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    • Publisher:
      Cambridge University Press
      Publication date:
      September 2010
      June 1988
      ISBN:
      9780511753183
      9780521105897
      Dimensions:
      Weight & Pages:
      Dimensions:
      (229 x 152 mm)
      Weight & Pages:
      0.36kg, 244 Pages
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    Book description

    First published in 1988, this volume surveys the chemical synthesis and biological activity of the benz[a]anthracenes. These compounds occur in smoke and mineral oils and a few have been shown to be potent carcinogens. This volume was the first to review, systematically and in depth, the organic synthesis of these compounds as well as their metablolism, interactions with nucleic acids and protein, mutagenicity and carcinogenicity. Such studies have important implications in determining mechanism and specificity of chemically induced carcinogenesis.

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