Nezhat's Textbook of Minimally Invasive Surgery Published online by Cambridge University Press: 06 November 2025
The majority of surgical and medical conditions diagnosed in utero are best managed after delivery. There is a finite list of conditions that when diagnosed antenatally result in death or long-standing morbidity. This raises the possibility that treatment may be best approached prenatally. Almost 30 years ago, the International Fetal Medicine & Surgery Society (IFMSS) developed the criteria for fetal surgery. The criteria as written at that time included an accurate diagnosis, a known natural history of the disease, no available effective postnatal therapy, proven efficacy of a prenatal intervention, and the requirement that interventions for the fetus would be performed in a specialized multidisciplinary center.[1] Fetal therapy has expanded since then to treat nonlethal conditions so as to reduce long-term morbidity.
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