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Chapter 11 - Endometriosis

Published online by Cambridge University Press:  06 November 2025

Camran R. Nezhat
Affiliation:
Stanford University School of Medicine, California
Farr R. Nezhat
Affiliation:
Nezhat Surgery for Gynecology/Oncology, New York
Ceana Nezhat
Affiliation:
Nezhat Medical Center, Atlanta
Nisha Lakhi
Affiliation:
Richmond University Medical Center, New York
Azadeh Nezhat
Affiliation:
Nezhat Institute and Center for Special Minimally Invasive and Robotic Surgery, California
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Summary

Endometriosis is classically defined as the presence of endometrial glands and stroma in ectopic locations. Affecting 6–10% of reproductive-aged women, endometriosis can result in dysmenorrhea, dyspareunia, chronic pelvic pain, and/or subfertility.[1,2] The prevalence of this condition in women experiencing pain, infertility, or both is as high as 50%. Endometriosis is a debilitating condition, posing quality-of-life (QOL) issues for the individual patient.[3] The disorder represents a major cause of gynecologic hospitalization in the US, estimated to have exceeded $69 billion in healthcare costs for diagnosis and treatment and improving QOL in 2009.[4] The significant individual and public health concerns associated with endometriosis underscore the importance of understanding its pathogenesis. The first recorded description of pathology consistent with endometriosis was provided by Shroen in 1690.[5] Despite the passage of time and extensive investigation, the exact pathogenesis of this enigmatic disorder remains unknown, although about 50% of risk of developing endometriosis is due to genetic factors and 50% to environmental factors.

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Nezhat's Textbook of Minimally Invasive Surgery
Including Hysteroscopy, Vaginoscopy and Robotic-Assisted Procedures
, pp. 284 - 357
Publisher: Cambridge University Press
Print publication year: 2025

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References

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  • Endometriosis
  • Edited by Camran R. Nezhat, Stanford University School of Medicine, California, Farr R. Nezhat, Nezhat Surgery for Gynecology/Oncology, New York, Ceana Nezhat, Nezhat Medical Center, Atlanta, Nisha Lakhi, Richmond University Medical Center, New York, Azadeh Nezhat, Nezhat Institute and Center for Special Minimally Invasive and Robotic Surgery, California
  • Book: Nezhat's Textbook of Minimally Invasive Surgery
  • Online publication: 06 November 2025
  • Chapter DOI: https://doi.org/10.1017/9781108561440.013
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  • Endometriosis
  • Edited by Camran R. Nezhat, Stanford University School of Medicine, California, Farr R. Nezhat, Nezhat Surgery for Gynecology/Oncology, New York, Ceana Nezhat, Nezhat Medical Center, Atlanta, Nisha Lakhi, Richmond University Medical Center, New York, Azadeh Nezhat, Nezhat Institute and Center for Special Minimally Invasive and Robotic Surgery, California
  • Book: Nezhat's Textbook of Minimally Invasive Surgery
  • Online publication: 06 November 2025
  • Chapter DOI: https://doi.org/10.1017/9781108561440.013
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  • Endometriosis
  • Edited by Camran R. Nezhat, Stanford University School of Medicine, California, Farr R. Nezhat, Nezhat Surgery for Gynecology/Oncology, New York, Ceana Nezhat, Nezhat Medical Center, Atlanta, Nisha Lakhi, Richmond University Medical Center, New York, Azadeh Nezhat, Nezhat Institute and Center for Special Minimally Invasive and Robotic Surgery, California
  • Book: Nezhat's Textbook of Minimally Invasive Surgery
  • Online publication: 06 November 2025
  • Chapter DOI: https://doi.org/10.1017/9781108561440.013
Available formats
×