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56 results in Biotechnology

Page 1 of 3

Bioprocesses
  • A Comprehensive Guide to Sustainable Resources in the Non-Fossil Era
  • Edited by Sven Gjedde Sommer, Morten Lykkegaard Christensen, Birgir Norddahl, Morten Ambye-Jensen, Maria Cinta Roda-Serrat
  • Published online:
    24 January 2025
    Print publication:
    13 February 2025
  • In the rapidly evolving landscape of sustainable energy and resource management, this book is an indispensable resource for students, researchers, and professionals alike. Written by leading experts in the field, it delves into the multifaceted realm of biomass, positioning it as the cornerstone of a non-fossil future. After navigating through the fundamentals, this book discusses the diverse forms of biomass and its use as a renewable and environmentally friendly resource. From the intricacies of biomass production, conversion technologies, and utilization methods, to the economic and ecological implications, each chapter provides a meticulous exploration of key concepts and cutting-edge developments. Questions are posed throughout as well as more than 80 end-of-chapter exercises to gauge reader understanding and translate knowledge to real-world problem solving. Focusing on practicality and real-world applications, this resource not only educates but inspires a shift toward sustainable practices guiding the next generation toward a greener, more sustainable future.

An Introduction to Genetic Engineering
  • 4th edition
  • Desmond S. T. Nicholl
  • Published online:
    10 February 2023
    Print publication:
    02 March 2023
  • The fourth edition of this popular textbook retains its focus on the fundamental principles of gene manipulation, providing an accessible and broad-based introduction to the subject for beginning undergraduate students. It has been brought thoroughly up to date with new chapters on the story of DNA and genome editing, and new sections on bioethics, significant developments in sequencing technology and structural, functional and comparative genomics and proteomics, and the impact of transgenic plants. In addition to chapter summaries, learning objectives, concept maps, glossary and key word lists the book now also features new concluding sections, further reading lists and web-search activities for each chapter to provide a comprehensive suite of learning resources to help students develop a flexible and critical approach to the study of genetic engineering.

Commercializing Successful Biomedical Technologies
  • 2nd edition
  • Shreefal S. Mehta
  • Published online:
    03 November 2022
    Print publication:
    17 November 2022
  • Transform your research into commercial biomedical products with this revised and updated second edition. Covering drugs, devices and diagnostics, this book provides a step-by-step introduction to the process of commercialization, and will allow you to create a realistic business plan to develop your ideas into approved biomedical technologies. This new edition includes: Over 25% new material, including practical tips on startup creation from experienced entrepreneurs. Tools for starting, growing and managing a new venture, including business planning and commercial strategy, pitching investors, and managing operations.Global real-world case studies, including emerging technologies such as regulated medical software and Artificial Intelligence (AI), offer insights into key challenges and help illustrate complex points. Tips and operational tools from established industry insiders, suitable for graduate students and new biomedical entrepreneurs.

Fundamentals of Nanomedicine
  • James F. Leary
  • Published online:
    08 March 2022
    Print publication:
    31 March 2022
  • The first introductory book on the subject, this book will provide a complete grounding to this pioneering field for students and professionals across biomedical engineering, biology and medicine. It features a comprehensive overview of original work in this revolutionary field. Topics discussed include drug delivery, cell-material interaction and gene therapy, accompanied by real-world examples and over 100 illustrations. The book teaches readers how to design and test their own nanomedical systems for real-world applications in biomedical engineering, medicine and pharmacy. Presenting a thorough discussion of the science and engineering of nanomedicine, it discusses vital environmental, social and ethical impacts of this revolutionary technology. Including over 200 thought-provoking study questions, allowing the reader to self-assess their understanding, this book is a rich source of information that will be of interest and importance in nanomedicine.

Practical Techniques in Molecular Biotechnology
  • Bal Ram Singh, Raj Kumar
  • Published online:
    15 October 2021
    Print publication:
    16 June 2022
  • Practical Techniques in Molecular Biotechnology intends to familiarise students with the basics of the well-known experiments of molecular biotechnology and related courses like chemical biotechnology and cell biology. The content of the book will be useful in strengthening the basic skills and help students to apply the concepts to real-world problems. This book emphasises important concepts like bioanalytical techniques, biochemical analysis of proteins, recombinant DNA, and protein technology etc. The text will help students to understand the theoretical aspects of the techniques and provide experience with hands-on techniques to demonstrate practical troubleshooting and data analysis. The text is supported with diagrams, data, summaries for the quick recap and appendices with useful protocols and calculation methods.

Bionanotechnology
  • Concepts and Applications
  • Ljiljana Fruk, Antonina Kerbs
  • Published online:
    04 March 2021
    Print publication:
    04 February 2021
  • Connecting theory with real-life applications, this is the first ever textbook to equip students with a comprehensive knowledge of all the key concepts in bionanotechnology. By bridging the interdisciplinary gap from which bionanotechnology emerged, it provides a systematic introduction to the subject, accessible to students from a wide variety of backgrounds. Topics range from nanomaterial preparation, properties and biofunctionalisation, and analytical methods used in bionanotechnology, to bioinspired and DNA nanotechnology, and applications in biosensing, medicine and tissue engineering. Throughout the book, features such as 'Back to basics' and 'Research report' boxes enable students to build a strong theoretical knowledge and to link this to practical applications and up-to-date research. With over 200 detailed, full-colour illustrations and more than 100 end-of-chapter problems, this is an essential guide to bionanotechnology for any student studying this exciting, fast-developing and interdisciplinary field.

Prokaryotic Metabolism and Physiology
  • 2nd edition
  • Byung Hong Kim, Geoffrey Michael Gadd
  • Published online:
    04 May 2019
    Print publication:
    16 May 2019
  • Vast numbers of different prokaryotic microorganisms shape the biosphere, with diverse metabolic capabilities. Determination of genome sequences for a wide range of bacteria and archaea now requires an in-depth knowledge of prokaryotic metabolic function to give biochemical, physiological and ecological meaning to the genomic information. This new edition describes up-to-date knowledge of the key metabolic processes that occur under different conditions, and the cellular processes that determine prokaryotic roles in the environment, biotechnology and human health. Essential for students of microbiology, applied microbiology, biotechnology, genomics and systems biology, this advanced textbook covers prokaryotic structure, composition, nutrient transport, biosynthesis and growth. Newly characterised metabolic pathways are included, as well as the latest understanding of metabolic regulation and stress responses. Additionally, the link between energetics, growth and survival is discussed as well as the maintenance of genetic integrity by the bacterial immune system.

Biomedical Engineering
  • Bridging Medicine and Technology
  • 2nd edition
  • W. Mark Saltzman
  • Published online:
    28 May 2018
    Print publication:
    21 May 2015
  • The second edition of this popular introductory undergraduate textbook uses examples, applications, and profiles of biomedical engineers to show students the relevance of the theory and how it can be used to solve real problems in human medicine. The essential molecular biology, cellular biology, and human physiology background is included for students to understand the context in which biomedical engineers work. Updates throughout highlight important advances made over recent years, including iPS cells, microRNA, nanomedicine, imaging technology, biosensors, and drug delivery systems, giving students a modern description of the various subfields of biomedical engineering. Over two hundred quantitative and qualitative exercises, many new to this edition, help consolidate learning, whilst a solutions manual, password-protected for instructors, is available online. Finally, students can enjoy an expanded set of leader profiles in biomedical engineering within the book, showcasing the broad range of career paths open to students who make biomedical engineering their calling.

Dynamics of Engineered Artificial Membranes and Biosensors
  • William Hoiles, Vikram Krishnamurthy, Bruce Cornell
  • Published online:
    25 May 2018
    Print publication:
    03 May 2018
  • Learn about the state of the art in building artificial membranes and synthetic biological devices, and in constructing mathematical models for their dynamics at multiple time and spatial scales with this comprehensive book. Drawing on recent advances in bioengineering and biochemistry, it describes how to engineer tethered bilayer lipid membranes, bioelectronic interfaces, high-resolution biosensors, and diagnostic devices for non-invasive cellular measurements and electroporation. Multi-physics models combining atomistic (molecular dynamics and coarse-grained molecular dynamics), mesoscopic (Poisson–Nernst–Planck), and macroscopic (reaction-rate theory) dynamics provide a complete structure-to-function description of these devices. Experiments and dynamic models explain how anti-microbial peptides penetrate membranes, how molecular machine biosensors built out of artificial membranes can detect femtomolar concentrations, and how electroporation can be controlled. Supported by atomistic simulation code online, this is essential reading for researchers, students and professionals in bioengineering, chemical engineering, biophysics, applied mathematics, and electrical engineering.

Modern Prometheus
  • Editing the Human Genome with Crispr-Cas9
  • Jim Kozubek
  • Published online:
    19 April 2018
    Print publication:
    26 April 2018
  • Would you change your genes if you could? As we confront the 'industrial revolution of the genome', the recent discoveries of Crispr-Cas9 technologies are offering, for the first time, cheap and effective methods for editing the human genome. This opens up startling new opportunities as well as significant ethical uncertainty. Tracing events across a fifty-year period, from the first gene splicing techniques to the present day, this is the story of gene editing - the science, the impact and the potential. Kozubek weaves together the fascinating stories of many of the scientists involved in the development of gene editing technology. Along the way, he demystifies how the technology really works and provides vivid and thought-provoking reflections on the continuing ethical debate. This updated paperback edition contains all the very latest on the patent battle over Crisp and the applications of Crispr technology in agriculture and medicine.

Genetically Modified Organisms in Developing Countries
  • Risk Analysis and Governance
  • Edited by Ademola A. Adenle, E. Jane Morris, Denis J. Murphy
  • Published online:
    05 July 2017
    Print publication:
    09 June 2017
  • Bringing together the ideas of experts from around the world, this incisive text offers cutting-edge perspectives on the risk analysis and governance of genetically modified organisms (GMOs), supporting effective and informed decision-making in developing countries. Comprised of four comprehensive sections, this book covers: integrated risk analysis and decision making, giving an overview of the science involved and examining risk analysis methods that impact decision-making on the release of GMOs, particularly in developing countries; diversification of expertise involved in risk analysis and practical ways in which the lack of expertise in developing countries can be overcome; risk analysis based regulatory systems and how they can be undermined by power relationships and socio-political interests, as well as strategies for improving GMO policy development and regulatory decision-making; and case studies from developing countries providing lessons based on real-world experience that can inform our current thinking.

Optogenetics
  • From Neuronal Function to Mapping and Disease Biology
  • Edited by Krishnarao Appasani
  • Published online:
    28 April 2017
    Print publication:
    27 April 2017
  • Discovered little more than a decade ago, optogenetics - a revolutionary technique combining genetic and optical methods to observe and control the function of neurons - is now a widely used research tool. Optogenetics-driven research has led to insights into Parkinson's disease and other neurological and psychiatric disorders. With contributions from leaders and innovators from both academia and industry, this volume explores the discovery and application of optogenetics, from the basic science to its potential clinical use. Chapters cover a range of optogenetics applications, including for brain circuits, plasticity, memory, learning, sleep, vision and neurodegenerative and neuropsychiatric diseases. Providing authoritative coverage of the huge potential that optogenetics research carries, this is an ideal resource for researchers and graduate students, as well as for those working in the biotechnology and pharmaceutical industries and in a clinical setting.

Modern Prometheus
  • Editing the Human Genome with Crispr-Cas9
  • James Kozubek
  • Published online:
    20 October 2016
    Print publication:
    18 October 2016
  • Would you change your genes if you could? As we confront the 'industrial revolution of the genome', the recent discoveries of Crispr-Cas9 technologies are offering, for the first time, cheap and effective methods for editing the human genome. This opens up startling new opportunities as well as significant ethical uncertainty. Tracing events across a fifty-year period, from the first gene splicing techniques to the present day, this is the story of gene editing - the science, the impact and the potential. Kozubek weaves together the fascinating stories of many of the scientists involved in the development of gene editing technology. Along the way, he demystifies how the technology really works and provides vivid and thought-provoking reflections on the continuing ethical debate. Ultimately, Kozubek places the debate in its historical and scientific context to consider both what drives scientific discovery and the implications of the 'commodification' of life.

Governing Digitally Integrated Genetic Resources, Data, and Literature
  • Global Intellectual Property Strategies for a Redesigned Microbial Research Commons
  • Jerome H. Reichman, Paul F. Uhlir, Tom Dedeurwaerdere
  • Published online:
    05 May 2016
    Print publication:
    19 May 2016
  • The free exchange of microbial genetic information is an established public good, facilitating research on medicines, agriculture, and climate change. However, over the past quarter-century, access to genetic resources has been hindered by intellectual property claims from developed countries under the World Trade Organization's TRIPS Agreement (1994) and by claims of sovereign rights from developing countries under the Convention on Biological Diversity (CBD) (1992). In this volume, the authors examine the scientific community's responses to these obstacles and advise policymakers on how to harness provisions of the Nagoya Protocol (2010) that allow multilateral measures to support research. By pooling microbial materials, data, and literature in a carefully designed transnational e-infrastructure, the scientific community can facilitate access to essential research assets while simultaneously reinforcing the open access movement. The original empirical surveys of responses to the CBD included here provide a valuable addition to the literature on governing scientific knowledge commons.

In Defense of Pluralism
  • Policy Disagreement and its Media Coverage
  • Éric Montpetit
  • Published online:
    05 March 2016
    Print publication:
    07 April 2016
  • The work of early pluralist thinkers, from Arthur Bentley to Robert Dahl, inspired much optimism about democracy. They argued that democracy was functioning well, despite disagreements arising among the diversity of interests represented in policy-making processes. Yet it is unlikely that anyone paying attention to news coverage today would share such optimism. The media portray current policy-making processes as intractably polarized, devoid of any opportunity to move forward and adopt essential policy changes. This book aims to revive our long-lost sense of optimism about policy-making and democracy. Through original research into biotechnology policy-making in North America and Europe, Éric Montpetit shows that the depiction of policy-making offered by early pluralist thinkers is not so far off the present reality. Today's policy decision-making process - complete with disagreement among the participants - is consistent with what might be expected in a pluralist society, in sharp contrast with the negative image projected by the media.

Bioinformatics and Computational Biology in Drug Discovery and Development
  • Edited by William T. Loging
  • Published online:
    05 February 2016
    Print publication:
    17 March 2016
  • Computational biology drives discovery through its use of high-throughput informatics approaches. This book provides a road map of the current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through the use of previously unpublished, real-life case studies the impact of a range of computational approaches are discussed at various phases of the pipeline. Additionally, a focus section provides innovative visualisation approaches, from both the drug discovery process as well as from other fields that utilise large datasets, recognising the increasing use of such technology. Serving the needs of early career and more experienced scientists, this up-to-date reference provides an essential introduction to the process and background of drug discovery, highlighting how computational researchers can contribute to that pipeline.

Chromatographic Processes
  • Modeling, Simulation, and Design
  • Roger-Marc Nicoud
  • Published online:
    05 April 2015
    Print publication:
    20 April 2015
  • Addressing all aspects of the design, modeling and simulation of chromatographic processes, this result-oriented primer provides a practical guide to all the necessary approaches, methodologies and tools. Beginning with key definitions and concepts, it builds up from the most simple to the most complex situations, including multicomponent systems, non-uniform velocity profiles, bed instability, particle size distributions, and the influence of complex environments on chromatographic process design. In addition to covering classical approaches, it introduces efficient tools for investigating chromatographic processes, such as the 'Russian-Lego' approach for linear systems, phenomenological models, and specific shortcuts for deriving the key properties of industrial processes. With an emphasis on real-world problems and applications, step-by step modeling design guidelines, and detailed exercises for self-assessment, this is a must-have guide for practitioners and researchers working in chemical, biochemical, food and pharmaceutical engineering.

Genetic Mapping in Experimental Populations
  • J. W. Van Ooijen, J. Jansen
  • Published online:
    05 August 2013
    Print publication:
    08 August 2013
  • Genetic linkage maps are an increasingly important tool in both fundamental and applied research, enabling the study and deployment of genes that determine important biological traits. This concise introduction to genetic mapping in species with disomic inheritance enables life science graduate students and researchers to use mapping software to produce more reliable results. After a brief refresher on meiosis and genetic recombination, the steps in the map construction procedure are described, with explanations of the computations involved. The emphasis throughout is on the practical application of the methods described; detailed mathematical formulae are avoided and exercises are included to help readers consolidate their understanding. A chapter on recognising and solving problems provides valuable guidance for dealing with real-life situations. An extensive chapter dedicated to the more complex situation of outbreeding species offers a unique insight into the approach required for many economically important and model species, both plants and animals.

Regenerative Pharmacology
  • Edited by George J. Christ, Karl-Erik Andersson
  • Published online:
    05 April 2013
    Print publication:
    15 April 2013
  • Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.

Successful Agricultural Innovation in Emerging Economies
  • New Genetic Technologies for Global Food Production
  • Edited by David J. Bennett, Richard C. Jennings
  • Published online:
    05 March 2013
    Print publication:
    07 March 2013
  • World population is forecast to grow from 7 to 9 billion by 2050, 1 in 6 is already hungry and food production must increase by 70-100% if it is to feed this growing population. No single solution will solve this problem but recent developments in the genetic technologies of plant breeding can help to increase agricultural efficiencies and save people from hunger in a sustainable manner, particularly in African nations where the need is greatest. These advances can rapidly incorporate new traits and tailor existing crops to meet new requirements and also greatly reduce the time and costs taken to improve local crop varieties. This book provides a collected, reliable, succinct review which deals expressly with the successful implementation of the new plant genetic sciences in emerging economies in the context of the interrelated key regulatory, social, ethical, political and trade matters.

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