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1 results

  • 14a - Photons and Particles

  • from Chapter 14 - High Energy Forms: Employing the Spectrum of Energy as Surgical Adjuvants
  • Edited by Benjamin Hartley, Weill Cornell Medical Center, Philip E. Stieg, Weill Cornell Medical College, Rohan Ramakrishna, Weill Cornell Medical College, Michael L. J. Apuzzo, Adjunct of Yale Medical School and Weill Cornell Medical College
  • Book:
    Neurosurgery
    Published online:
    29 November 2025
    Print publication:
    18 September 2025, pp 269-283

  • Summary

    The concept of radiosurgery was first introduced by Lars Leksell in 1951. Throughout the decades, the indications for stereotactic radiosurgery (SRS) and available SRS technology have expanded. Currently, SRS is indicated for selected patients with malignant and benign brain tumors such as metastases, recurrent glioblastoma and WHO Grade II meningioma, vestibular schwannoma, WHO Grade I meningioma, recurrent non-functioning and functioning pituitary adenoma. SRS is also indicated for patients with cerebral vascular malformations, cranial nerve neuralgias, and for patients suffering from obsessive compulsive disorder refractory to medications. Though the indications of SRS and the number of SRS procedures performed annually increase, SRS literature is limited mainly to retrospective studies providing low Level of evidence. Moreover, exposure to SRS procedures during neurosurgical training seems inadequate. Therefore, development of randomized studies and national or international SRS registries, and adequate training of neurosurgical residents to improve patient care is necessary.