Hostname: page-component-745bb68f8f-cphqk Total loading time: 0 Render date: 2025-01-11T06:03:47.526Z Has data issue: false hasContentIssue false
  • English
  • Français

Encephalopathy Resembling Creutzfeldt–Jakob Disease Following Oral, Prescribed Doses of Bismuth Nitrate

Published online by Cambridge University Press:  02 January 2018

Michael J. Von Bose  and
Michael Zaudig
Michael J. Von Bose
Affiliation:
Max-Planck-Institute for Psychiatry, Kraepelinstr. 10, D-8000 München 40, Germany
Michael Zaudig*
Affiliation:
Max-Planck-Institute for Psychiatry, Kraepelinstr. 10, D-8000 München 40, Germany
*
∗Correspondence
Get access Rights & Permissions [Opens in a new window]

Abstract

A patient given bismuth nitrate in the recommended dose range over 16 months developed panic attacks and a major depressive syndrome and, after 15 months, a myoclonic encephalopathy resembling Creutzfeldt–Jakob disease. He recovered four months after bismuth had been discontinued. Bismuth preparations are becoming popular in the treatment of gastritis; close attention to neurological and psychiatric symptoms seems mandatory.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 158 , Issue 2 , February 1991 , pp. 278 - 280
Copyright
Copyright © Royal College of Psychiatrists, 1991 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Adams, R. D. & Victor, M. (eds) (1981) Tremors, myoclonus, spasm and tics. In Principles of Neurology. New York: McGraw-Hill.Google Scholar
American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM–III–R). Washington, DC: APA.Google Scholar
Baringer, J. R. et al (1968) An acute syndrome of ocular oscillations and truncal myoclonus. Brain, 91, 473.Google Scholar
Boersch, G. (1988) Campylobacter pylori und Therapie mit Wismuthsalzen. Medizinische Monatsschrift für Pharmazeuten, 9, 301–307.Google Scholar
Bouche, P. & Derouesne, C. (1977) Encephalopathy after oral ingestion of bismuth salt over a short time period (10 days). La Nouvelle Presse Médicale, 36, 3336.Google Scholar
Buge, A. Supino-Viterbo, V. Rancurel, G. et al (1981) Epileptic phenomena in bismuth toxic encephalopathy. Journal of Neurology, Neurosurgery and Psychiatry, 44, 62–67.Google Scholar
Krüger, G. (1984) Wismuth Enzephalopathie. Fortschritte der Neurologie und Psychiatrie, 52, 24–31.Google Scholar
Monstrey, J. van den Eeckhout, E. Djudzman, R. et al (1978) Bismuth encephalopathy. A clinical and anatomo-pathological report of one case. Acta Neurologica Belgica, 78, 301–309.Google Scholar
Supino-Viterbo, V. Sicard, C. Risvegliato, M. et al (1977) Toxic encephalopathy due to ingestion of bismuth salts: clinical and EEG studies of 45 patients. Journal of Neurology, Neurosurgery and Psychiatry, 40, 748–752.Google Scholar
Viterbo, V. S. Sicard, C. & Cathala, H. P. (1977) E. E. G. changes in 15 patients with bismuth encephalopathy. Electroencephalographie et Neuro-physiologie Clinique, 7, 139–146.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.