migration directions ranged (within the western sector) from south to north. By late September, however, displacements were predominantly to the south-west on the then prevailing north-east monsoon winds: migration was particularly rapid when the north-easterlies were reinforced by typhoons. Although in late September such movements to more southerly latitudes are essential for the survival of the planthoppers' progeny, we found no definite evidence for preferential emigration on winds blowing towards the south. There were, however, indications that when winds towards the north occurred, the duration of migratory flight was curtailed. Irrespective of any possible preference for migration on northerlies, a large proportion of the N. lugens population would normally be carried in an adaptive southwards direction, because the advent of the north-east monsoon occurs at a time when the number of flight-ready planthoppers approaches its peak.