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52 results in Hematology

Page 1 of 3

Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies
  • 2nd edition
  • Edited by Anna Porwit, Marie Christine Béné
  • Published online:
    30 January 2025
    Print publication:
    20 February 2025
  • Master the implementation of flow cytometry techniques in diagnosing complex hematologic diseases and malignancies in patients with this comprehensive and practical guide. Featuring updated recommendations on pre-analytical steps, instrument settings and panel construction, this manual offers invaluable support for those diagnosing, treating and researching hematologic malignancies. Written by leading experts in the field, this book puts flow cytometry into everyday context. Through engaging with differential diagnoses, the manual offers an accurate description of specific features of malignancies and mimicking conditions. It also places flow cytometry in the scope of integrated diagnosis according to WHO and ICC classifications. Fully updated throughout, this second edition provides new literature and concepts, and presents new AI-based analytical methods. Richly illustrated and in full colour, this book is an ideal resource for those working in flow cytometry laboratories.

Pediatric Pathology of Hematopoietic and Histiocytic Disorders
  • Edited by Xiayuan Liang, Bradford Siegele, Jennifer Picarsic
  • Published online:
    25 January 2024
    Print publication:
    15 February 2024
  • The presentation of hematolymphoid and histiocytic diseases can vary widely between children and adults as can age-related differential diagnoses and the consequences of treatment. Providing up to date information and classification for diseases across the hematopoietic, lymphoid and histiocytic systems, the book also covers morphologic, immunophenotypic, cytogenetic, and molecular genetic features of routine and diagnostically challenging disorders in pediatric patients. Over 200 high-quality colour illustrations aid accurate diagnosis and correct interpretations when evaluating peripheral blood, bone marrow, lymph nodes and other tissues specimens. This comprehensive yet practical guide also discusses useful ancillary tests and introduces newly recognised entities identified in the current literature, such as GATA-2 haploinsufficiency, B-ALL with DUX4-IGH and ERG deletion, and ALK-positive histiocytosis. An online version of the book with expandable figures can be accessed on Cambridge Core, via the code printed on the inside of the cover.

Atlas of Pediatric Hematopathology
  • Edited by Silvia Tse Bunting, Xiayuan Liang, Michele E. Paessler, Satheesh Chonat
  • Published online:
    25 November 2023
    Print publication:
    13 July 2023
  • Illustrated with over 800 colour images, this practical guide covers the unique morphology and disease spectrum in pediatric patients, ranging from normal physiologic changes to pathologic states. In addition, it covers newly described pediatric diseases, such as GATA-2 haploinsufficiency and reflects the latest WHO classification for hematolymphoid neoplasms. With the visual format of an atlas, the book provides a quick reference for trainees and physicians in hematopathology, as well as for hematologists and oncologists treating pediatric patients. An online version of the book with expandable figures can be accessed on Cambridge Core, via the code printed on the inside of the cover.

Neonatal Hematology
  • Pathogenesis, Diagnosis, and Management of Hematologic Problems
  • 3rd edition
  • Edited by Pedro A. de Alarcón, Eric J. Werner, Robert D. Christensen, Martha C. Sola-Visner
  • Published online:
    30 January 2021
    Print publication:
    18 February 2021
  • Neonatal hematology is a fast-growing field, and the majority of sick neonates will develop hematological problems. This is an essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values. Chapters have been thoroughly revised according to the latest advances in the field for this updated third edition. Topics discussed include erythrocyte disorders, platelet disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Coverage of oncological issues has been expanded to two separate chapters on leukemia and solid tumors, making information more easily accessible. Approaches to identifying the cause of anemia in a neonate are explained, with detailed algorithms provided to aid clinicians in practice. Covering an important hematologic niche with an ever increasing amount of specialized knowledge, this book is a valuable resource for hematologists, neonatologists and pediatricians.

Diagnostic Bone Marrow Haematopathology
  • Jon van der Walt, Attilio Orazi, Daniel A. Arber
  • Published online:
    12 November 2020
    Print publication:
    21 January 2021
  • Written by global experts, this indispensable guide includes over 200 illustrations and essential information in clear tabular formatting, giving hematopathologists rapid access to diagnostic criteria at the microscope. General principles of bone marrow biopsy and aspirate processing are covered, together with the normal and reactive bone marrow, infective, infiltrative and neoplastic diseases. Chapters also guide readers through the use of immunohistochemistry, flow cytometry and molecular diagnosis, whilst extensive referencing provides further reading in specialist and rare topics. Whether working as a generalist, specialist, trainee or resident, this in an essential bench guide for hematopathologists at all levels of experience. The print book comes with access to the text and expandable figures online at Cambridge Core, which can be accessed via the code printed on the inside of the cover.

Nutritional Anemia
  • Scientific Principles, Clinical Practice, and Public Health
  • Edited by Robert T. Means Jr
  • Published online:
    02 April 2019
    Print publication:
    11 April 2019
  • This major new comprehensive guide focuses on particular topics in the field of nutritional anemias, with in-depth coverage on each relevant nutrient whose deficiency can cause anemia, their metabolism, dietary requirements and related information. This book presents the unique hematological, and non-hematological, manifestations of each deficiency, the varied settings and causes of deficiency, interactions with other problems, diagnostic approaches and tools, synthesizing the perspectives of epidemiology, public health, and clinical hematology. Covering approaches to medical management in individuals, as well as in susceptible populations such as children, pregnant women and the elderly; and preventive strategies, such as supplementation and fortification, this exceptional text will appeal to a wide audience, from the clinician learning about the epidemiology and public health aspects of food fortification, to the public health practitioner who needs to understand clinical approaches to key nutritional anemia issues.

Anemia
  • Pathophysiology, Diagnosis, and Management
  • Edited by Edward J. Benz, Jr., Nancy Berliner, Fred J. Schiffman
  • Published online:
    18 April 2018
    Print publication:
    13 July 2017
  • In light of recent advances in scientific understanding, this textbook provides a comprehensive yet focused guide to anemia, the most common hematologic malady in medicine. This authoritative, clinical resource covers the scientific basis of the many forms of anemia, while offering a practical approach to prognosis, diagnosis and management. Chapters cover a multitude of topics, ranging from the basic components and physiologic functions, to secondary anemias and transfusion therapy. Modern in approach, this text also looks ahead to new and innovative methodologies. With recommended treatment plans and many case studies, this heavily-illustrated book is essential reading for hematologists and oncologists. In providing a pathophysiologic context, it is also of interest to nurse practitioners, physician assistants and medical students in the field. This book provides access to an online version on Cambridge Core, which can be accessed via the code printed on the inside of the cover.​

Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies
  • Edited by Anna Porwit, Marie Christine Béné
  • Published online:
    01 February 2018
    Print publication:
    25 January 2018
  • Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.

The Obstetric Hematology Manual
  • 2nd edition
  • Edited by Sue Pavord, Beverley Hunt
  • Published online:
    01 February 2018
    Print publication:
    08 February 2018
  • Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.

Hematopathology and Coagulation
  • Self-Assessment and Board Review
  • Amer Wahed, Jesse Manuel Jaso, Ashok Tholpady
  • Published online:
    19 July 2017
    Print publication:
    27 May 2017
  • A clear understanding of key areas in hematopathology, hematology and coagulation is essential for all trainees preparing to take their American Board of Pathology exams. This text offers a series of increasingly challenging multiple-choice questions and answers designed to help strengthen your knowledge. Question papers cover all areas of study, from red blood cell count and coagulation disorders to hematopoietic neoplasms. Each answer is accompanied by explanations and overviews of associated topics, enabling you to learn from mistakes and to revise effectively.

Hematopoietic Cell Transplants
  • Concepts, Controversies and Future Directions
  • Edited by Hillard M. Lazarus, Robert Peter Gale, Armand Keating, Andrea Bacigalupo, Reinhold Munker, Kerry Atkinson
  • Edited in association with Syed Ali Abutalib
  • Published online:
    24 May 2017
    Print publication:
    01 January 2000
  • This authoritative new book provides a comprehensive overview of diagnostic and therapeutic strategies in hematopoietic cell transplantation, explaining key concepts, successes, controversies and challenges. The authors and editors discuss current and future strategies for major challenges, such as graft-versus-host-disease, including new prophylaxis and treatments. They also discuss long-term complications, such as second malignancies and cardiovascular complications. Chapters are written by leading world experts, carefully edited to achieve a uniform and accessible writing style. Each chapter includes evidence-based explanations and state-of-the-art solutions, providing the reader with practice-changing advice. Full reference lists are also supplied to facilitate further exploration of each topic. Each copy of the printed book is packaged with a password, giving readers online access to all text and images. This inspiring resource demystifies both the basics and subtleties of hematopoietic cell transplantation, and is essential reading for both senior clinicians and trainees.

Pediatric Hematology
  • A Practical Guide
  • Robert Wynn, Rukhmi Bhat, Paul Monagle
  • Published online:
    23 February 2017
    Print publication:
    16 February 2017
  • Hematology is often considered a challenging subject by students and junior medical staff alike. Using key scientific and clinical principles, this succinct guide provides a summary of modern day-to-day clinical practice in paediatric hematology. Focusing on the facts that underpin patient management, each chapter offers an initial summary of a particular paediatric hematologic condition. Several key clinical scenarios set out how common difficulties should be managed, from the neonate with line thrombosis, to the newly presenting patient with leukaemia, and the child who has suffered a stroke. Covering all hematology topics on the syllabus of the American Board of Paediatrics subspecialty examinations, this authoritative guide is ideal for both postgraduates and junior doctors, whose understanding of hematological conditions will increase greatly upon reading. This comprehensive and practical book specifically aims to equip clinicians to diagnose and manage children with hematological illness, and to support them and their families.

Managing Myeloproliferative Neoplasms
  • A Case-Based Approach
  • Edited by Ruben A. Mesa, Claire N. Harrison
  • Published online:
    05 March 2016
    Print publication:
    31 March 2016
  • This is a concise, practical, case-based book documenting examples and scenarios that will help you manage challenging clinical issues for patients with myeloproliferative neoplasms. The editors and authors have strived to distil the very latest information in this rapidly advancing field in a way that will help you to update your practice and manage your patients. The key focuses are: diagnosis, both standard and challenging; both day-to-day management as well as special situations such as surgery, thrombotic events and pregnancy; and finally, managing evolving situations with MPN such as progression to acute myeloid leukemia. This book is an outstanding resource that includes a discussion of both classical myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera and myelofibrosis, and also less common disorders such as systemic mast cell disease, hypereosinophilia, MPN/MBS overlap syndromes and atypical CML, amongst others. This book is a practical reference for practitioners, hematologists, medical oncologists and trainees.

Molecular Oncology
  • Causes of Cancer and Targets for Treatment
  • Edited by Edward P. Gelmann, Charles L. Sawyers, Frank J. Rauscher, III
  • Published online:
    05 February 2015
    Print publication:
    19 December 2013
  • The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target.

Pediatric Thrombotic Disorders
  • Edited by Neil A. Goldenberg, Marilyn J. Manco-Johnson
  • Published online:
    18 December 2014
    Print publication:
    08 January 2015
  • This comprehensive and authoritative text summarizes current evidence and provides experienced perspectives on the etiology, diagnosis, and management of pediatric thrombotic disorders, including arterial ischemic stroke and cerebral sinovenous thrombosis. Authored by leaders in the field, individual chapters are devoted to specific anatomic sites and types of thrombosis. State-of-the-art, pediatric-focused chapters aid in diagnostic evaluation and therapeutic decision making, in settings ranging from the most routine to the most complex and challenging patient scenarios. Topics include: extremity and caval deep venous thrombosis; pulmonary embolism; cancer-associated thromboembolism; infection-associated thromboembolism; arterial ischemic stroke; cerebral sinovenous thrombosis; gastrointestinal and visceral thrombosis; developmental hemostasis; thrombophilias; heparin-induced thrombocytopenia/thrombosis syndrome; venous thromboembolism prevention; thrombolysis; and novel anticoagulants, among others. This text is a 'must-have' for practitioners in pediatric hematology, oncology, hematopoietic stem cell transplantation, neurology, hospital medicine, and intensive care.

Myeloma
  • Pathology, Diagnosis, and Treatment
  • Edited by Stephen A. Schey, Kwee L. Yong, Robert Marcus, Kenneth C. Anderson
  • Published online:
    18 December 2013
    Print publication:
    05 December 2013
  • Myeloma is the second-most common hematologic cancer, accounting for approximately 1 percent of all cancers and 2 percent of all deaths from cancer. In recent years there have been major and significant advances in the diagnosis, imaging, molecular pathogenesis, and therapy of myeloma. This book describes these advances in a single, practical volume, placing them in the context of daily clinical practice. Different myeloma subtypes are discussed in individual chapters, integrating etiology, pathogenesis, molecular pathology, histology, and therapy in a single place for each condition. The book begins by discussing epidemiology, imaging techniques, pathogenesis, and other general considerations. Conditions covered in detail include multiple myeloma, POEMS syndrome, Castleman's syndrome, Waldenstrom's macroglobulinemia, amyloidosis and MGUS. Featuring color illustrations, and written and edited by leading authorities in the field, Myeloma provides readers with the information they need to diagnose and manage these complex disorders.

Lymphoma
  • Pathology, Diagnosis, and Treatment
  • 2nd edition
  • Edited by Robert Marcus, John W. Sweetenham, Michael E. Williams
  • Published online:
    18 December 2013
    Print publication:
    05 December 2013
  • Major advances have occurred in the diagnosis and treatment of lymphoma in recent years. Our understanding of the molecular biology and genetics of the disease has increased exponentially, and significant imaging developments have resulted in earlier and more accurate diagnosis. The new edition of this landmark text places these advances in the context of daily clinical practice. Each chapter has been updated to reflect recent developments, including new treatment agents such as immunomodulatory drugs and the next generation of antibodies, and the increasing prognostic role of PET scanning. Results from recent large-scale clinical trials are presented, and pathology and cytogenetics are integrated into discussion of each disease entity, enabling the reader to review all the key diagnostic information in one place. Featuring many color illustrations, and written and edited by leading authorities in the field, Lymphoma provides all the information you need to diagnose and manage these complex disorders.

Manual of Stem Cell and Bone Marrow Transplantation
  • 2nd edition
  • Joseph H. Antin, Deborah Yolin Raley
  • Published online:
    05 November 2013
    Print publication:
    17 October 2013
  • Fully revised throughout, the second edition of Manual of Stem Cell and Bone Marrow Transplantation is based on the in-house handbook used at the world-renowned Dana-Farber Cancer Institute. It is a practical pocket manual for all members of the stem cell and bone marrow transplant team. Written by experts at Dana-Farber, the contents are handily arranged in outline format for maximum usefulness and convenience. This essential and user-friendly manual covers all aspects of the transplantation process, from stem cell processing through management of transplant-related complications. Topics discussed thoroughly include evaluation and counselling of patients and donors, preventative care, graft-versus-host disease and conditioning regimens. A new extensive chapter on oral health in stem cell transplantation has been added. These features make the Manual of Stem Cell and Bone Marrow Transplantation an ideal resource for the entire transplant team.

The BMT Data Book
  • Including Cellular Therapy
  • 3rd edition
  • Edited by Reinhold Munker, Gerhard C. Hildebrandt, Hillard M. Lazarus, Kerry Atkinson
  • Published online:
    05 August 2013
    Print publication:
    21 February 2013
  • This is an essential guide to the data, basic science, outcome studies and decision-making processes involved in blood and marrow stem cell transplantation. Organized according to disease types and procedures, it contains more than 100 tables, figures and algorithms that reflect up-to-date research and give guidance on the choices between different types of chemotherapy, autologous vs. allogeneic transplantation, peripheral blood vs. bone marrow stem cells, and standard vs. experimental treatments. This new edition summarizes the research of the last four years and gives mature data for all established indications, such as acute myeloid leukemia, myelodysplastic syndrome and Hodgkin and non-Hodgkin lymphomas. New chapters discuss global trends in stem cell transplantation, cellular therapies including donor lymphocytes, and pediatric neurologic and metabolic disorders. With an expanded complications section, links to electronic databases and discussion of new drugs and alternative stem cell sources, this text belongs in every transplant unit.

Childhood Leukemias
  • 3rd edition
  • Edited by Ching-Hon Pui
  • Published online:
    05 April 2013
    Print publication:
    21 June 2012
  • New insights into the molecular biology of childhood leukemias have stimulated numerous advances in diagnostic methods, strategies for risk assessment and the development of novel therapy for genetic subtypes of the diseases. Fully revised and updated, this new edition of Childhood Leukemias provides the most comprehensive, clinically-oriented and authoritative reference dedicated to these diseases. Beginning with an overview of history, cell biology, and pathology, subsequent chapters review approaches in the evaluation and management of specific leukemias, new therapeutic development and the unique pharmacodynamics and pharmacogenetics of individual patients. New chapters include epigenetics of leukemias, leukemias in patients with Down syndrome and leukemia in adolescents and young adults. The final section covers the complications associated with the disease or its treatment and supportive care during and after treatment. Authored by leading experts, this is a 'must-have' for any physician or investigator who deals with leukemias in childhood.

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