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Section 3 - Major HAI Categories: Surveillance and Prevention

Published online by Cambridge University Press:  02 April 2018

Ebbing Lautenbach
Affiliation:
University of Pennsylvania School of Medicine
Preeti N. Malani
Affiliation:
University of Michigan, Ann Arbor
Keith F. Woeltje
Affiliation:
Washington University School of Medicine, St Louis
Jennifer H. Han
Affiliation:
University of Pennsylvania School of Medicine
Emily K. Shuman
Affiliation:
University of Michigan, Ann Arbor
Jonas Marschall
Affiliation:
Washington University School of Medicine, St Louis
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Print publication year: 2018

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References

References

Centers for Disease Control and Prevention. Catheter-associated Urinary Tract Infections (CAUTI). www.cdc.gov/HAI/ca_uti/uti.html. Accessed October 1, 2015.Google Scholar
Saint, S, Chenoweth, CE. Biofilms and catheter-associated urinary tract infections. Infect Dis Clin North Am 2003;17: 411432.CrossRefGoogle ScholarPubMed
Tambyah, PA, Halvorson, KT, Maki, DG. A prospective study of pathogenesis of catheter-associated urinary tract infections. Mayo Clin Proc 1999;74: 131136.CrossRefGoogle ScholarPubMed
Maki, DG, Tambyah, PA. Engineering out the risk of infection with urinary catheters. Emerging Infect Dis 2001;7(2): 16.CrossRefGoogle ScholarPubMed
Magill, SS, Edwards, JR, Bamberg, W, et al. Multistate point-prevalence survey of healthcare-associated infections, 2011. N Engl J Med 2014;370: 11981208.10.1056/NEJMoa1306801CrossRefGoogle Scholar
Dudeck, MA, Weiner, LM, Allen-Bridson, K, et al. National Healthcare Safety Network (NHSN) report, data summary for 2012, device-associated module. Am J Infect Control 2013;41: 11481166.10.1016/j.ajic.2013.09.002CrossRefGoogle ScholarPubMed
Langley, JM, Hanakowski, M, LeBlanc, JC. Unique epidemiology of nosocomial urinary tract infection in children. Am J Infect Control 2001;29: 9498.CrossRefGoogle ScholarPubMed
Centers for Disease Control and Prevention. Urinary tract infection (catheter-associated urinary tract infection [CAUTI] and non-catheter-associated urinary tract infection [UTI]) and other urinary tract system (USI) events. Available at: www.cdc.gov/nhsn/PDFs/pscManual/7pscCAUTIcurrent.pdf. Accessed February 1, 2016.Google Scholar
Tambyah, PA, Maki, DG. Catheter-associated urinary tract infection is rarely symptomatic: a prospective study of 1,497 catheterized patients. Arch Intern Med 2000;160(5): 678682.Google ScholarPubMed
Sievert, DM, Ricks, P, Edwards, JR, et al. Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009–2010. Infect Control Hosp Epidemiol 2013;34(1): 114.10.1086/668770CrossRefGoogle Scholar
Platt, R, Polk, BF, Murdock, B, Rosner, B. Risk factors for nosocomial urinary tract infection. Am J Epidemiol 1986;124(6): 977.10.1093/oxfordjournals.aje.a114487CrossRefGoogle ScholarPubMed
Greene, MT, Chang, R, Kuhn, L, et al. Predictors of hospital-acquired urinary tract-related bloodstream infection. Infect Control Hosp Epidemiol 2012;33(10): 10011007.CrossRefGoogle ScholarPubMed
Musher, DM, Thorsteinsson, SB, Airola, VW II. Quantitative urinalysis: diagnosing urinary tract infection in men. JAMA 1976;236: 20692072.10.1001/jama.1976.03270190025022CrossRefGoogle ScholarPubMed
Biering-Sorenson, F, Bagi, P, Hoiby, N. Urinary tract infections in patients with spinal cord lesions: treatment and prevention. Drugs 2001;61(9): 12751287.CrossRefGoogle Scholar
Centers for Disease Control and Prevention. Healthcare facility HAI reporting requirements to CMS via NHSN – current or proposed requirements. Available at: www.cdc.gov/nhsn/pdfs/cms/cms-reporting-requirements.pdf. Accessed October 1, 2015.Google Scholar
Centers for Medicare and Medicaid Services. Hospital compare. Available at: www.medicare.gov/hospitalcompare/search.html. Accessed October 1, 2015.Google Scholar
Lo, E, Nicolle, LE, Coffin, SE, et al. Strategies to prevent catheter-associated urinary tract infection in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol 2014;35(S2): S32S47.CrossRefGoogle ScholarPubMed
Boyce, JM, Pittet, D. Guideline for hand hygiene in health-care settings: recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America. MMWR Recomm Rep 2002;51(RR-16): 145.Google ScholarPubMed
Siegel, JD, Rhinehart, E, Jackson, M, Chiarello, L. 2007 Guideline for isolation precautions: preventing transmission of infectious agents in health care settings. Am J Infect Control 2007;35(10 Suppl 2):S65S164.10.1016/j.ajic.2007.10.007CrossRefGoogle ScholarPubMed
Gandhi, T, Flanders, SA, Markovitz, E, Saint, S, Kaul, DR. Importance of urinary tract infection to antibiotic use among hospitalized patients. Infect Control Hosp Epidemiol 2009;30(2): 193195.CrossRefGoogle ScholarPubMed
Barlam, TF, Cosgrove, SE, Abbo, LM, et al. Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis 2016;62(10): e51e77.CrossRefGoogle Scholar
Gould, CV, Umscheid, CA, Agarwal, RK, Kuntz, G, Pegues, DA, HICPAC. Centers for Disease Control and Prevention. Guideline for prevention of catheter-associated urinary tract infections (draft). 2008. Available at: wwwn.cdc.gov/PUBLICCOMMENTS/comments/guidelines-for-prevention-of-catheter-associated-urinary-tract-infections-2008.aspx. Accessed August 30, 2009.Google Scholar
Nicolle, LE. The prevention of hospital-acquired urinary tract infection. Clin Infect Dis 2008;46(2): 251253.CrossRefGoogle ScholarPubMed
Gardam, MA, Amihod, B, Orenstein, P, Consolacion, N, Miller, MA. Overutilization of indwelling urinary catheters and the development of nosocomial urinary tract infections. Clin Perform Qual Health Care 1998;6(3): 99102.Google ScholarPubMed
Jain, P, Parada, JP, David, A, Smith, LG. Overuse of the indwelling urinary tract catheter in hospitalized medical patients. Arch Intern Med 1995;155(13): 14251429.10.1001/archinte.1995.00430130115012CrossRefGoogle ScholarPubMed
Munasinghe, RL, Yazdani, H, Siddique, M, Hafeez, W. Appropriateness of use of indwelling urinary catheters in patients admitted to the medical service. Infect Control Hosp Epidemiol 2001;22(10): 647649.10.1086/501837CrossRefGoogle Scholar
Conybeare, A, Pathak, S, Imam, I. The quality of hospital records of urethral catheterisation. Ann R Coll Surg Engl 2002;84(2): 109110.Google ScholarPubMed
Saint, S, Wiese, J, Amory, JK, et al. Are physicians aware of which of their patients have indwelling catheters? Am J Med 2000;109: 476480.CrossRefGoogle Scholar
Huang, WC, Wann, SR, Lin, SL, et al. Catheter-associated urinary tract infections in intensive care units can be reduced by prompting physicians to remove unnecessary catheters. Infect Control Hosp Epidemiol 2004;25(11): 974978.10.1086/502329CrossRefGoogle ScholarPubMed
Fakih, MG, Dueweke, C, Meisner, S, et al. Effect of nurse-led multidisciplinary rounds on reducing the unnecessary use of urinary catheterization in hospitalized patients. Infect Control Hosp Epidemiol 2008;29(9): 815819.CrossRefGoogle ScholarPubMed
Saint, S, Kaufman, SR, Thompson, M, Rogers, MA, Chenoweth CE. A reminder reduces urinary catheterization in hospitalized patients. Jt Comm J Qual Patient Saf 2005;31(8): 455462.Google ScholarPubMed
Cornia, PB, Amory, JK, Fraser, S, Saint, S, Lipsky, BA. Computer-based order entry decreases duration of indwelling urinary catheterization in hospitalized patients. Am J Med 2003;114(5): 404407.10.1016/S0002-9343(02)01568-1CrossRefGoogle ScholarPubMed
Wald, HL, Ma, A, Bratzler, DW, Kramer, AM. Indwelling urinary catheter use in the postoperative period: analysis of the national surgical infection prevention project data. Arch Surg 2008;143(6): 551557.CrossRefGoogle ScholarPubMed
Wald, HL, Epstein, AM, Radcliff, TA, Kramer, AM. Extended use of urinary catheters in older surgical patients: a patient safety problem? Infect Control Hosp Epidemiol 2008;29(2): 116124.10.1086/526433CrossRefGoogle ScholarPubMed
Stephan, F, Sax, H, Wachsmuth, M, Hoffmeyer, P, Clergue, F, Pittet, D. Reduction of urinary tract infection and antibiotic use after surgery: a controlled, prospective, before-after intervention study. Clin Infect Dis 2006;42(11): 15441551.10.1086/503837CrossRefGoogle ScholarPubMed
Niel-Weise, BS, van den Broek, PJ. Urinary catheter policies for short-term bladder drainage in adults. Cochrane Database Syst Rev 2005(3): CD004203.Google ScholarPubMed
Michelson, JD, Lotke, PA, Steinberg, ME. Urinary-bladder management after total joint-replacement surgery. N Engl J Med 1988;319(6): 321326.Google ScholarPubMed
Oishi, CS, Williams, VJ, Hanson, PB, Schneider, JE, Colwell, CW Jr, Walker, RH. Perioperative bladder management after primary total hip arthroplasty. J Arthroplasty 1995;10(6): 732736.10.1016/S0883-5403(05)80067-1CrossRefGoogle ScholarPubMed
Moore, DA, Edwards, K. Using a portable bladder scan to reduce the incidence of nosocomial urinary tract infections. Medsurg Nurs 1997;6(1): 3943.Google ScholarPubMed
Stevens, E. Bladder ultrasound: avoiding unnecessary catheterizations. Medsurg Nurs 2005;14(4): 249253.Google ScholarPubMed
Saint, S, Kaufman, SR, Rogers, MA, Baker, PD, Ossenkop, K, Lipsky, BA. Condom versus indwelling urinary catheters: a randomized trial. J Am Geriatr Soc 2006;54(7): 10551061.10.1111/j.1532-5415.2006.00785.xCrossRefGoogle ScholarPubMed
Saint, S, Lipsky, BA, Baker, PD, McDonald, LL, Ossenkop, K. Urinary catheters: what type do men and their nurses prefer? J Am Geriatr Soc 1999;47(12): 14531457.CrossRefGoogle ScholarPubMed
Guidelines for preventing infections associated with the insertion and management of short term indwelling urethral catheters in acute care. J Hosp Infect 2001;47(Suppl): S39S46.10.1053/jhin.2000.0890CrossRefGoogle Scholar
Webster, J, Hood, RH, Burridge, CA, Doidge, ML, Phillips, KM, George, N. Water or antiseptic for periurethral cleaning before urinary catheterization: a randomized controlled trial. Am J Infect Control 2001;29(6): 389394.CrossRefGoogle ScholarPubMed
Burke, JP, Garibaldi, RA, Britt, MR, Jacobson, JA, Conti, M, Alling, DW. Prevention of catheter-associated urinary tract infections: efficacy of daily meatal care regimens. Am J Med 1981;70(3): 655658.CrossRefGoogle ScholarPubMed
Saint, S, Lipsky, BA. Preventing catheter-related bacteriuria: should we? Can we? How? Arch Intern Med 1999;159(8): 800808.10.1001/archinte.159.8.800CrossRefGoogle Scholar
Tenney, JH, Warren, JW. Bacteriuria in women with long-term catheters: paired comparison of indwelling and replacement catheters. J Infect Dis 1988;157(1): 199202.CrossRefGoogle ScholarPubMed
Warren, JW, Platt, R, Thomas, RJ, Rosner, B, Kass, EH. Antibiotic irrigation and catheter-associated urinary-tract infections. N Engl J Med 1978;299(11): 570573.10.1056/NEJM197809142991103CrossRefGoogle ScholarPubMed
Saint, S, Elmore, J, Sullivan, S, Emerson, S, Koepsell, T. The efficacy of silver alloy-coated urinary catheters in preventing urinary tract infection: a meta-analysis. Am J Med 1998;105: 236241.10.1016/S0002-9343(98)00240-XCrossRefGoogle ScholarPubMed
Johnson, JR, Kuskowski, MA, Wilt, TJ. Systematic review: antimicrobial urinary catheters to prevent catheter-associated urinary tract infection in hospitalized patients. Ann Intern Med 2006;144(2): 116126.CrossRefGoogle ScholarPubMed
Jahn, P, Preuss, M, Kernig, A, Langer, G, Seifert-Huehmer, A. Types of indwelling urinary catheters for long-term bladder drainage in adults. Cochrane Database Syst Rev 2007(3): CD004997.Google ScholarPubMed

References

Magill, SS, Klompas, M, Balk, R, et al. Developing a new, national approach to surveillance for ventilator-associated events. Crit Care Med 2013;41: 24672475.10.1097/CCM.0b013e3182a262dbCrossRefGoogle ScholarPubMed
Klompas, M. Complications of mechanical ventilation: the CDC’s new surveillance paradigm. N Engl J Med 2013;368: 14721475.10.1056/NEJMp1300633CrossRefGoogle ScholarPubMed
Klein Klouwenberg, PM, Ong, DS, Bos, LD, et al. Interobserver Agreement of Centers for Disease Control and Prevention Criteria for Classifying Infections in Critically Ill Patients. Crit Care Med 2013;41: 23732378.10.1097/CCM.0b013e3182923712CrossRefGoogle ScholarPubMed
Stevens, JP, Kachniarz, B, Wright, SB, et al. When policy gets it right: variability in U.S. hospitals’ diagnosis of ventilator-associated pneumonia. Crit Care Med 2014;42: 497503.CrossRefGoogle ScholarPubMed
Klompas, M. Interobserver variability in ventilator-associated pneumonia surveillance. Am J Infect Control 2010;38: 237239.10.1016/j.ajic.2009.10.003CrossRefGoogle ScholarPubMed
Klompas, M, Kulldorff, M, Platt, R. Risk of misleading ventilator-associated pneumonia rates with use of standard clinical and microbiological criteria. Clin Infect Dis 2008;46: 14431446.10.1086/587103CrossRefGoogle ScholarPubMed
Muscedere, JG, Day, A, Heyland, DK. Mortality, attributable mortality, and clinical events as end points for clinical trials of ventilator-associated pneumonia and hospital-acquired pneumonia. Clin Infect Dis 2010;51 Suppl 1: S120125.10.1086/653060CrossRefGoogle ScholarPubMed
van Saene, HK, Silvestri, L, de la Cal, MA, Baines, P. The emperor’s new clothes: the fairy tale continues. J Crit Care 2009;24: 149152.10.1016/j.jcrc.2008.06.015CrossRefGoogle ScholarPubMed
Magill, SS, Fridkin, SK. Improving surveillance definitions for ventilator-associated pneumonia in an era of public reporting and performance measurement. Clin Infect Dis 2012;54: 378380.CrossRefGoogle Scholar
Klompas, M. Eight initiatives that misleadingly lower ventilator-associated pneumonia rates. Am J Infect Control 2012;40: 408410.CrossRefGoogle ScholarPubMed
Klompas, M. Ventilator-associated pneumonia: is zero possible? Clin Infect Dis 2010;51: 11231126.CrossRefGoogle ScholarPubMed
Thomas, BW, Maxwell, RA, Dart, BW, et al. Errors in administrative-reported ventilator-associated pneumonia rates: are never events really so? Am Surg 2011;77: 9981002.CrossRefGoogle Scholar
Skrupsky, LP, McConnell, K, Dallas, J, Kollef, MH. A comparison of ventilator-associated pneumonia rates as identified according to the National Healthcare Safety Network and American College of Chest Physicians criteria. Crit Care Med 2012;40: 281284.10.1097/CCM.0b013e31822d7913CrossRefGoogle Scholar
Novosel, TJ, Hodge, LA, Weireter, LJ, et al. Ventilator-associated pneumonia: depends on your definition. Am Surg 2012;78: 851854.10.1177/000313481207800819CrossRefGoogle ScholarPubMed
Wang, Y, Eldridge, N, Metersky, ML, et al. National trends in patient safety for four common conditions, 2005–2011. N Engl J Med 2014;370: 341351.10.1056/NEJMsa1300991CrossRefGoogle ScholarPubMed
Dudeck, MA, Weiner, LM, Allen-Bridson, K, et al. National Healthcare Safety Network (NHSN) report, data summary for 2012, Device-associated module. Am J Infect Control 2013;41: 11481166.10.1016/j.ajic.2013.09.002CrossRefGoogle ScholarPubMed
Kollef, MH, Chastre, J, Fagon, JY, et al. Global prospective epidemiologic and surveillance study of ventilator-associated pneumonia due to Pseudomonas aeruginosa. Crit Care Med 2014;42: 21782187.CrossRefGoogle ScholarPubMed
Bonten, MJ. Healthcare epidemiology: ventilator-associated pneumonia: preventing the inevitable. Clin Infect Dis 2011;52: 115121.10.1093/cid/ciq075CrossRefGoogle ScholarPubMed
Bouadma, L, Wolff, M, Lucet, JC. Ventilator-associated pneumonia and its prevention. Curr Opin Infect Dis 2012;25: 395404.10.1097/QCO.0b013e328355a835CrossRefGoogle ScholarPubMed
Klompas, M. The paradox of ventilator-associated pneumonia prevention measures. Crit Care 2009;13: 315.10.1186/cc8036CrossRefGoogle ScholarPubMed
Klompas, M, Li, L. Beyond pneumonia: improving care for ventilated patients. Lancet Infect Dis 2013;13: 640641.CrossRefGoogle ScholarPubMed
Klein Klouwenberg, PM, van Mourik, MS, Ong, DS, et al. Electronic implementation of a novel surveillance paradigm for ventilator-associated events: feasibility and validation. Am J Respir Crit Care Med 2014;189: 947955.CrossRefGoogle ScholarPubMed
Lilly, CM, Landry, KE, Sood, RN, et al. Prevalence and Test Characteristics of National Health Safety Network Ventilator-Associated Events. Crit Care Med 2014;42: 20192028.10.1097/CCM.0000000000000396CrossRefGoogle ScholarPubMed
Stevens, JP, Silva, G, Gillis, J, et al. Automated surveillance for ventilator-associated events. Chest 2014;146: 16121618.CrossRefGoogle ScholarPubMed
Magill, S, Gross, C, Edwards, J. Incidence rates of VAE and VAP in the NHSN 2012–2103. IDWeek 2014 Abstract 880; October 8–12, 2014.Google Scholar
Klompas, M, Kleinman, K, Murphy, MV. Descriptive epidemiology and attributable morbidity of ventilator-associated events. Infect Control Hosp Epidemiol 2014;35: 502510.10.1086/675834CrossRefGoogle ScholarPubMed
Klompas, M, Khan, Y, Kleinman, K, et al. Multicenter Evaluation of a Novel Surveillance Paradigm for Complications of Mechanical Ventilation. PLoS ONE 2011;6: e18062.CrossRefGoogle ScholarPubMed
Klompas, M, Magill, S, Robicsek, A, et al. Objective surveillance definitions for ventilator-associated pneumonia. Crit Care Med 2012;40: 31543161.10.1097/CCM.0b013e318260c6d9CrossRefGoogle ScholarPubMed
Muscedere, J, Sinuff, T, Heyland, D, et al. The clinical impact and preventability of ventilator-associated conditions in critically ill mechanically ventilated patients. Chest 2013;144: 14531460.10.1378/chest.13-0853CrossRefGoogle Scholar
Bouadma, L, Sonneville, R, Garrouste-Orgeas, M, et al. Ventilator-associated events: prevalence, outcome, and relationship with ventilator-associated pneumonia. Crit Care Med 2015;43: 17981806.CrossRefGoogle ScholarPubMed
Hayashi, Y, Morisawa, K, Klompas, M, et al. Toward improved surveillance: the impact of ventilator-associated complications on length of stay and antibiotic use in patients in intensive care units. Clin Infect Dis 2013;56: 471477.CrossRefGoogle ScholarPubMed
Nuckchady, D, Heckman, MG, Diehl, NN, et al. Assessment of an automated surveillance system for detection of initial ventilator-associated events. Am J Infect Control 2015;43: 11191121.10.1016/j.ajic.2015.05.040CrossRefGoogle ScholarPubMed
Mann, T, Ellsworth, J, Huda, N, et al. Building and validating a computerized algorithm for surveillance of ventilator-associated events. Infect Control Hosp Epidemiol 2015: 15.Google ScholarPubMed
Magill, SS, Rhodes, B, Klompas, M. Improving ventilator-associated event surveillance in the National Healthcare Safety Network and addressing knowledge gaps: update and review. Curr Opin Infect Dis 2014;27: 394400.10.1097/QCO.0000000000000083CrossRefGoogle ScholarPubMed
Phongjitsiri, S, Coss-Bu, J, Kennedy, C, et al. The Centers for Disease Control and Prevention’s new definitions for complications of mechanical ventilation shift the focus of quality surveillance and predict clinical outcomes in a PICU. Crit Care Med 2015;43: 24462451.CrossRefGoogle ScholarPubMed
Cocoros, NM, Kleinman, K, Priebe, GP, et al. Ventilator-associated events in neonates and children: a new paradigm. Crit Care Med 2016;44: 1422.10.1097/CCM.0000000000001372CrossRefGoogle ScholarPubMed
Herzig, SJ, Howell, MD, Ngo, LH, Marcantonio, ER. Acid-suppressive medication use and the risk for hospital-acquired pneumonia. JAMA 2009;301: 21202128.CrossRefGoogle ScholarPubMed
Klompas, M, Speck, K, Howell, MD, Greene, LR, Berenholtz, SM. Reappraisal of routine oral care with chlorhexidine gluconate for patients receiving mechanical ventilation: systematic review and meta-analysis. JAMA internal medicine 2014;174: 751761.CrossRefGoogle ScholarPubMed
Price, R, MacLennan, G, Glen, J. Selective digestive or oropharyngeal decontamination and topical oropharyngeal chlorhexidine for prevention of death in general intensive care: systematic review and network meta-analysis. BMJ 2014;348: g2197.10.1136/bmj.g2197CrossRefGoogle ScholarPubMed
Caroff, DA, Li, L, Muscedere, J, Klompas, M. Subglottic secretion drainage and objective outcomes: a systematic review and meta-analysis. Crit Care Med 2015.Google Scholar
Klompas, M, Branson, R, Eichenwald, EC, et al. Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol 2014;35: 915936.CrossRefGoogle ScholarPubMed
Klompas, M. Potential strategies to prevent ventilator-associated events. Am J Respir Crit Care Med 2015;192: 14201430.10.1164/rccm.201506-1161CICrossRefGoogle ScholarPubMed
Girard, TD, Kress, JP, Fuchs, BD, et al. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet 2008;371: 126134.10.1016/S0140-6736(08)60105-1CrossRefGoogle Scholar
Schweickert, WD, Pohlman, MC, Pohlman, AS, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 2009;373:18741882.10.1016/S0140-6736(09)60658-9CrossRefGoogle ScholarPubMed
Determann, RM, Royakkers, A, Wolthuis, EK, et al. Ventilation with lower tidal volumes as compared with conventional tidal volumes for patients without acute lung injury: a preventive randomized controlled trial. Crit Care 2010;14: R1.10.1186/cc8230CrossRefGoogle ScholarPubMed
Gajic, O, Rana, R, Mendez, JL, et al. Acute lung injury after blood transfusion in mechanically ventilated patients. Transfusion (Paris) 2004;44: 14681474.10.1111/j.1537-2995.2004.04053.xCrossRefGoogle ScholarPubMed
Mekontso Dessap, A, Roche-Campo, F, Kouatchet, A, et al. Natriuretic peptide-driven fluid management during ventilator weaning: a randomized controlled trial. Am J Respir Crit Care Med 2012;186: 12561263.10.1164/rccm.201205-0939OCCrossRefGoogle ScholarPubMed
Lewis, SC, Li, L, Murphy, MV, Klompas, M. Risk factors for ventilator-associated events: a case-control multivariable analysis. Crit Care Med 2014;42: 18391848.10.1097/CCM.0000000000000338CrossRefGoogle ScholarPubMed
Klompas, M, Anderson, D, Trick, W, et al. The preventability of ventilator-associated events: The CDC Prevention Epicenters Wake Up and Breathe Collaborative. Am J Respir Crit Care Med 2015;191: 292301.10.1164/rccm.201407-1394OCCrossRefGoogle ScholarPubMed
Sinuff, T, Muscedere, J, Cook, DJ, et al. Implementation of clinical practice guidelines for ventilator-associated pneumonia: a multicenter prospective study. Crit Care Med 2013;41: 1523.CrossRefGoogle ScholarPubMed
Mekontso Dessap, A, Katsahian, S, Roche-Campo, F, et al. Ventilator-associated pneumonia during weaning from mechanical ventilation: role of fluid management. Chest 2014:ePub ahead of print.Google ScholarPubMed
Damas, P, Frippiat, F, Ancion, A, et al. Prevention of ventilator-associated pneumonia and ventilator-associated conditions: a randomized controlled trial with subglottic secretion suctioning. Crit Care Med 2015;43: 2230.10.1097/CCM.0000000000000674CrossRefGoogle ScholarPubMed
Klompas, M. Ventilator-associated conditions versus ventilator-associated pneumonia: different by design. Curr Infect Dis Rep 2014;16: 430.10.1007/s11908-014-0430-0CrossRefGoogle ScholarPubMed

References

Lewis, SS, Moehring, RW, Chen, LF, Sexton, DJ, Anderson, DJ. Assessing the relative burden of hospital-acquired infections in a network of community hospitals. Infect Control Hosp Epidemiol 2013;34: 12291230.CrossRefGoogle Scholar
Burke, JP. Infection control: a problem for patient safety. N Engl J Med 2003;348: 651656.CrossRefGoogle ScholarPubMed
Zimlichman, E, Henderson, D, Tamir, O, et al. Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system. JAMA Intern Med 2013;173: 20392046.10.1001/jamainternmed.2013.9763CrossRefGoogle ScholarPubMed
Martone, WJ, Nichols, RL. Recognition, prevention, surveillance, and management of surgical site infections: introduction to the problem and symposium overview. Clin Infect Dis 2001;33 Suppl 2:S67S68.10.1086/321859CrossRefGoogle Scholar
Scott, RD II. The Direct Medical Costs of Healthcare-Associated Infections in U.S. Hospitals and the Benefits of Prevention. In: Economist Division of Healthcare Quality Promotion National Center for Preparedness D, and Control of Infectious Diseases; Coordinating Center for Infectious Diseases Centers for Disease Control and Prevention, ed. 2009: 13.Google Scholar
Engemann, JJ, Carmeli, Y, Cosgrove, SE, et al. Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection. Clin Infect Dis 2003;36: 592598.10.1086/367653CrossRefGoogle ScholarPubMed
Kirkland, KB, Briggs, JP, Trivette, SL, Wilkinson, WE, Sexton, DJ. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 1999;20: 725730.10.1086/501572CrossRefGoogle ScholarPubMed
McGarry, SA, Engemann, JJ, Schmader, K, Sexton, DJ, Kaye, KS. Surgical-site infection due to Staphylococcus aureus among elderly patients: Mortality, duration of hospitalization, and cost. Infect Cont Hosp Ep 2004;25: 461467.CrossRefGoogle ScholarPubMed
Haley, RW, Culver, DH, White, JW, et al. The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals. Am J Epidemiol 1985;121: 182205.CrossRefGoogle ScholarPubMed
Cruse, PJ, Foord, R. The epidemiology of wound infection: a 10-year prospective study of 62,939 wounds. Surg Clin North Am 1980;60: 2740.10.1016/S0039-6109(16)42031-1CrossRefGoogle Scholar
Olson, MM, Lee, JT Jr. Continuous, 10-year wound infection surveillance: results, advantages, and unanswered questions. Arch Surg 1990;125: 794803.10.1001/archsurg.1990.01410180120020CrossRefGoogle ScholarPubMed
Horan, TC, Gaynes, RP, Martone, WJ, Jarvis, WR, Emori, TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 1992;13: 606608.CrossRefGoogle ScholarPubMed
Ehrenkranz, NJ, Richter, EI, Phillips, PM, Shultz, JM. An apparent excess of operative site infections: analyses to evaluate false-positive diagnoses. Infect Control Hosp Epidemiol 1995;16: 712716.10.1086/647045CrossRefGoogle ScholarPubMed
Ehrenkranz, NJ, Richter, EI, Phillips, PM, Shultz, JM. An apparent excess of operative site infections: analyses to evaluate false-positive diagnoses. Infect Control Hops Epidemiol 1995;16: 712–6.Google ScholarPubMed
Lee, JT. Wound infection surveillance. Infect Dis Clin North Am 1992;6: 643656.CrossRefGoogle ScholarPubMed
Haley, RW, Schaberg, DR, McClish, DK, et al. The accuracy of retrospective chart review in measuring nosocomial infection rates: results of validation studies in pilot hospitals. Am J Epidemiol 1980;111: 516533.10.1093/oxfordjournals.aje.a112931CrossRefGoogle ScholarPubMed
Cardo, DM, Falk, PS, Mayhall, CG. Validation of surgical wound surveillance. Infect Control Hosp Epidemiol 1993;14: 211215.10.1086/646717CrossRefGoogle ScholarPubMed
Berard, F, Gandon, J. Postoperative wound infections: the influence of ultraviolet irradiation of the operating room and of various other factors. Ann Surg 1964;160(Suppl 2): 192.Google ScholarPubMed
Haley, RW. Surveillance by objective: a new priority-directed approach to the control of nosocomial infections: The National Foundation for Infectious Diseases lecture. Am J Infect Control 1985;13: 7889.10.1016/0196-6553(85)90085-9CrossRefGoogle Scholar
Sands, K, Vineyard, G, Platt, R. Surgical site infections occurring after hospital discharge. J Infect Dis 1996;173: 963970.10.1093/infdis/173.4.963CrossRefGoogle ScholarPubMed
Anderson, DJ, Arduino, JM, Reed, SD, et al. Variation in the type and frequency of postoperative invasive Staphylococcus aureus infections according to type of surgical procedure. Infect Control Hosp Epidemiol 2010;31: 701709.10.1086/653205CrossRefGoogle ScholarPubMed
Ferraz, EM, Bacelar, TS, Aguiar, JL, Ferraz, AA, Pagnossin, G, Batista, JE. Wound infection rates in clean surgery: a potentially misleading risk classification. Infect Control Hosp Epidemiol 1992;13: 457462.CrossRefGoogle ScholarPubMed
Haley, RW, Culver, DH, Morgan, WM, White, JW, Emori, TG, Hooton, TM. Identifying patients at high-risk of surgical wound-infection: a simple multivariate index of patient susceptibility and wound contamination. Am J Epidemiol 1985;121: 206215.10.1093/oxfordjournals.aje.a113991CrossRefGoogle ScholarPubMed
Culver, DH, Horan, TC, Gaynes, RP, et al. Surgical wound infection rates by wound class, operative procedure, and patient risk index: National Nosocomial Infections Surveillance System. Am J Med 1991;91: 152S157S.CrossRefGoogle ScholarPubMed
Roy, MC, Herwaldt, LA, Embrey, R, Kuhns, K, Wenzel, RP, Perl, TM. Does the Centers for Disease Control’s NNIS System risk index stratify patients undergoing cardiothoracic operations by their risk of surgical-site infection? Infect Cont Hosp Ep 2000;21: 186190.10.1086/501741CrossRefGoogle ScholarPubMed
Nichols, RL, Smith, JW, Robertson, GD, et al. Prospective alterations in therapy for penetrating abdominal trauma. Arch Surg 1993;128: 5563; discussion -4.10.1001/archsurg.1993.01420130059010CrossRefGoogle ScholarPubMed
Wenzel, RP, Osterman, CA, Hunting, KJ, Gwaltney, JM Jr. Hospital-acquired infections: I. Surveillance in a university hospital. Am J Epidemiol 1976;103: 251260.10.1093/oxfordjournals.aje.a112223CrossRefGoogle ScholarPubMed
Yokoe, DS, Noskin, GA, Cunningham, SM, et al. Enhanced identification of postoperative infections among inpatients. Emerg Infect Dis 2004;10: 19241230.10.3201/eid1011.040572CrossRefGoogle ScholarPubMed
Platt, R, Yokoe, DS, Sands, KE. Automated methods for surveillance of surgical site infections. Emerg Infect Dis 2001;7: 212216.10.3201/eid0702.010212CrossRefGoogle ScholarPubMed
Perl, TM. Surveillance, Reporting and the Use of Computers. 2nd ed. Williams & Wilkins; 1993.Google Scholar
Huang, SS, Placzek, H, Livingston, J, et al. Use of Medicare claims to rank hospitals by surgical site infection risk following coronary artery bypass graft surgery. Infect Cont Hosp Ep 2011;32: 775783.10.1086/660874CrossRefGoogle ScholarPubMed
Calderwood, MS, Kleinman, K, Bratzler, DW, et al. Use of Medicare claims to identify us hospitals with a high rate of surgical site infection after hip arthroplasty. Infect Cont Hosp Ep 2013;34: 3139.10.1086/668785CrossRefGoogle ScholarPubMed
Manian, FA, Meyer, L. Comprehensive surveillance of surgical wound infections in outpatient and inpatient surgery. Infect Control Hosp Epidemiol 1990;11: 515520.10.1086/646084CrossRefGoogle ScholarPubMed
Avato, JL, Lai, KK. Impact of postdischarge surveillance on surgical-site infection rates for coronary artery bypass procedures. Infect Control Hosp Epidemiol 2002;23: 364367.10.1086/502076CrossRefGoogle ScholarPubMed
Delgado-Rodriguez, M, Gomez-Ortega, A, Sillero-Arenas, M, Llorca, J. Epidemiology of surgical-site infections diagnosed after hospital discharge: a prospective cohort study. Infect Control Hosp Epidemiol 2001;22: 2430.10.1086/501820CrossRefGoogle ScholarPubMed
Ming, DY, Chen, LF, Miller, BA, Anderson, DJ. The impact of depth of infection and postdischarge surveillance on rate of surgical-site infections in a network of community hospitals. Infect Control Hosp Epidemiol 2012;33: 276282.10.1086/664053CrossRefGoogle Scholar
Perencevich, EN, Sands, KE, Cosgrove, SE, Guadagnoli, E, Meara, E, Platt, R. Health and economic impact of surgical site infections diagnosed after hospital discharge. Emerg Infect Dis 2003;9: 196203.10.3201/eid0902.020232CrossRefGoogle ScholarPubMed
Noy, D, Creedy, D. Postdischarge surveillance of surgical site infections: a multi-method approach to data collection. Am J Infect Control 2002;30: 417424.10.1067/mic.2002.123393CrossRefGoogle ScholarPubMed
Kent, P, McDonald, M, Harris, O, Mason, T, Spelman, D. Post-discharge surgical wound infection surveillance in a provincial hospital: follow-up rates, validity of data and review of the literature. ANZ J Surg 2001;71: 583589.10.1046/j.1445-2197.2001.02215.xCrossRefGoogle Scholar
Burns, SJ, Dippe, SE. Postoperative wound infections detected during hospitalization and after discharge in a community hospital. Am J Infect Control 1982;10: 6065.10.1016/0196-6553(82)90004-9CrossRefGoogle Scholar
Seaman, M, Lammers, R. Inability of patients to self-diagnose wound infections. J Emerg Med 1991;9: 215219.10.1016/0736-4679(91)90416-DCrossRefGoogle ScholarPubMed
Anderson, DJ, Kaye, KS, Classen, D, et al. Strategies to prevent surgical site infections in acute care hospitals. Infect Control Hosp Epidemiol 2008;29 Suppl 1:S51S61.10.1086/591064CrossRefGoogle ScholarPubMed
Sands, K, Vineyard, G, Livingston, J, Christiansen, C, Platt, R. Efficient identification of postdischarge surgical site infections: use of automated pharmacy dispensing information, administrative data, and medical record information. J Infect Dis 1999;179: 434441.10.1086/314586CrossRefGoogle ScholarPubMed
Chalfine, A, Cauet, D, Lin, WC, et al. Highly sensitive and efficient computer-assisted system for routine surveillance for surgical site infection. Infect Control Hosp Epidemiol 2006;27: 794801.10.1086/506393CrossRefGoogle ScholarPubMed
Platt, R, Kleinman, K, Thompson, K, et al. Using automated health plan data to assess infection risk from coronary artery bypass surgery. Emerg Infect Dis 2002;8: 14331441.10.3201/eid0812.020039CrossRefGoogle ScholarPubMed
Hirschhorn, LR, Currier, JS, Platt, R. Electronic surveillance of antibiotic exposure and coded discharge diagnoses as indicators of postoperative infection and other quality assurance measures. Infect Control Hosp Epidemiol 1993;14: 2128.10.1086/646626CrossRefGoogle ScholarPubMed
Bouam, S, Girou, E, Brun-Buisson, C, Karadimas, H, Lepage, E. An intranet-based automated system for the surveillance of nosocomial infections: prospective validation compared with physicians’ self-reports. Infect Control Hosp Epidemiol 2003;24: 5155.10.1086/502115CrossRefGoogle ScholarPubMed
Burke, JP. Surveillance, reporting, automation, and interventional epidemiology. Infect Control Hosp Epidemiol 2003;24: 1012.10.1086/502108CrossRefGoogle ScholarPubMed
Mayhall, CG. Surgical Infections Including Burns. Baltimore, MD: Williams & Wilkins; 1993.Google Scholar
DS K, AB K. Postoperative Infections and Antimicrobial Prophylaxis. 4th ed. New York, NY: Chirchill Livingstone; 1995.Google Scholar
Nagachinta, T, Stephens, M, Reitz, B, Polk, BF. Risk factors for surgical-wound infection following cardiac surgery. J Infect Dis 1987;156: 967973.10.1093/infdis/156.6.967CrossRefGoogle ScholarPubMed
Weintraub, WS, Jones, EL, Craver, J, Guyton, R, Cohen, C. Determinants of prolonged length of hospital stay after coronary bypass surgery. Circulation 1989;80: 276284.10.1161/01.CIR.80.2.276CrossRefGoogle ScholarPubMed
Taylor, GJ, Mikell, FL, Moses, HW, et al. Determinants of hospital charges for coronary artery bypass surgery: the economic consequences of postoperative complications. Am J Cardiol 1990;65: 309313.10.1016/0002-9149(90)90293-ACrossRefGoogle ScholarPubMed
Mangram, AJ, Horan, TC, Pearson, ML, Silver, LC, Jarvis, WR. Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control 1999;27: 97132; quiz 3–4; discussion 96.10.1016/S0196-6553(99)70088-XCrossRefGoogle ScholarPubMed
Bratzler, DW, Hunt, DR. The surgical infection prevention and surgical care improvement projects: national initiatives to improve outcomes for patients having surgery. Clin Infect Dis 2006;43: 322330.10.1086/505220CrossRefGoogle ScholarPubMed
Bratzler, DW, Houck, PM, Richards, C, et al. Use of antimicrobial prophylaxis for major surgery: baseline results from The National Surgical Infection Prevention Project. Arch Surg-Chicago 2005;140: 174182.10.1001/archsurg.140.2.174CrossRefGoogle ScholarPubMed
Dellinger, EP, Hausmann, SM, Bratzler, DW, et al. Hospitals collaborate to decrease surgical site infections. Am J Surg 2005;190: 915.10.1016/j.amjsurg.2004.12.001CrossRefGoogle ScholarPubMed
Haynes, AB, Weiser, TG, Berry, WR, et al. A surgical safety checklist to reduce morbidity and mortality in a global population. N Engl J Med 2009;360: 491499.CrossRefGoogle Scholar
Weiser, TG, Haynes, AB, Dziekan, G, et al. Effect of a 19-item surgical safety checklist during urgent operations in a global patient population. Ann Surg 2010;251: 976980.10.1097/SLA.0b013e3181d970e3CrossRefGoogle Scholar
van Klei, WA, Hoff, RG, van Aarnhem, EEHL, et al. Effects of the introduction of the WHO “Surgical Safety Checklist” on in-hospital mortality: a cohort study. Ann Surg 2012;255: 4449.CrossRefGoogle ScholarPubMed
Institute for Healthcare Improvement. 2009. Available at: www.ihi.org. Accessed April 22, 2009.Google Scholar
Yokoe, DS, Mermel, LA, Anderson, DJ, et al. A compendium of strategies to prevent healthcare-associated infections in acute care hospitals. Infect Control Hosp Epidemiol 2008;29 Suppl 1:S12S21.10.1086/591060CrossRefGoogle ScholarPubMed
Yokoe, DS, Classen, D. Improving patient safety through infection control: a new healthcare imperative. Infect Cont Hosp Ep 2008;29:S3S11.10.1086/591063CrossRefGoogle ScholarPubMed
Anderson, DJ, Podgorny, K, Berrios-Torres, SI, et al. Strategies to prevent surgical site infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol 2014;35: 605627.10.1086/676022CrossRefGoogle ScholarPubMed
Schweizer, ML, Chiang, HY, Septimus, E, et al. Association of a bundled intervention with surgical site infections among patients undergoing cardiac, hip, or knee surgery. JAMA 2015;313: 21622171.10.1001/jama.2015.5387CrossRefGoogle ScholarPubMed
Perl, TM, Golub, JE. New approaches to reduce Staphylococcus aureus nosocomial infection rates: treating S. aureus nasal carriage. Ann Pharmacother 1998;32:S7S16.10.1177/106002809803200104CrossRefGoogle ScholarPubMed
Wenzel, RP, Perl, TM. The significance of nasal carriage of Staphylococcus aureus and the incidence of postoperative wound infection. J Hosp Infect 1995;31: 1324.10.1016/0195-6701(95)90079-9CrossRefGoogle ScholarPubMed
Kluytmans, J, van Belkum, A, Verbrugh, H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev 1997;10: 505520.10.1128/CMR.10.3.505CrossRefGoogle ScholarPubMed
Perl, TM, Cullen, JJ, Wenzel, RP, et al. Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections. N Engl J Med 2002;346: 18711877.CrossRefGoogle ScholarPubMed
Bode, LG, Kluytmans, JA, Wertheim, HF, et al. Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N Engl J Med 2010;362: 917.10.1056/NEJMoa0808939CrossRefGoogle ScholarPubMed
Schweizer, M, Perencevich, E, McDanel, J, et al. Effectiveness of a bundled intervention of decolonization and prophylaxis to decrease Gram positive surgical site infections after cardiac or orthopedic surgery: systematic review and meta-analysis. BMJ 2013;346: f2743.CrossRefGoogle ScholarPubMed
van Rijen, M, Bonten, M, Wenzel, R, Kluytmans, J. Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers. Cochrane Database Syst Rev 2008: CD006216.Google ScholarPubMed
Surgical Attire. Association of periOperative Registered Nurses. Available at www.aorn.org/guidelines/clinical-resources/clinical-faqs/attire. Accessed March 28, 2016.Google Scholar
Bratzler, DW, Dellinger, EP, Olsen, KM, et al. Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery. Surg Infect 2013;14: 73156.10.1089/sur.2013.9999CrossRefGoogle ScholarPubMed
Zanetti, G, Flanagan, HL Jr., Cohn, LH, Giardina, R, Platt, R. Improvement of intraoperative antibiotic prophylaxis in prolonged cardiac surgery by automated alerts in the operating room. Infect Control Hosp Epidemiol 2003;24: 1316.10.1086/502109CrossRefGoogle ScholarPubMed
Webb, ALB, Flagg, RL, Fink, AS. Reducing surgical site infections through a multidisciplinary computerized process for preoperative prophylactic antibiotic administration. Am. J. Surg. 2006;192: 663668.10.1016/j.amjsurg.2006.08.014CrossRefGoogle ScholarPubMed
Kanter, G, Connelly, NR, Fitzgerald, J. A system and process redesign to improve perioperative antibiotic administration. Anesth Analg 2006;103: 15171521.10.1213/01.ane.0000221442.30952.83CrossRefGoogle ScholarPubMed
Steinberg, JP, Braun, BI, Hellinger, WC, et al. Timing of antimicrobial prophylaxis and the risk of surgical site infections: results from the Trial to Reduce Antimicrobial Prophylaxis Errors. Ann Surg 2009;250: 1016.10.1097/SLA.0b013e3181ad5fcaCrossRefGoogle ScholarPubMed
van Kasteren, MEE, Mannien, J, Ott, A, Kullberg, BJ, de Boer, AS, Gyssens, IC. Antibiotic prophylaxis and the risk of surgical site infections following total hip arthroplasty: timely administration is the most important factor. Clin Infect Dis 2007;44: 921927.10.1086/512192CrossRefGoogle ScholarPubMed
Soriano, A, Marco, F, Martinez, JA, et al. Influence of vancomycin minimum inhibitory concentration on the treatment of methicillin-resistant Staphylococcus aureus bacteremia. Clin Infect Dis 2008;46: 193200.10.1086/524667CrossRefGoogle ScholarPubMed
Akinyoola, AL, Adegbehingbe, OO, Odunsi, A. Timing of antibiotic prophylaxis in tourniquet surgery. J Foot Ankle Surg 2011;50: 374376.10.1053/j.jfas.2011.04.008CrossRefGoogle ScholarPubMed
Andersson, AE, Bergh, I, Karlsson, J, Eriksson, BI, Nilsson, K. Traffic flow in the operating room: an explorative and descriptive study on air quality during orthopedic trauma implant surgery. Am J Infect Control 2012;40: 750755.10.1016/j.ajic.2011.09.015CrossRefGoogle Scholar
Pada, S, Perl, TM. Operating room myths: what is the evidence for common practices. Curr Opin Infect Dis 2015;28: 369374.10.1097/QCO.0000000000000177CrossRefGoogle Scholar
van der Slegt, J, van der Laan, L, Veen, EJ, Hendriks, Y, Romme, J, Kluytmans, J. Implementation of a bundle of care to reduce surgical site infections in patients undergoing vascular surgery. PLoS One 2013;8: e71566.10.1371/journal.pone.0071566CrossRefGoogle ScholarPubMed
Darouiche, RO, Wall, MJ Jr., Itani, KM, et al. Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis. N Engl J Med 2010;362: 1826.10.1056/NEJMoa0810988CrossRefGoogle ScholarPubMed
Swenson, BR, Hedrick, TL, Metzger, R, Bonatti, H, Pruett, TL, Sawyer, RG. Effects of preoperative skin preparation on postoperative wound infection rates: a prospective study of 3 skin preparation protocols. Infect Control Hosp Epidemiol 2009;30: 964971.10.1086/605926CrossRefGoogle Scholar
Kurz, A, Sessler, DI, Lenhardt, R. Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization: study of wound infection and temperature group. N Engl J Med 1996;334: 12091215.10.1056/NEJM199605093341901CrossRefGoogle ScholarPubMed
Sessler, DI, Akca, O. Nonpharmacological prevention of surgical wound infections. Clin Infect Dis 2002;35: 13971404.10.1086/344275CrossRefGoogle ScholarPubMed
Melling, AC, Ali, B, Scott, EM, Leaper, DJ. Effects of preoperative warming on the incidence of wound infection after clean surgery: a randomised controlled trial. Lancet 2001;358: 876880.10.1016/S0140-6736(01)06071-8CrossRefGoogle ScholarPubMed
Latham, R, Lancaster, AD, Covington, JF, Pirolo, JS, Thomas, CS. The association of diabetes and glucose control with surgical-site infections among cardiothoracic surgery patients. Infect Cont Hosp Ep 2001;22: 607612.10.1086/501830CrossRefGoogle ScholarPubMed
Dellinger, EP. Preventing surgical-site infections: the importance of timing and glucose control. Infect Control Hosp Epidemiol 2001;22: 604606.10.1086/501829CrossRefGoogle ScholarPubMed
van den Berghe, G, Wouters, P, Weekers, F, et al. Intensive insulin therapy in critically ill patients. N Engl J Med 2001;345: 13591367.10.1056/NEJMoa011300CrossRefGoogle ScholarPubMed
Kwon, S, Thompson, R, Dellinger, P, Yanez, D, Farrohki, E, Flum, D. Importance of perioperative glycemic control in general surgery: a report from the Surgical Care and Outcomes Assessment Program. Ann Surg 2013;257: 814.10.1097/SLA.0b013e31827b6bbcCrossRefGoogle ScholarPubMed
Umpierrez, GE, Smiley, D, Jacobs, S, et al. Randomized study of basal-bolus insulin therapy in the inpatient management of patients with type 2 diabetes undergoing general surgery (RABBIT 2 surgery). Diabetes Care 2011;34: 256261.10.2337/dc10-1407CrossRefGoogle ScholarPubMed
Hopf, HW, Hunt, TK, West, JM, et al. Wound tissue oxygen tension predicts the risk of wound infection in surgical patients. Arch Surg 1997;132: 9971004; discussion 5.CrossRefGoogle ScholarPubMed
Greif, R, Akca, O, Horn, EP, Kurz, A, Sessler, DI, Grp, OR. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med 2000;342: 161–167.CrossRefGoogle ScholarPubMed
Bickel, A, Gurevits, M, Vamos, R, Ivry, S, Eitan, A. Perioperative hyperoxygenation and wound site infection following surgery for acute appendicitis: a randomized, prospective, controlled trial. Arch Surg 2011;146: 464470.10.1001/archsurg.2011.65CrossRefGoogle ScholarPubMed
Rohde, JM, Dimcheff, DE, Blumberg, N, et al. Health care–associated infection after red blood cell transfusion: a systematic review and meta-analysis. JAMA 2014;311: 13171326.10.1001/jama.2014.2726CrossRefGoogle ScholarPubMed

References

Climo, M, Diekema, D, Warren, DK, et al. Prevalence of the use of central venous access devices within and outside of the intensive care unit: results of a survey among hospitals in the prevention epicenter program of the Centers for Disease Control and Prevention. Infect Control Hosp Epidemiol. 2003;24(12):942945.10.1086/502163CrossRefGoogle ScholarPubMed
Pronovost, P, Needham, D, Berenholtz, S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med. 2006;355(26):27252732.10.1056/NEJMoa061115CrossRefGoogle ScholarPubMed
Raad, I, Hanna, H, Maki, D. Intravascular catheter-related infections: advances in diagnosis, prevention, and management. Lancet infectious diseases. 2007;7(10):645657.10.1016/S1473-3099(07)70235-9CrossRefGoogle ScholarPubMed
Pittet, D, Tarara, D, Wenzel, RP. Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra costs, and attributable mortality. JAMA. 1994;271(20):15981601.10.1001/jama.1994.03510440058033CrossRefGoogle ScholarPubMed
Soufir, L, Timsit, JF, Mahe, C, Carlet, J, Regnier, B, Chevret, S. Attributable morbidity and mortality of catheter-related septicemia in critically ill patients: a matched, risk-adjusted, cohort study. Infect Control Hosp Epidemiol. 1999;20(6):396401.10.1086/501639CrossRefGoogle ScholarPubMed
Digiovine, B, Chenoweth, C, Watts, C, Higgins, M. The attributable mortality and costs of primary nosocomial bloodstream infections in the intensive care unit. Am J Respir Crit Care Med. 1999;160(3):976981.10.1164/ajrccm.160.3.9808145CrossRefGoogle ScholarPubMed
Rello, J, Ochagavia, A, Sabanes, E, et al. Evaluation of outcome of intravenous catheter-related infections in critically ill patients. Am J Respir Crit Care Med. 2000;162(3 Pt 1):10271030.10.1164/ajrccm.162.3.9911093CrossRefGoogle ScholarPubMed
Pelletier, SJ, Crabtree, TD, Gleason, TG, Pruett, TL, Sawyer, RG. Bacteremia associated with central venous catheter infection is not an independent predictor of outcomes. J Am Coll Surg. 2000;190(6):671680; discussion 80–81.10.1016/S1072-7515(00)00266-0CrossRefGoogle Scholar
Renaud, B, Brun-Buisson, C. Outcomes of primary and catheter-related bacteremia: a cohort and case-control study in critically ill patients. Am J Respir Crit Care Med. 2001;163(7):15841590.10.1164/ajrccm.163.7.9912080CrossRefGoogle ScholarPubMed
Rosenthal, VD, Guzman, S, Migone, O, Crnich, CJ. The attributable cost, length of hospital stay, and mortality of central line–associated bloodstream infection in intensive care departments in Argentina: a prospective, matched analysis. Am J Infect Control. 2003;31(8):475480.10.1016/j.ajic.2003.03.002CrossRefGoogle ScholarPubMed
Blot, SI, Depuydt, P, Annemans, L, et al. Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections. Clin Infect Dis. 2005;41(11):15911508.10.1086/497833CrossRefGoogle ScholarPubMed
Stevens, V, Geiger, K, Concannon, C, Nelson, RE, Brown, J, Dumyati, G. Inpatient costs, mortality and 30-day re-admission in patients with central-line-associated bloodstream infections. Clin Microbiol Infect. 2014;20(5):O3180324.10.1111/1469-0691.12407CrossRefGoogle ScholarPubMed
Goudie, A, Dynan, L, Brady, PW, Rettiganti, M. Attributable cost and length of stay for central line-associated bloodstream infections. Pediatrics. 2014;133(6):e15251532.10.1542/peds.2013-3795CrossRefGoogle ScholarPubMed
Zingg, W, Cartier-Fassler, V, Walder, B. Central venous catheter-associated infections. Best Pract Res Clin Anaesthesiol. 2008;22(3):407421.10.1016/j.bpa.2008.05.007CrossRefGoogle ScholarPubMed
Vincent, JL, Bihari, DJ, Suter, PM, et al. The prevalence of nosocomial infection in intensive care units in Europe: results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA. 1995;274(8):639644.CrossRefGoogle Scholar
Vincent, JL, Rello, J, Marshall, J, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA. 2009;302(21):23232329.10.1001/jama.2009.1754CrossRefGoogle Scholar
Dudeck, MA, Edwards, JR, Allen-Bridson, K, et al. National Healthcare Safety Network report, data summary for 2013: device-associated Module. Am J Infect Control. 2015;43(3):206221.10.1016/j.ajic.2014.11.014CrossRefGoogle ScholarPubMed
Coello, R, Charlett, A, Ward, V, et al. Device-related sources of bacteraemia in English hospitals: opportunities for the prevention of hospital-acquired bacteraemia. J Hosp Infect. 2003;53(1):4657.10.1053/jhin.2002.1349CrossRefGoogle ScholarPubMed
Rosenthal, VD, Maki, DG, Salomao, R, et al. Device-associated nosocomial infections in 55 intensive care units of 8 developing countries. Ann Intern Med. 2006;145(8):582591.10.7326/0003-4819-145-8-200610170-00007CrossRefGoogle ScholarPubMed
Rosenthal, VD, Maki, DG, Mehta, Y, et al. International Nosocomial Infection Control Consortium (INICC) report, data summary of 43 countries for 2007–2012: device-associated module. Am J Infect Control. 2014;42(9):942–56.10.1016/j.ajic.2014.05.029CrossRefGoogle ScholarPubMed
Mostert, JW, Kenny, GM, Murphy, GP. Safe placement of central venous catheter into internal jugular veins. Arch Surg. 1970;101(3):431432.10.1001/archsurg.1970.01340270079021CrossRefGoogle ScholarPubMed
Peters, JL, Mehtar, S, Vallis, CJ, Kenning, BR. Central venous catheter design and maintenance complications. Br J Anaesth. 1979;51(8):805806.10.1093/bja/51.8.805-cCrossRefGoogle ScholarPubMed
Pottecher, T, Forrler, M, Picardat, P, Krause, D, Bellocq, JP, Otteni, JC. Thrombogenicity of central venous catheters: prospective study of polyethylene, silicone and polyurethane catheters with phlebography or post-mortem examination. Eur Journal Anaesthesiol. 1984;1(4):361365.Google ScholarPubMed
Haley, RW, Quade, D, Freeman, HE, Bennett, JV. The SENIC Project: Study on the efficacy of nosocomial infection control (SENIC Project), Summary of study design. Am J Epidemiol. 1980;111(5):472–85.10.1093/oxfordjournals.aje.a112928CrossRefGoogle Scholar
O’Grady, NP, Alexander, M, Dellinger, EP, et al. Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR Recommendations and Reports. 2002;51(RR-10):129.Google ScholarPubMed
Marschall, J, Mermel, LA, Fakih, M, et al. Strategies to prevent central line–associated bloodstream infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014;35 Suppl 2:S89S107.10.1086/676533CrossRefGoogle ScholarPubMed
Maki, DG, Kluger, DM, Crnich, CJ. The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clinic Pro. 2006;81(9):115911571.10.4065/81.9.1159CrossRefGoogle ScholarPubMed
Al Raiy, B, Fakih, MG, Bryan-Nomides, N et al. Peripherally inserted central venous catheters in the acute care setting: a safe alternative to high-risk short-term central venous catheters. Am J Infect Control. 2010;38(2):149153.10.1016/j.ajic.2009.06.008CrossRefGoogle ScholarPubMed
Zingg, W, Pittet, D. Peripheral venous catheters: an under-evaluated problem. Int J Antimicrob Agents. 2009;34 Suppl 4:S38S42.10.1016/S0924-8579(09)70565-5CrossRefGoogle ScholarPubMed
Parienti, JJ, Thirion, M, Megarbane, B, et al. Femoral vs. jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA. 2008;299(20):24132422.10.1001/jama.299.20.2413CrossRefGoogle ScholarPubMed
Parienti, JJ, Mongardon, N, Megarbane, B, et al. Intravascular complications of central venous catheterization by insertion site. N Engl J Med. 2015;373(13):12201229.CrossRefGoogle ScholarPubMed
Richet, H, Hubert, B, Nitemberg, G, et al. Prospective multicenter study of vascular-catheter-related complications and risk factors for positive central-catheter cultures in intensive care unit patients. J Clin Microbiol. 1990;28(11):25202525.CrossRefGoogle ScholarPubMed
Goetz, AM, Wagener, MM, Miller, JM, Muder, RR. Risk of infection due to central venous catheters: effect of site of placement and catheter type. Infect Control Hosp Epidemiol. 1998;19(11):842845.10.1086/647742CrossRefGoogle ScholarPubMed
Merrer, J, De Jonghe, B, Golliot, F, et al. Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial. JAMA. 2001;286(6):700707.10.1001/jama.286.6.700CrossRefGoogle ScholarPubMed
Cobb, DK, High, KP, Sawyer, RG, et al. A controlled trial of scheduled replacement of central venous and pulmonary-artery catheters. N Engl J Med. 1992;327(15):10621068.10.1056/NEJM199210083271505CrossRefGoogle ScholarPubMed
Cook, D, Randolph, A, Kernerman, P, et al. Central venous catheter replacement strategies: a systematic review of the literature. Crit Care Med. 1997;25(8):14171424.CrossRefGoogle ScholarPubMed
Zurcher, M, Tramer, MR, Walder, B. Colonization and bloodstream infection with single- versus multi-lumen central venous catheters: a quantitative systematic review. Anesth Analg. 2004;99(1):177182.CrossRefGoogle ScholarPubMed
Timsit, JF, Farkas, JC, Boyer, JM, et al. Central vein catheter-related thrombosis in intensive care patients: incidence, risks factors, and relationship with catheter-related sepsis. Chest. 1998;114(1):207213.10.1378/chest.114.1.207CrossRefGoogle ScholarPubMed
Abdelkefi, A, Ben Othman, T, Kammoun, L, et al. Prevention of central venous line-related thrombosis by continuous infusion of low-dose unfractionated heparin, in patients with haemato-oncological disease: a randomized controlled trial. Thromb Haemost. 2004;92(3):654661.Google ScholarPubMed
Abdelkefi, A, Achour, W, Ben Othman, T, et al. Use of heparin-coated central venous lines to prevent catheter-related bloodstream infection. J Support Oncol. 2007;5(6):273278.Google ScholarPubMed
Zingg, W, Posfay-Barbe, KM, Pfister, RE, Touveneau, S, Pittet, D. Individualized catheter surveillance among neonates: a prospective, 8-year, single-center experience. Infect Control Hosp Epidemiol. 2011;32(1):4249.CrossRefGoogle ScholarPubMed
Opilla, MT, Kirby, DF, Edmond, MB. Use of ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients. JPEN J Parenter Enteral Nutr. 2007;31(4):302305.10.1177/0148607107031004302CrossRefGoogle ScholarPubMed
Chen, HS, Wang, FD, Lin, M, Lin, YC, Huang, LJ, Liu, CY. Risk factors for central venous catheter-related infections in general surgery. J Microbiol Immunol Infect = Wei mian yu gan ran za zhi. 2006;39(3):231236.Google ScholarPubMed
Heidegger, CP, Berger, MM, Graf, S, et al. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet. 2013;381(9864):385393.10.1016/S0140-6736(12)61351-8CrossRefGoogle ScholarPubMed
Thibault, R, Makhlouf, AM, Kossovsky, MP, et al. Healthcare-associated infections are associated with insufficient dietary intake: an observational cross-sectional study. PloS one. 2015;10(4):e0123695.10.1371/journal.pone.0123695CrossRefGoogle ScholarPubMed
Zingg, W, Holmes, A, Dettenkofer, M, et al. Hospital organisation, management, and structure for prevention of health-care-associated infection: a systematic review and expert consensus. Lancet Infect Dis. 2015;15(2):212224.10.1016/S1473-3099(14)70854-0CrossRefGoogle ScholarPubMed
Fridkin, SK, Pear, SM, Williamson, TH, Galgiani, JN, Jarvis, WR. The role of understaffing in central venous catheter-associated bloodstream infections. Infect Control Hosp Epidemiol. 1996;17(3):150158.Google ScholarPubMed
Virtanen, M, Kurvinen, T, Terho, K, et al. Work hours, work stress, and collaboration among ward staff in relation to risk of hospital-associated infection among patients. Med Care. 2009;47(3):310318.10.1097/MLR.0b013e3181893c64CrossRefGoogle ScholarPubMed
Pittet, D, Simon, A, Hugonnet, S, Pessoa-Silva, CL, Sauvan, V, Perneger, TV. Hand hygiene among physicians: performance, beliefs, and perceptions. Ann Intern Med. 2004;141(1):18.10.7326/0003-4819-141-1-200407060-00008CrossRefGoogle ScholarPubMed
Cimiotti, JP, Haas, J, Saiman, L, Larson, EL. Impact of staffing on bloodstream infections in the neonatal intensive care unit. Arch Pediatr Adolesc Med. 2006;160(8):832836.10.1001/archpedi.160.8.832CrossRefGoogle ScholarPubMed
Alonso-Echanove, J, Edwards, JR, Richards, MJ, et al. Effect of nurse staffing and antimicrobial-impregnated central venous catheters on the risk for bloodstream infections in intensive care units. Infect Control Hosp Epidemiol. 2003;24(12):916925.10.1086/502160CrossRefGoogle ScholarPubMed
Robert, J, Fridkin, SK, Blumberg, HM, et al. The influence of the composition of the nursing staff on primary bloodstream infection rates in a surgical intensive care unit. Infect Control Hosp Epidemiol. 2000;21(1):1217.10.1086/501690CrossRefGoogle Scholar
Elder, NC, Brungs, SM, Nagy, M, Kudel, I, Render, ML. Intensive care unit nurses’ perceptions of safety after a highly specific safety intervention. Qual Safety Health Care. 17(1):2530. 2008.10.1136/qshc.2006.021949CrossRefGoogle ScholarPubMed
Saint, S, Kowalski, CP, Banaszak-Holl, J, Forman, J, Damschroder, L, Krein, SL. The importance of leadership in preventing healthcare-associated infection: results of a multisite qualitative study. Infect Control Hosp Epidemiol. 2010;31(9):901907.10.1086/655459CrossRefGoogle ScholarPubMed
Sinuff, T, Cook, D, Giacomini, M, Heyland, D, Dodek, P. Facilitating clinician adherence to guidelines in the intensive care unit: a multicenter, qualitative study. Crit Care Med. 2007;35(9):20832089.CrossRefGoogle ScholarPubMed
Snyders, RE, Goris, AJ, Gase, KA, Leone, CL, Doherty, JA, Woeltje, KF. Increasing the reliability of fully automated surveillance for central line-associated bloodstream infections. Infect Control Hosp Epidemiol. 2015;36(12):13961400.CrossRefGoogle ScholarPubMed
Metzger, KE, Rucker, Y, Callaghan, M, et al. The burden of mucosal barrier injury laboratory-confirmed bloodstream infection among hematology, oncology, and stem cell transplant patients. Infect Control Hosp Epidemiol. 2015;36(2):119124.CrossRefGoogle ScholarPubMed
Safdar, N, Fine, JP, Maki, DG. Meta-analysis: methods for diagnosing intravascular device-related bloodstream infection. Ann Intern Med. 2005;142(6):451466.10.7326/0003-4819-142-6-200503150-00011CrossRefGoogle ScholarPubMed
Siegman-Igra, Y, Anglim, AM, Shapiro, DE, Adal, KA, Strain, BA, Farr, BM. Diagnosis of vascular catheter-related bloodstream infection: a meta-analysis. J Clin Microbiol. 1997;35(4):928936.10.1128/jcm.35.4.928-936.1997CrossRefGoogle ScholarPubMed
Blot, F, Nitenberg, G, Chachaty, E, et al. Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures. Lancet. 1999;354(9184):10711077.10.1016/S0140-6736(98)11134-0CrossRefGoogle ScholarPubMed
Woeltje, KF, Butler, AM, Goris, AJ, et al. Automated surveillance for central line-associated bloodstream infection in intensive care units. Infect Control Hosp Epidemiol. 2008;29(9):842846.10.1086/590261CrossRefGoogle ScholarPubMed
Hota, B, Lin, M, Doherty, JA, et al. Formulation of a model for automating infection surveillance: algorithmic detection of central-line associated bloodstream infection. J Am Med Informatics Assoc: JAMIA. 2010;17(1):4248.10.1197/jamia.M3196CrossRefGoogle Scholar
Khouli, H, Jahnes, K, Shapiro, J, et al. Performance of medical residents in sterile techniques during central vein catheterization: randomized trial of efficacy of simulation-based training. Chest. 2011;139(1):8087.10.1378/chest.10-0979CrossRefGoogle ScholarPubMed
Mimoz, O, Lucet, JC, Kerforne, T, et al. Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial. Lancet. 2015;386(10008):20692077.10.1016/S0140-6736(15)00244-5CrossRefGoogle ScholarPubMed
Cartier, V, Haenny, A, Inan, C, Walder, B, Zingg, W. No association between ultrasound-guided insertion of central venous catheters and bloodstream infection: a prospective observational study. J Hosp Infect. 2014;87(2):103108.10.1016/j.jhin.2014.03.009CrossRefGoogle ScholarPubMed
Dumyati, G, Concannon, C, van Wijngaarden, E, et al. Sustained reduction of central line-associated bloodstream infections outside the intensive care unit with a multimodal intervention focusing on central line maintenance. Am J Infect Control. 2014;42(7):723730.CrossRefGoogle ScholarPubMed
Gueri, K, Wagner, J, Rains, K, Bessesen, M. Reduction in central line–associated bloodstream infections by implementation of a postinsertion care bundle. Am J Infect Control. 2010;38(6):430433.CrossRefGoogle Scholar
Blot, K, Bergs, J, Vogelaers, D, Blot, S, Vandijck, D. Prevention of central line–associated bloodstream infections through quality improvement interventions: a systematic review and meta-analysis. Clin Infect Dis. 2014;59(1):96105.10.1093/cid/ciu239CrossRefGoogle Scholar
Apisarnthanarak, A, Thongphubeth, K, Yuekyen, C, Warren, DK, Fraser, VJ. Effectiveness of a catheter-associated bloodstream infection bundle in a Thai tertiary care center: a 3-year study. Am J Infect Control. 2010;38(6):449455.CrossRefGoogle Scholar
Bion, J, Richardson, A, Hibbert, P, et al. “Matching Michigan”: a 2-year stepped interventional programme to minimise central venous catheter-blood stream infections in intensive care units in England. BMJ Qual Safety. 2013;22(2):110123.10.1136/bmjqs-2012-001325CrossRefGoogle ScholarPubMed
DePalo, VA, McNicoll, L, Cornell, M, Rocha, JM, Adams, L, Pronovost, PJ. The Rhode Island ICU collaborative: a model for reducing central line-associated bloodstream infection and ventilator-associated pneumonia statewide. Qual Saf Health Care. 2010;19(6):555561.Google Scholar
Eggimann, P, Harbarth, S, Constantin, MN, Touveneau, S, Chevrolet, JC, Pittet, D. Impact of a prevention strategy targeted at vascular-access care on incidence of infections acquired in intensive care. Lancet. 2000;355(9218):1864–8.10.1016/S0140-6736(00)02291-1CrossRefGoogle ScholarPubMed
Guerin, K, Wagner, J, Rains, K, Bessesen, M. Reduction in central line–associated bloodstream infections by implementation of a postinsertion care bundle. Am J Infect Control. 38(6):430–3. 2010.CrossRefGoogle ScholarPubMed
Marra, AR, Cal, RG, Durao, MS, Correa, L, Guastelli, LR, Moura, DF Jr., et al. Impact of a program to prevent central line-associated bloodstream infection in the zero tolerance era. Am J Infect Control. 2010.CrossRefGoogle ScholarPubMed
Miller, MR, Griswold, M, Harris, JM, et al. Decreasing PICU catheter-associated bloodstream infections: NACHRI’s quality transformation efforts. Pediatrics. 125(2):206213. 2010.10.1542/peds.2009-1382CrossRefGoogle ScholarPubMed
Palomar, M, Alvarez-Lerma, F, Riera, A, et al. Impact of a national multimodal intervention to prevent catheter-related bloodstream infection in the ICU: the Spanish experience. Crit Care Med. 2013;41(10):23642372.10.1097/CCM.0b013e3182923622CrossRefGoogle ScholarPubMed
Peredo, R, Sabatier, C, Villagra, A, et al. Reduction in catheter-related bloodstream infections in critically ill patients through a multiple system intervention. Eur J Clin Microbiol Infect Dis. 2010;29(9):11731177.10.1007/s10096-010-0971-6CrossRefGoogle ScholarPubMed
Perez Parra, A, Cruz Menarguez, M, Perez Granda, MJ, Tomey, MJ, Padilla, B, Bouza, E. A simple educational intervention to decrease incidence of central line-associated bloodstream infection (CLABSI) in intensive care units with low baseline incidence of CLABSI. Infect Control Hosp Epidemiol. 2010;31(9):964967.10.1086/655841CrossRefGoogle ScholarPubMed
Schulman, J, Stricof, R, Stevens, TP, et al. Statewide NICU central-line-associated bloodstream infection rates decline after bundles and checklists. Pediatrics. 2011;127(3):436444.CrossRefGoogle ScholarPubMed
Venkatram, S, Rachmale, S, Kanna, B. Study of device use adjusted rates in health care–associated infections after implementation of “bundles” in a closed-model medical intensive care unit. J Crit Care. 2010;25(1):174 e11e18.CrossRefGoogle Scholar
Weber, DJ, Brown, VM, Sickbert-Bennett, EE, Rutala, WA. Sustained and prolonged reduction in central line-associated bloodstream infections as a result of multiple interventions. Infect Control Hosp Epidemiol. 2010;31(8):875877.CrossRefGoogle ScholarPubMed
Zingg, W, Imhof, A, Maggiorini, M, Stocker, R, Keller, E, Ruef, C. Impact of a prevention strategy targeting hand hygiene and catheter care on the incidence of catheter-related bloodstream infections. Crit Care Med. 2009;37(7):21672173; quiz 80.CrossRefGoogle ScholarPubMed
Zingg, W, Cartier, V, Inan, C, et al. Hospital-wide multidisciplinary, multimodal intervention programme to reduce central venous catheter–associated bloodstream infection. PLoS One. 2014;9(4):e93898.CrossRefGoogle ScholarPubMed
Sherertz, RJ, Ely, EW, Westbrook, DM, et al. Education of physicians-in-training can decrease the risk for vascular catheter infection. Ann Intern Med. 2000;132(8):641648.CrossRefGoogle ScholarPubMed
Barsuk, JH, Cohen, ER, Feinglass, J, McGaghie, WC, Wayne, DB. Use of simulation-based education to reduce catheter-related bloodstream infections. Arch Intern Med. 2009;169(15):14201423.10.1001/archinternmed.2009.215CrossRefGoogle ScholarPubMed
Evans, LV, Dodge, KL, Shah, TD, et al. Simulation training in central venous catheter insertion: improved performance in clinical practice. Acad Med. 2010;85(9):14621469.10.1097/ACM.0b013e3181eac9a3CrossRefGoogle ScholarPubMed
Marra, AR, Guastelli, LR, de Araujo, CM, et al. Positive deviance: a new strategy for improving hand hygiene compliance. Infect Control Hosp Epidemiol. 2010;31(1):1220.10.1086/649224CrossRefGoogle ScholarPubMed
Joshi, SC, Diwan, V, Tamhankar, AJ, et al. Qualitative study on perceptions of hand hygiene among hospital staff in a rural teaching hospital in India. J Hosp Infect. 2012;80(4):340344.10.1016/j.jhin.2011.12.017CrossRefGoogle Scholar
Turnberg, W, Daniell, W, Simpson, T, et al. Personal healthcare worker (HCW) and work-site characteristics that affect HCWs’ use of respiratory-infection control measures in ambulatory healthcare settings. Infect Control Hosp Epidemiol. 2009;30(1):4752.10.1086/592707CrossRefGoogle ScholarPubMed
Nicol, PW, Watkins, RE, Donovan, RJ, Wynaden, D, Cadwallader, H. The power of vivid experience in hand hygiene compliance. J Hosp Infect 72(1):3642. 2009.CrossRefGoogle ScholarPubMed
Larson, EL, Quiros, D, Lin, SX. Dissemination of the CDC’s Hand Hygiene Guideline and impact on infection rates. Am J Infect Control. 2007;35(10):666675.CrossRefGoogle ScholarPubMed
Raad, II, Hohn, DC, Gilbreath, BJ, et al. Prevention of central venous catheter–related infections by using maximal sterile barrier precautions during insertion. Infect Control Hosp Epidemiol. 1994;15(4 Pt 1):231238.CrossRefGoogle ScholarPubMed
Quiros, D, Lin, S, Larson, EL. Attitudes toward practice guidelines among intensive care unit personnel: a cross-sectional anonymous survey. Heart Lung. 36(4):287297. 2007:Aug.CrossRefGoogle ScholarPubMed
Haustein, T, Gastmeier, P, Holmes, A, et al. Use of benchmarking and public reporting for infection control in four high-income countries. Lancet Infect Dis. 2011;11(6):471481.10.1016/S1473-3099(10)70315-7CrossRefGoogle ScholarPubMed
Damschroder, LJ, Aron, DC, Keith, RE, Kirsh, SR, Alexander, JA, Lowery, JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009;4:50.CrossRefGoogle Scholar
Gurses, AP, Murphy, DJ, Martinez, EA, Berenholtz, SM, Pronovost, PJ. A practical tool to identify and eliminate barriers to compliance with evidence-based guidelines. Jt Comm J Qual Patient Saf. 2009;35(10):526532, 485.Google ScholarPubMed
Hansen, S, Schwab, F, Behnke, M, et al. National influences on catheter-associated bloodstream infection rates: practices among national surveillance networks participating in the European HELICS project. J Hosp Infect. 2009;71(1):6673.CrossRefGoogle ScholarPubMed
Hockenhull, JC, Dwan, KM, Smith, GW, et al. The clinical effectiveness of central venous catheters treated with anti-infective agents in preventing catheter-related bloodstream infections: a systematic review. Crit Care Med. 2009;37(2):702–12.CrossRefGoogle ScholarPubMed
Walder, B, Pittet, D, Tramer, MR. Prevention of bloodstream infections with central venous catheters treated with anti-infective agents depends on catheter type and insertion time: evidence from a meta-analysis. Infect Control Hosp Epidemiol. 2002;23(12):748756.10.1086/502005CrossRefGoogle ScholarPubMed
Falagas, ME, Fragoulis, K, Bliziotis, IA, Chatzinikolaou, I. Rifampicin-impregnated central venous catheters: a meta-analysis of randomized controlled trials. J Antimicrob Chemother. 2007;59(3):359369.CrossRefGoogle ScholarPubMed
Cherry-Bukowiec, JR, Denchev, K, Dickinson, S, et al. Prevention of catheter-related blood stream infection: back to basics? Surg Infect (Larchmt). 2011;12(1):2732.CrossRefGoogle ScholarPubMed
Marschall, J, Mermel, LA, Classen, D, et al. Strategies to prevent central line–associated bloodstream infections in acute care hospitals. Infect Control Hosp Epidemiol. 2008;29 Suppl 1:S2230.10.1086/591059CrossRefGoogle ScholarPubMed
O’Grady, NP, Alexander, M, Burns, LA, et al. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control. 2011;39(4 Suppl 1):S1S34.CrossRefGoogle ScholarPubMed
Timsit, JF, Schwebel, C, Bouadma, L, et al. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. JAMA. 2009;301(12):12311241.CrossRefGoogle ScholarPubMed
Timsit, JF, Mimoz, O, Mourvillier, B, et al. Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults. Am J Respir Crit Care Med. 2012;186(12):12721278.10.1164/rccm.201206-1038OCCrossRefGoogle ScholarPubMed
Ruschulte, H, Franke, M, Gastmeier, P, et al. Prevention of central venous catheter related infections with chlorhexidine gluconate impregnated wound dressings: a randomized controlled trial. Ann Hematol. 2009;88(3):267272.10.1007/s00277-008-0568-7CrossRefGoogle ScholarPubMed
Mermel, LA, Allon, M, Bouza, E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter–related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2009;49(1):145.CrossRefGoogle ScholarPubMed
Sherertz, RJ, Boger, MS, Collins, CA, Mason, L, Raad, II. Comparative in vitro efficacies of various catheter lock solutions. Antimicrob Agents Chemother. 2006;50(5):1865868.10.1128/AAC.50.5.1865-1868.2006CrossRefGoogle ScholarPubMed
Takla, TA, Zelenitsky, SA, Vercaigne, LM. Effectiveness of a 30% ethanol/4% trisodium citrate locking solution in preventing biofilm formation by organisms causing haemodialysis catheter-related infections. J Antimicrob Chemother. 2008;62(5):10241026.CrossRefGoogle ScholarPubMed
Cober, MP, Kovacevich, DS, Teitelbaum, DH. Ethanol-lock therapy for the prevention of central venous access device infections in pediatric patients with intestinal failure. JPEN J Parenter Enteral Nutr. 2010;35(1):6773.CrossRefGoogle ScholarPubMed
Jones, BA, Hull, MA, Richardson, DS, et al. Efficacy of ethanol locks in reducing central venous catheter infections in pediatric patients with intestinal failure. J Pediatr Surg. 2010;45(6):12871293.CrossRefGoogle ScholarPubMed
Mermel, LA, Alang, N. Adverse effects associated with ethanol catheter lock solutions: a systematic review. J Antimicrob Chemother. 2014;69(10):26112619.CrossRefGoogle ScholarPubMed
Dillon, PW, Jones, GR, Bagnall-Reeb, HA, Buckley, JD, Wiener, ES, Haase, GM. Prophylactic urokinase in the management of long-term venous access devices in children: a Children’s Oncology Group study. J Clin Oncol. 2004;22(13):27182723.10.1200/JCO.2004.07.019CrossRefGoogle ScholarPubMed
Kalmanti, M, Germanakis, J, Stiakaki, E, et al. Prophylaxis with urokinase in pediatric oncology patients with central venous catheters. Pediatr Hematol Oncol. 2002;19(3):173179.CrossRefGoogle ScholarPubMed
van Rooden, CJ, Schippers, EF, Guiot, HF, et al. Prevention of coagulase-negative staphylococcal central venous catheter–related infection using urokinase rinses: a randomized double-blind controlled trial in patients with hematologic malignancies. J Clin Oncol. 2008;26(3):428433.CrossRefGoogle ScholarPubMed
Maki, DG, Ash, SR, Winger, RK, Lavin, P. A novel antimicrobial and antithrombotic lock solution for hemodialysis catheters: a multi-center, controlled, randomized trial. Crit Care Med. 2011;39(4):613620.CrossRefGoogle ScholarPubMed
Climo, MW, Sepkowitz, KA, Zuccotti, G, et al. The effect of daily bathing with chlorhexidine on the acquisition of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial. Crit Care Med. 2009;37(6):185818565.CrossRefGoogle ScholarPubMed
Munoz-Price, LS, Hota, B, Stemer, A, Weinstein, RA. Prevention of bloodstream infections by use of daily chlorhexidine baths for patients at a long-term acute care hospital. Infect Control Hosp Epidemiol. 2009;30(11):10311035.10.1086/644751CrossRefGoogle Scholar
Climo, MW, Yokoe, DS, Warren, DK, et al. Effect of daily chlorhexidine bathing on hospital-acquired infection. N Engl J Med. 2013;368(6):533–42.10.1056/NEJMoa1113849CrossRefGoogle ScholarPubMed
Huang, SS, Septimus, E, Kleinman, K, et al. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med. 2013;368(24):2255–65.CrossRefGoogle ScholarPubMed
Quach, C, Milstone, AM, Perpete, C, Bonenfant, M, Moore, DL, Perreault, T. Chlorhexidine bathing in a tertiary care neonatal intensive care unit: impact on central line–associated bloodstream infections. Infect Control Hosp Epidemiol. 2014;35(2):158163.CrossRefGoogle Scholar
Pittet, D, Hugonnet, S, Harbarth, S, et al. Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Infection Control Programme.[Erratum appears in Lancet 2000 Dec 23–30;356(9248):2196]. Lancet. 2000;356(9238):1307–1312.Google ScholarPubMed
Darouiche, RO, Wall, MJ Jr., Itani, KM, et al. Chlorhexidine-alcohol versus povidone-iodine for surgical-site antisepsis. N Engl J Med. 2010;362(1):1826.10.1056/NEJMoa0810988CrossRefGoogle ScholarPubMed
Batra, R, Cooper, BS, Whiteley, C, Patel, AK, Wyncoll, D, Edgeworth, JD. Efficacy and limitation of a chlorhexidine-based decolonization strategy in preventing transmission of methicillin-resistant Staphylococcus aureus in an intensive care unit. Clin Infect Dis. 2010;50(2):210217.10.1086/648717CrossRefGoogle Scholar
Karakitsos, D, Labropoulos, N, De Groot, E, et al. Real-time ultrasound-guided catheterisation of the internal jugular vein: a prospective comparison with the landmark technique in critical care patients. Crit Care. 2006;10(6):R162.10.1186/cc5101CrossRefGoogle ScholarPubMed
Zingg, W, Cartier, V, Walder, B. No association between ultrasound-guided insertion of central venous catheters and bloodstream infection: a prospective observational study. J Hosp Infect. 2015.10.1016/j.jhin.2015.01.007CrossRefGoogle ScholarPubMed

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