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Intranasal oxytocin increases covert attention to positive social cues

Published online by Cambridge University Press:  12 November 2012

G. Domes ,
M. Sibold ,
L. Schulze ,
A. Lischke ,
S. C. Herpertz  and
M. Heinrichs
G. Domes*
Affiliation:
Department of Psychology, University of Freiburg, Germany Freiburg Brain Imaging Center, University Medical Center, University of Freiburg, Germany
M. Sibold
Affiliation:
Department of Psychology, University of Freiburg, Germany
L. Schulze
Affiliation:
Department of Educational Sciences and Psychology, Freie Universität Berlin, Germany
A. Lischke
Affiliation:
Department of General Psychiatry, University of Heidelberg, Germany Department of Psychiatry and Psychotherapy, University of Rostock, Germany
S. C. Herpertz
Affiliation:
Department of Psychiatry and Psychotherapy, University of Rostock, Germany
M. Heinrichs
Affiliation:
Department of Psychology, University of Freiburg, Germany Freiburg Brain Imaging Center, University Medical Center, University of Freiburg, Germany
*
*Address for correspondence: G. Domes, Ph.D., Department of Psychology, Laboratory for Biological and Personality Psychology, University of Freiburg, Stefan-Meier-Strasse 8, D-79104 Freiburg, Germany. (Email: domes@psychologie.uni-freiburg.de)
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Abstract

Background

The neuropeptide oxytocin (OT) has positive effects on the processing of emotional stimuli such as facial expressions. To date, research has focused primarily on conditions of overt visual attention.

Method

We investigated whether a single intranasal dose of OT (24 IU) would modulate the allocation of attentional resources towards positive and negative facial expressions using a dot-probe paradigm in a sample of 69 healthy men. Attentional capacity for these facial cues was limited by presentation time (100 or 500 ms). In addition, we controlled for overt visual attention by recording eye movements using a remote eye tracker.

Results

Reaction times (RTs) in the dot-probe paradigm revealed a pronounced shift of attention towards happy facial expressions presented for 100 ms after OT administration, whereas there were no OT-induced effects for longer presentation times (500 ms). The results could not be attributed to modulations of overt visual attention as no substance effects on gazes towards the facial target were observed.

Conclusions

The results suggest that OT increased covert attention to happy faces, thereby supporting the hypothesis that OT modulates early attentional processes that might promote prosocial behavior.

Keywords

Attentionawarenesseye trackingfacial emotionsneuropeptidesoxytocin
Type
Original Articles
Information
Psychological Medicine , Volume 43 , Issue 8 , August 2013 , pp. 1747 - 1753
Copyright
Copyright © Cambridge University Press 2012 

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