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Mood disorders are a leading cause of illness and disability in children and adolescents. Effective treatment is available, and early identification and intervention improves prognosis. This chapter provides a comprehensive summary of the epidemiology, aetiology and clinical features of depression and bipolar disorder in young people. We provide evidence-based recommendations for the prevention and treatment of mood disorders in children and adolescents, including psychological and pharmacological interventions, and novel and emerging treatment options. We present research on predictors of treatment outcome and prognosis of mood disorders in young people, and highlight areas for further research. This chapter will help clinicians identify and treat young people with mood disorders in a range of clinical settings.
Eating disorders and psychotic disorders represent two of the most serious psychiatric conditions. Emerging lines of evidence from genetic and epidemiological studies suggest that these disorders may commonly co-occur. This systematic review investigated the association between these disorders across community and clinical populations.
Method
A systematic review was preregistered (CRD42021231771) and conducted according to PRISMA guidelines. Web of Science, PsycINFO and Medline were searched for articles on the association and comorbidity between psychosis and eating disorders up to the 26th February 2024. A random effects meta-analysis was conducted for studies reporting comorbidity of eating disorders and psychotic disorders based on clinical diagnosis or interview measures, to estimate prevalence of the comorbidity between these disorders. A narrative synthesis was conducted for all other studies and grouped by sample (general population, eating disorders or psychotic disorders).
Results
In total 43 studies met inclusion criteria for the systematic review and 16 were included in the meta-analysis. Findings suggest substantial comorbidity between eating disorders and psychotic disorders, with a pooled comorbidity prevalence of 8% (CI: 3, 14) based on clinical diagnosis or interview measures. Studies using self-report questionnaires also highlight the association between eating disorders and psychosis across clinical and community populations.
Conclusions
Eating disorders and psychotic disorders frequently co-occur. Further research should investigate the temporal order of symptom development and consider the need for novel interventions targeted at overlapping psychotic and eating disorder symptoms and associated phenomena.
Audit and feedback is widely used to improve physician performance. Many data metrics are being provided to physicians, yet most of these are driven by the regulatory environment. We sought to conduct a needs assessment of audit and feedback metrics that were most useful to clinicians within our health care region.
Methods
We conducted a Web-based survey of five clinical practice sites in our region and asked that physicians rank 49 clinical practice metrics. In addition, we assessed their readiness for audit and feedback and their preferences for data confidentiality. We collected data on duration of training, gender, and site of practice (academic v. community) allowing for comparison between groups.
Results
A total of 104 emergency medicine physicians participated in the survey (52.3% response rate). There was a significant readiness for participation in audit and feedback activities. Top ranked metrics were emergency department return rates and colleague's assessment of collegiality and quality of care, which were common across all sites. Small yet significant differences were noted between genders and academic v. community practitioners.
Conclusion
This study represents the first regional analysis of physician preferences for audit and feedback activities and implementation. It demonstrates that physicians are interested in audit and feedback activities and provides a roadmap for the development of a regional audit and feedback structure. It will also be used as a guiding document for regional change management.
The Southern Hemisphere VLBI Experiment (SHEVE) program is aimed at producing high-resolution images of southern radio sources. The radio telescopes of the present SHEVE array are described below and some recent results presented.
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