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River and wetland case studies from contrasting landscape settings with differing sediment cascades and (dis)connectivity relationships in Australia and New Zealand present contrasting sediment ‘problems’. Here we use the concept of switches that regulate the operation of buffers, barriers and blankets as a basis to develop catchment-scale sediment management plans. We present plans for managing sediment (dis)connectivity for each case study. We conclude with five key factors that practitioners need to consider when embarking on managing sediment (dis)connectivity of rivers and wetlands in practice.
Scholarly literature claims that health declines in populations when optimism about investing in the future wanes. This claim leads us to describe collective optimism as a predictor of selection in utero. Based on the literature, we argue that the incidence of suicide gauges collective optimism in a population and therefore willingness to invest in the future. Using monthly data from Sweden for the years 1973–2016, we test the hypothesis that the incidence of suicide among women of child-bearing age correlates inversely with male twin births, an indicator of biological investment in high-risk gestations. We find that, as predicted by our theory, the incidence of suicide at month t varies inversely with the ratio of twin to singleton male births at month t + 3. Our results illustrate the likely sensitivity of selection in utero to change in the social environment and so the potential for viewing collective optimism as a component of public health infrastructure.
The ‘DOHaD’ literature argues that stressors encountered at age t ‘program’ individual health at age t+n, and that this programming appears strongest when t defines critical developmental periods including gestation. Accordingly, children of ill-nourished pregnant women suffer greater later life morbidity than do offspring of well-nourished mothers. The possibility that circumstances other than access to nutritious food drive both a mother’s diet and fetal development remains, however, a threat to the inference of programming in utero. Attempts to rule out this threat include tests of the hypothesis that birth cohorts in gestation during famines exhibit shorter life spans than other cohorts. The tests produce conflicting results attributed to confounding by autocorrelation, selective migration and introduction of modern medicine. We offer a test in which neither medicine nor migration nor autocorrelation could obscure the presumed effect. We apply time-series regression methods to the life span of Swedes born between 1751 and 1800 to test the hypothesis that cohorts exposed in utero to the Swedish Famine of 1773 lived shorter lives than expected from trends and other forms of autocorrelation. We use these 50 birth cohorts not only because they included those exposed to severe famine but also because they may well be the only human birth cohorts that completed life unaffected by selective migration and unaided by modern medicine and for which we know life span. We find that the cohort born in 1773 live 4.2 years longer than expected from trends over the last half of the 18th century.
Psychological interventions may be beneficial in bipolar disorder.
To evaluate the efficacy of psychological interventions for adults with bipolar disorder.
A systematic review of randomised controlled trials was conducted. Outcomes were meta-analysed using RevMan and confidence assessed using the GRADE method.
We included 55 trials with 6010 participants. Moderate-quality evidence associated individual psychological interventions with reduced relapses at post-treatment (risk ratio (RR) = 0.66, 95% CI 0.48–0.92) and follow-up (RR = 0.74, 95% CI 0.63–0.87), and collaborative care with a reduction in hospital admissions (RR =0.68, 95% CI 0.49–0.94). Low-quality evidence associated group interventions with fewer depression relapses at post-treatment and follow-up, and family psychoeducation with reduced symptoms of depression and mania.
There is evidence that psychological interventions are effective for people with bipolar disorder. Much of the evidence was of low or very low quality thereby limiting our conclusions. Further research should identify the most effective (and cost-effective) interventions for each phase of this disorder.
Admissions to hospital following parasuicide in one city over eighteen years exhibit a cyclical variation apparently synchronized with the lunar quarters. The effect would only account for approximately 0·7 out of the average of 46 parasuicides per 100000 adults per lunar cycle (95% CI 0·6–0·8), and fails to reach statistical significance.
The influence of uniform flow acceleration on the stability and the characteristics of circular-cylinder wakes over a Reynolds-number range, 20 < R < 330, was investigated. Experiments were performed to examine the temporal evolution of the wake before, during, and after the onset of the wake instability. We have demonstrated in several ways that the wake is stabilized by flow acceleration: (i) the onset of the wake instability occurs at larger Reynolds numbers than in the steady flow case, (ii) the closed wake develops to states that would be unstable in a steady flow, and (iii) once vortex shedding does occur there is a reduction in instantaneous Strouhal number. We have also examined the temporal growth rate of the wake instability and find that it is directly proportional to the applied flow acceleration. Physical mechanisms are proposed to describe the experimental observations.
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