Nezhat's Textbook of Minimally Invasive Surgery Published online by Cambridge University Press: 06 November 2025
One of the most significant advancements in modern medicine has been the shift away from large incision “open” surgeries to video-assisted endoscopy, a groundbreaking innovation invented and pioneered by Camran Nezhat, MD, in the late 1970s.[1–4] Initially referred to as “keyhole,” “Band-Aid,” video surgery, or video laparoscopy, video-assisted endoscopy and video-assisted thoracoscopy (VAT) are now universally referred to as “minimally invasive surgery” (MIS), with or without robotic assistance. Dismissed as a barbaric and dangerous gimmick just 30 years ago, today MIS is recognized for profoundly improving the health outcomes of hundreds of millions of patients around the world. Indeed, with countless lives saved and millions of hospitalizations and surgery-related permanent disabilities prevented, the transformative impact that MIS has had on patients has been so remarkable that it has been described as a change to surgery as revolutionary for our era as anesthesia was for the nineteenth century.
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