Identifying the populations and regions most vulnerable to climate change, this chapter features voices including Nakeeyat Dramani Sam from Ghana, highlighting the disproportionate impacts on young people and marginalised groups. Understanding ‘vulnerability’ is the key to addressing climate change. Jevanic Henry from Saint Lucia discusses rising sea levels and frequent hurricanes threatening coastal communities. The chapter emphasises the need for targeted adaptation strategies and global support to build resilience among low-income countries, small island developing states (SIDS), and Indigenous Peoples, and local communities (IPLCs). Isaac Nemuta, a Maasai pastoralist from Kenya, shares how prolonged droughts are decimating livestock. The chapter discusses the unique challenges faced by vulnerable groups, including limited resources, inadequate infrastructure, and political marginalisation. Calls for increased international aid, robust policy measures, and tailored climate resilience plans are emphasised, with examples like the Climate Prosperity Plans from Bangladesh and the Philippines. Empowering local communities through education, sustainable practices, and inclusive governance is crucial.