Leadership at all levels is pivotal as school–university partnerships (SUPs) seek to cultivate a culture of collaboration. Leaders across roles – be they school principals, university faculty and administrators, or teacher leaders – act as linchpins who not only facilitate the flow of knowledge and resources between institutions, but also engender a sense of shared vision and purpose. Leadership requires navigating the complexities of differing institutional norms, aligning diverse stakeholder interests, and fostering an environment conducive to collaborative innovation. The complex endeavor of developing dynamic leadership and robust partnerships between schools and universities underscores the pivotal work of partnerships seeking simultaneous renewal. This part of the handbook includes four compelling chapters that delineate both conceptual understanding of the work of leaders as well as the practical ramifications of leadership within SUPs.