The COVID-19 global pandemic had a profound effect on scientific practice. During this time, officials crucially relied on the work done by modelers. This raises novel questions for the philosophy of science. Here I investigate the possibility of 'natural models' in predicting the SARS-Cov-2 virus’s trajectory for epidemiological purposes. I argue that to the extent that these can be considered scientific models, they support the possibility of a continuum from scientific models to natural models differing in artifactual commitment. In making my case, I draw from work on both model organisms and natural experiments as well as recent work in epidemiology.