GOCCHI – Contact Details
Country
Chile
Chairman
Dr J. Gutiérrez, GOCCHI, Chilean Cooperative Group for Oncologic Research, Eliodoro Yánez 2967, Depto. 41, Providencia, SANTIAGO, CHILE. Tel: +56 2 233 0798 Fax: +56 2 231 0983 Email: jgutierr@clinicalascondes.cl
Vice-Chairwoman
Dr L. Bronfman, Email: luciabronfman@entelchile.net
Scientific Director
Dr R. Arriagada, Email: arriagada@igr.fr
Secretary
Dr R. Schwartz, Email:rschwart@utr.net
Treasurer
Dr A. Pinto, Email: rschwart@utr.net
Directors
Dr N. Aliaga, Email: naliagam@vtr.net
Dr R. Baeza, Email: ramon.baeza@iram.cl
Dr A. Corvalán, Email: corvalan@med.puc.cl
Dr C. del Castillo, Email: darfa@vtr.net
Dr J. Madrid, Email: madrid@iram.cl
Dr A. Majlis, Email: amajlis@entelchile.net
Dr B. Müller, Email: bmuller@manquehue.net
Dr Peralta, Email: octavioperalta@entelchile.net
Dr C. Ramos, Email: christianramos@terra.cl
Data Manager
Ms M. Zúñiga, Email: maricarmen@gocchi.org
Regulatory Trials Coordinator
Mrs M.F. Chinchón, Email: datacenter@gocchi.org
CRA
Mrs. C. Mariani, Email: cmariani@gocchi.org
Accountant and Computer Programmer
Mr C. Díaz, Email: cdiaz@gocchi.org
Website
Title
Molecular marker for dissemination in breast carcinoma.
Coordinator(s)
Dr J. Gutiérrez, GOCCHI, Chilean Cooperative Group for Oncologic Research, Eliodoro Yánez 2967, Depto. 41, Providencia, SANTIAGO, CHILE. Tel: +56 2 233 0798 Fax: +56 2 231 0983 Email: jgutierr@clinicalascondes.cl
Dr A. Corvalán, Department of Pathology, Catholic University of Chile, 85 Lira St, SANTIAGO, CHILE. Email: corvalan@med.puc.cl
Summary
- To identified specific oncogenes and tumor supressor genes in 10 retrospectively collected breast carcinomas, 5 without lymph node metastases and 5 with lymph node metastases using cDNA microarray technology. The five most relevant genes will be confirmed by RealTime PCR and tumour suppressor genes with significant down regulation will be evaluated for epigenetic inactivation. If confirmed, plasma from independent group of cases will be tested for selected genes for evaluation as clinical markers for dissemination.
Scheme
None available
Update
- Started March 2005; proposed end date, December 2007.
Related Publications
Abstract presented at the Latin American Congress of Breast Cancer, November 2005, Santiago, Chile.
Topics
- Breast carcinoma
- Epigenetics
- Methylation
Keywords
Breast carcinoma, molecular markers, RealTime PCR